Patents by Inventor John Tobin
John Tobin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220226454Abstract: Vaccines for Porphyromonas gingivalis are described. Also provided are methods of treating or preventing a disorder or disease by administering the vaccine.Type: ApplicationFiled: January 10, 2022Publication date: July 21, 2022Inventors: Peter L. Nara, Jan Stanislaw Potempa, John Knox Tobin, Gregory John Tobin
-
Patent number: 11116233Abstract: The invention pertains to a process for simultaneous producing an infant formula product and an acidic dairy product from defatted animal milk, comprising (a) processing the milk into a casein stream, a whey protein stream and a lactose stream, by: (i) subjecting the defatted animal milk to a filtration step over a microfiltration membrane capable of retaining bacteria and permeating milk proteins, to provide a debacterialized milk as permeate; (ii) subjecting the permeate originating from step (i) to a filtration step over a microfiltration membrane capable of retaining casein and permeating whey proteins, to provide a casein stream as retentate and a permeate comprising whey protein; (iii) fractionating the permeate originating from step (ii) into a whey protein stream and a lactose stream; (b) combining part of the casein stream, at least part of the whey protein stream originating from step (a) and a lactose source to obtain a recombined stream, wherein the lactose source comprises acid whey; (c) using thType: GrantFiled: August 8, 2017Date of Patent: September 14, 2021Assignees: Compagnie Gervais Danone, N.V. NutriciaInventors: Franck David, Claire Queguiner, Laurent Schmitt, Gerrit Hols, John Tobin, Raoul Charles Johan Moonen, Evelien Louise Van Eijk-Van Boxtel, Evan Abrahamse
-
Patent number: 11109605Abstract: The invention pertains to a process for simultaneous producing an infant formula product and a dairy product from defatted animal milk, comprising (a) processing the milk into a casein stream, a whey protein stream and a lactose stream by a combination of microfiltration and ultrafiltration, wherein the casein stream originates from the microfiltration as retentate, the whey protein stream originates from the ultrafiltration as retentate and the lactose stream originates from the ultrafiltration as permeate; (b) combining at least part of the whey protein stream originating from step (a) and a lactose source to obtain are combined stream; (c) using the recombined stream originating from step (b) in the manufacture of the infant formula product; and (d) using at least part of the casein stream originating from step (a) and defatted animal milk in the manufacture of the dairy product.Type: GrantFiled: August 8, 2017Date of Patent: September 7, 2021Assignees: Compagnie Gervals Danone, N.V. NutriciaInventors: Franck David, Claire Queguiner, Laurent Schmitt, Gerrit Hols, John Tobin, Raoul Charles Johan Moonen
-
Patent number: 10772339Abstract: The invention relates to a process for the treatment of animal skim milk and for the production of an infant formula base product from animal skim milk, which process is highly efficient and cost effective, as only membrane filtration techniques, such as microfiltration and ultrafiltration, are required. By carefully controlling the process parameters, a product is obtained in which most of the major components are within the desired range for an infant formula base product. The invention also relates to products obtainable by the process according to the invention.Type: GrantFiled: March 12, 2012Date of Patent: September 15, 2020Assignee: N.V. NUTRICIAInventors: John Tobin, Philip Kelly, Rudolph Eduardus Maria Verdurmen, Antonie Van Baalen, Roeland Van Eerten
-
Patent number: 10674739Abstract: Claimed is the preparation of an infant formula base product, comprising: (a) microfiltration (ME) of animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer and operating with a volume concentration factor of 1.5-8, resulting in a retentate (MFR) and a permeate (MFP); (b) ultrafiltration (UF) of the MEP originating from step (a) over a membrane having a molecular weight cut-off of at most 25 kDa and operating with a volume concentration factor of 1.5-8, resulting in a retentate (UFR) and a permeate fUEP); (c) combining the MFR from step (a) and the UFR from step (b), to obtain a defined casein/whey ratio. Alternatively, the product of step (a) is used as a protein source. Claimed is also a composition comprising 40-50 g casein, 30-40 g lactose and 5-16 g ash per 100 g dry weight.Type: GrantFiled: September 19, 2014Date of Patent: June 9, 2020Assignee: N.V. NUTRICIAInventors: John Tobin, Rudolph Eduardus Maria Verdurmen
-
Publication number: 20190166864Abstract: The invention pertains to a process for simultaneous producing an infant formula product and a dairy product from defatted animal milk, comprising (a) processing the milk into a casein stream, a whey protein stream and a lactose stream by a combination of microfiltration and ultrafiltration, wherein the casein stream originates from the microfiltration as retentate, the whey protein stream originates from the ultrafiltration as retentate and the lactose stream originates from the ultrafiltration as permeate; (b) combining at least part of the whey protein stream originating from step (a) and a lactose source to obtain are combined stream; (c) using the recombined stream originating from step (b) in the manufacture of the infant formula product; and (d) using at least part of the casein stream originating from step (a) and defatted animal milk in the manufacture of the dairy product.Type: ApplicationFiled: August 8, 2017Publication date: June 6, 2019Applicants: COMPAGNIE GERVAIS DANONE, N.V. NUTRICIAInventors: Franck DAVID, Claire QUEGUINER, Laurent SCHMITT, Gerrit HOLS, John TOBIN, Raoul Charles Johan MOONEN
-
Publication number: 20190159472Abstract: The invention pertains to a process for simultaneous producing an infant formula product and an acidic dairy product from defatted animal milk, comprising (a) processing the milk into a casein stream, a whey protein stream and a lactose stream, by: (i) subjecting the defatted animal milk to a filtration step over a microfiltration membrane capable of retaining bacteria and permeating milk proteins, to provide a debacterialized milk as permeate; (ii) subjecting the permeate originating from step (i) to a filtration step over a microfiltration membrane capable of retaining casein and permeating whey proteins, to provide a casein stream as retentate and a permeate comprising whey protein; (iii) fractionating the permeate originating from step (ii) into a whey protein stream and a lactose stream; (b) combining part of the casein stream, at least part of the whey protein stream originating from step (a) and a lactose source to obtain a recombined stream, wherein the lactose source comprises acid whey; (c) using thType: ApplicationFiled: August 8, 2017Publication date: May 30, 2019Applicants: COMPAGNIE GERVAIS DANONE, N.V. NUTRICIAInventors: Franck DAVID, Claire QUEGUINER, Laurent SCHMITT, Gerrit HOLS, John TOBIN, Raoul Charles Johan MOONEN, Evelien Louise VAN EIJK-VAN BOXTEL, Evan ABRAHAMSE
-
Patent number: 10021890Abstract: The invention relates to a process for treating animal skim milk and sweet whey and/or acid whey, having: (a) ultrafiltration (UF1) of a first liquid composition including animal skim milk with 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, over a first ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kDa using a volume concentration factor of 1.5-6 to obtain a retentate (UFR1) and a permeate (UFP1); (b) ultrafiltration (UF2) of a second liquid composition including sweet whey and/or acid whey over a second ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kDa using a volume concentration factor of 2-15 to obtain a retentate (UFR2) and a permeate (UFP2); and (c) mixing the UF retentate originating from step (a) with the UF retentate originating from step (b) to obtain a mixture of UF retentates.Type: GrantFiled: April 3, 2014Date of Patent: July 17, 2018Assignee: N.V. NutriciaInventors: John Tobin, Jitti Chiaranaipanich, Rudolph Eduardus Maria Verdurmen, Antonius Hendricus Janssen, Olivier Bertrand Rabartin, Raoul Charles Johan Moonen, Martijn Johannes Van Der Hoeven
-
Patent number: 9993009Abstract: A process and system is shown for obtaining a dry milk formula, having (a-i) ultrafiltration of an animal skim milk composition having 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, and (a-ii) ultrafiltration of an animal whey composition having 0-25 wt % casein and 75-100 wt % whey proteins, based on total protein; or (a-iii) ultrafiltration of a mixture of the compositions of (a-i) and (a-ii), (b) removing polyvalent ions from the UF permeate originating from step (a-i) and/or (a-ii) or (a-iii) to obtain at least one softened UF permeate; (c) combining the at least one softened UF permeate with a UF retentate to obtain a combined product; and (d) drying the combined product to obtain a dry milk formula.Type: GrantFiled: April 3, 2014Date of Patent: June 12, 2018Assignee: N.V. NutriciaInventors: John Tobin, Jitti Chiaranaipanich, Rudolph Eduardus Maria Verdurmen, Antonius Hendricus Janssen, Olivier Bertrand Rabartin, Raoul Charles Johan Moonen, Martijn Johannes Van Der Hoeven
-
Publication number: 20160205960Abstract: Claimed is the preparation of an infant formula base product, comprising: (a) microfiltration (ME) of animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer and operating with a volume concentration factor of 1.5-8, resulting in a retentate (MFR) and a permeate (MFP); (b) ultrafiltration (UF) of the MEP originating from step (a) over a membrane having a molecular weight cut-off of at most 25 kDa and operating with a volume concentration factor of 1.5-8, resulting in a retentate (UFR) and a permeate fUEP); (c) combining the MFR from step (a) and the UFR from step (b), to obtain a defined casein/whey ratio. Alternatively, the product of step (a) is used as a protein source. Claimed is also a composition comprising 40-50 g casein, 30-40 g lactose and 5-16 g ash per 100 g dry weight.Type: ApplicationFiled: September 19, 2014Publication date: July 21, 2016Applicant: N.V. NutriciaInventors: John TOBIN, Rudolph Eduardus Maria VERDURMEN
-
Publication number: 20160044932Abstract: A process and system is disclosed for obtaining a dry milk formula, comprising (a-i) ultrafiltration of an animal skim milk composition comprising 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, and (a-ii) ultrafiltration of an animal whey composition comprising 0-25 wt % casein and 75-100 wt % whey proteins, based on total protein; or (a-iii) ultrafiltration of a mixture of the compositions of (a-i) and (a-ii), (b) removing polyvalent ions from the UF permeate originating from step (a-i) and/or (a-ii) or (a-iii) to obtain at least one softened UF permeate; (c) combining the at least one softened UF permeate with a UF retentate to obtain a combined product; and (d) drying the combined product to obtain a dry milk formula.Type: ApplicationFiled: April 3, 2014Publication date: February 18, 2016Applicant: N.V. NutriciaInventors: John TOBIN, Jitti CHIARANAIPANICH, Rudolph Eduardus Maria VERDURMEN, Antonius Hendricus JANSSEN, Olivier Bertrand RABARTIN, Raoul Charles Johan MOONEN, Martijn Johannes VAN DER HOEVEN
-
Publication number: 20160044933Abstract: The invention relates to a process for treating animal skim milk and sweet whey and/or acid whey, comprising: (a) ultrafiltration (UF1) of a first liquid composition comprising animal skim milk with 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, over a first ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kDa using a volume concentration factor of 1.5-6 to obtain a retentate (UFR1) and a permeate (UFP1); (b) ultrafiltration (UF2) of a second liquid composition comprising sweet whey and/or acid whey over a second ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kDa using a volume concentration factor of 2-15 to obtain a retentate (UFR2) and a permeate (UFP2); and (c) mixing the UF retentate originating from step (a) with the UF retentate originating from step (b) to obtain a mixture of UF retentates.Type: ApplicationFiled: April 3, 2014Publication date: February 18, 2016Applicant: N.V. NutriciaInventors: John TOBIN, Jitti CHIARANAIPANICH, Rudolph Eduardus Maria VERDURMEN, Antonius Hendricus JANSSEN, Olivier Bertrand RABARTIN, Raoul Charles Johan MOONEN, Martijn Johannes VAN DER HOEVEN
-
Publication number: 20150093490Abstract: The invention relates to a process for the treatment of animal skim milk and for the production of an infant formula base product from animal skim milk, which process is highly efficient and cost effective, as only membrane filtration techniques, such as microfiltration and ultrafiltration, are required. By carefully controlling the process parameters, a product is obtained in which most of the major components are within the desired range for an infant formula base product. The invention also relates to products obtainable by the process according to the invention.Type: ApplicationFiled: March 12, 2012Publication date: April 2, 2015Inventors: John Tobin, Philip Kelly, Rudolph Eduardus Maria Verdurmen, Antonie Van Baalen, Roeland Van Eerten
-
Patent number: 8883725Abstract: The present invention relates to compositions and methods useful in studying or modulating melanin pigmentation in the skin. Particularly, the invention relates to compositions comprising a substance capable of modulating the activity or expression of ALK6 (SEQ ID 2) or Cdc42 which in turn are capable of modulation of the transfer of melanin from melanocytes to keratinocytes and potentially from keratinocytes to keratinocytes. The invention also relates to assays for identifying such compositions, and methods of modulating skin pigmentation.Type: GrantFiled: September 8, 2009Date of Patent: November 11, 2014Assignee: University of BradfordInventors: Suman Kumar Singh, Desmond John Tobin
-
Publication number: 20110240703Abstract: The present teachings provide hydration systems. Generally, the hydration systems include a storage area, a handle connected to the storage area, and a hydration apparatus contained in a region of the storage area. The hydration apparatus includes a hydration reservoir, a lid having at least one drink opening and a closure for the hydration reservoir, and a tube extending from the lid through the handle and towards the mouth of the user. The hydration system provides enhanced benefits of hydration in a discreet manner without requiring that the user sacrifice freedom or mobility.Type: ApplicationFiled: December 14, 2009Publication date: October 6, 2011Inventors: Marilene Hickmann Tobin, Russell John Tobin
-
Publication number: 20110206625Abstract: The present invention relates to compositions and methods useful in studying or modulating melanin pigmentation in the skin. Particularly, the invention relates to compositions comprising a substance capable of modulating the activity or expression of ALK6 (SEQ ID 2) or Cdc42 which in turn are capable of modulation of the transfer of melanin from melanocytes to keratinocytes and potentially from keratinocytes to keratinocytes. The invention also relates to assays for identifying such compositions, and methods of modulating skin pigmentation.Type: ApplicationFiled: September 8, 2009Publication date: August 25, 2011Inventors: Suman Kumar Singh, Desmond John Tobin
-
Publication number: 20100071503Abstract: The present invention is directed toward a cam assembly comprising a cam, a drive shaft and an adjustable screw. The cam includes a first side, a second side opposite the first side, an outer perimeter and a thickness between the first and second sides. The cam further has a first elongated bore through the first and second sides and the thickness of the cam, wherein the first elongated bore has a length radially oriented in the cam and a first end and a second end. The cam further has an elongated threaded hole extending from the outer perimeter to and being in communication with the first elongated bore. The drive shaft extends through the first elongated bore. The adjustment screw is within the elongated threaded hole and is engaged with the drive shaft, wherein the cam assembly is constructed and arranged such the drive shaft can be adjustably positioned and fixedly secured relative to the cam at a plurality of positions along the length of the first elongated bore.Type: ApplicationFiled: September 23, 2008Publication date: March 25, 2010Applicant: TOBIN MANUFACTURING, LLCInventors: John Tobin, John T. Mizulo, Christopher S. Shaw, Albert W. Shaw
-
Publication number: 20090082427Abstract: A cosmetic and therapeutic method for reducing human hair growth comprises selecting an area of skin from which reduced hair growth is desired and applying to the area of skin a composition comprising wortmannin in an amount effective to reduce hair growth.Type: ApplicationFiled: May 23, 2006Publication date: March 26, 2009Applicant: Reckitt Benckiser (UK) LimitedInventors: Frederic De La Torre, Desmond John Tobin
-
Publication number: 20090082473Abstract: A cosmetic and therapeutic method for reducing human hair growth comprises selecting an area of skin from which reduced hair growth is desired and applying to the area of skin a composition comprising resveratrol in an amount effective to reduce hair growth.Type: ApplicationFiled: May 23, 2006Publication date: March 26, 2009Applicant: Reckitt Benckiser (UK) LimitedInventors: Frederic De La Torre, Desmond John Tobin
-
Publication number: 20070175337Abstract: A beverage system for dispensing a homogeneous beverage is described. The beverage system has a mixing chamber with at least two mixing chamber housings for solvents of different temperatures. Beverage precursor provided to the mixing chamber is mixed via turbulent flow of solvents within the mixing chamber to yield a homogeneous beverage deplete of particles of undissolved precursor.Type: ApplicationFiled: January 31, 2006Publication date: August 2, 2007Inventors: David Fedorchak, John Tobin