Patents by Inventor John Toft
John Toft has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190200550Abstract: A method of making a media usable for instance in hydroponics. The method comprising mixing together three components, granulating the mixture and firing the granules formed, the first component is silica sand, the second component is mica granite sand, and the third component is a glass powder, with the firing taking place at a temperature such that the third component melts during firing.Type: ApplicationFiled: August 25, 2017Publication date: July 4, 2019Inventors: Victor Andrew HEATH, Michael John TOFT, Craig John TOFT
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Patent number: 10201501Abstract: There is provided use of a mixed metal compound in the manufacture of medicament for neutralizing or buffering stomach acid, wherein the mixed metal compound contains at least one trivalent metal selected from iron (III) and aluminum and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, wherein (A) the mixed metal compound is of formula (I): MII1-aMIIIaObAn?c.zH2O (I) where MII is the at least one bivalent metal; MIII is the at least one trivalent metal; An? at least one n-valent anion; 2+a=2b+?cn and ?cn<0.9a, and z is 2 or less, and/or (B) the mixed metal compound is provided in the form of a granular material comprising (i) at least 50% by weight, based on the weight of the granular material, of the mixed metal compound (ii) from 3 to 12% by weight, based on the weight of the granular material, of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: GrantFiled: July 24, 2008Date of Patent: February 12, 2019Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Maurice Sydney Newton, James David Morrison, Ruth Diane Pennel, Nigel Peter Rhodes, Alexis John Toft
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Patent number: 10155040Abstract: The present invention relates to mixed metal compounds having pharmaceutical activity, especially as phosphate binders. It also extends to methods of manufacture of those compounds, as well as to pharmaceutical compositions containing such compounds. It further relates to their pharmaceutical use. In particular, the present invention relates to use of compounds of Formula (I): MII1-aMIIIa wherein M? is at least one bivalent metal (i.e. with two positive charges); M1 is at least one trivalent metal (i.e. with three positive charges); and 1>a>0.4.Type: GrantFiled: October 15, 2008Date of Patent: December 18, 2018Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Maurice Sydney Newton, Alexis John Toft, Nigel Peter Rhodes
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Patent number: 9907816Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1-x.MIIIx(OH)2An?y.zH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MII is at least iron(III); An is at least one n-valent anion; x=?ny, 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: GrantFiled: January 22, 2015Date of Patent: March 6, 2018Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Ruth Diane Pennell, Maurice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20170106091Abstract: The present invention provides a composition comprising (i) a mixed metal compound containing at least one trivalent metal selected from iron (III) and aluminium and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, (ii) xanthan gum (iii) at least one of (a) polyvinyl pyrrolidone (b) locust bean gum (c) methyl cellulose wherein the composition has been irradiated with ionising radiation in an amount of at least 4kGy.Type: ApplicationFiled: December 29, 2016Publication date: April 20, 2017Inventors: Richard Jonathan Applewhite, Maurice Sydney Newton, Alexis John Toft
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Patent number: 9566302Abstract: The present invention provides a composition comprising (i) a mixed metal compound containing at least one trivalent metal selected from iron (lll) and aluminum and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, (ii) xanthan gum (iii) at least one of (a) polyvinyl pyrrolidone (b) locust bean gum (c) methyl cellulose wherein the composition has been irradiated with ionizing radiation in an amount of at least 4 kGy.Type: GrantFiled: February 3, 2011Date of Patent: February 14, 2017Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Richard Jonathan Applewhite, Alexis John Toft
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Publication number: 20160081331Abstract: The present invention relates to disinfecting and sterilising solutions containing glutaraldehyde. In particular, the invention provides solutions which are stabilised through the use of a unique combination of additives, including a bioflavonoid antioxidant (or other phenolic antioxidant) and an alkyl polyglucoside surfactant.Type: ApplicationFiled: December 2, 2015Publication date: March 24, 2016Applicant: GX LABS HOLDINGS LIMITEDInventor: John Toft
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Patent number: 9168270Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1-xMIIIx(OH)2An-y.ZH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MIII is at least iron(III); An- is at least one n-valent anion; x=?ny; 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: GrantFiled: January 30, 2007Date of Patent: October 27, 2015Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Ruth Diane Pennel, Maurice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20150132407Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1-x.MIIIx(OH)2An?y.zH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MII is at least iron(III); A is at least one n-valent anion; x=?ny, 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: ApplicationFiled: January 22, 2015Publication date: May 14, 2015Inventors: Ruth Diane Pennel, Maurice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20140066869Abstract: The present invention relates to an absorbent article, such as a sanitary towel, impregnated or coated with a deodorizing composition comprising a buffering component, a deodorizing agent, and an antimicrobial agent. Such deodorizing compositions help to reduce or eliminate odours emanating from the bodily fluids absorbed into the article during use.Type: ApplicationFiled: April 24, 2012Publication date: March 6, 2014Applicant: GX LABS HOLDINGS LIMITEDInventor: John Toft
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Publication number: 20130323325Abstract: The present invention provides a composition comprising (i) a mixed metal compound containing at least one trivalent metal selected from iron (lll) and aluminium and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, (ii) xanthan gum (iii) at least one of (a) polyvinyl pyrrolidone (b) locust bean gum (c) methyl cellulose wherein the composition has been irradiated with ionising radiation in an amount of at least 4 kGy.Type: ApplicationFiled: February 3, 2011Publication date: December 5, 2013Applicant: CYTOCHROMA DEVELOPMENT INC.Inventors: Richard Jonathan Applewhite, Maurice Sydney Newton, Alexis John Toft
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Publication number: 20130101674Abstract: The present invention relates to a biocidal coating composition comprising a biocide and an organofunctional silane oligomer which is distinct from the biocide. Such compositions are suitable for application to a substrate surface to provide long term disinfection on the surface of the substrate. The organofunctional silane oligomer prolongs the action of the biocide on the surface of the substrate, and provides improved surface-retention of the biocide.Type: ApplicationFiled: May 20, 2011Publication date: April 25, 2013Applicant: GX LABS HOLDINGS LIMITEDInventor: John Toft
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Publication number: 20130096202Abstract: The present invention relates to disinfecting and sterilising solutions containing glutaraldehyde. In particular, the invention provides solutions which are stabilised through the use of a unique combination of additives, including a bioflavonoid antioxidant (or other phenolic antioxidant) and an alkyl polyglucoside surfactant.Type: ApplicationFiled: June 24, 2011Publication date: April 18, 2013Applicant: GX LABS HOLDINGS LIMITEDInventor: John Toft
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Publication number: 20120093943Abstract: A substance for use as a medicament, comprises a solid mixed metal compound of formula (I): MII1-aMIIIaObAn?c.zH2O (I) where MII is at least one bivalent metal: MIII bis at least one trivalent metal; An? is at least one n-valent anion; 2+a=2b+?cn; and ?cn<0.9a. The substance may be made by heating at a temperature of from 200° C. to 600° C., preferably from 250° C. to 500° C. of a substance comprising a compound of formula (II): MII1-xMIIIx(OH)2An?y.mH2O (II) where MII is at least one bivalent metal; MIII is at least one trivalent metal; An? is at least one n-valent anion; x=?yn 0<x?0.5, 0<y?1 and 0<m?10.Type: ApplicationFiled: October 11, 2011Publication date: April 19, 2012Inventors: Maurice Sydney Newton, Nigel Peter Rhodes, Alexis John Toft
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Publication number: 20110064815Abstract: There is provided a silica for use to inhibit a protease. In particular there is provided a silica for treatment or prevention of a disease or condition associated with adverse protease activity or adverse proteolytic degradation within the gastrointestinal tract.Type: ApplicationFiled: April 23, 2009Publication date: March 17, 2011Inventors: Alexis John Toft, Peter William Dettmar, Johnathan Craig Richardson, Vicki Strugala
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Publication number: 20100215770Abstract: The present invention relates to mixed metal compounds having pharmaceutical activity, especially as phosphate binders. It also extends to methods of manufacture of those compounds, as well as to pharmaceutical compositions containing such compounds. It further relates to their pharmaceutical use. In particular, the present invention relates to use of compounds of Formula (I): MII1-aMIIIa wherein M is at least one bivalent metal (i.e. with two positive charges); M1 is at least one trivalent metal (i.e. with three positive charges); and 1>a>0.4.Type: ApplicationFiled: October 15, 2008Publication date: August 26, 2010Inventors: Maurice Sydney Newton, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20100203152Abstract: There is provided use of a mixed metal compound in the manufacture of medicament for neutralising or buffering stomach acid, wherein the mixed metal compound contains at least one trivalent metal selected from iron (III) and aluminium and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, wherein (A) the mixed metal compound is of formula (I): MII1-aMIIIaObAn-c.zH2O (I) where MII is the at least one bivalent metal; MIII is the at least one trivalent metal; An- at least one n-valent anion; 2+a=2b+?cn and ?cn<0.9a, and z is 2 or less, and/or (B) the mixed metal compound is provided in the form of a granular material comprising (i) at least 50% by weight, based on the weight of the granular material, of the mixed metal compound (ii) from 3 to 12% by weight, based on the weight of the granular material, of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: ApplicationFiled: July 24, 2008Publication date: August 12, 2010Applicant: Ineos Healthcare KimitedInventors: Maurice Sydney Newton, James David Morrison, Ruth Diane Pennell, Nigel Peter Phodes, Alexis John Toft
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Publication number: 20090317459Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1?xMIIIx(OH)2?n?y.ZH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MIII is at least iron(III); ?n? is at least one n-valent anion; x=?ny; 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: ApplicationFiled: January 30, 2007Publication date: December 24, 2009Inventors: Ruth Diane Pennel, Manrice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20080206358Abstract: A substance for use as a medicament, comprises a solid mixed metal compound of formula (I): MII1?aMIIIaObAn?c.zH2O (I) where MII is at least one bivalent metal: MIII bis at least one trivalent metal; An? is at least one n-valent anion; 2+a=2b+?cn; and ?cn<0.9a. The substance may be made by heating at a temperature of from 200° C. to 600° C. preferably from 250° C. to 500° C. of a substance comprising a compound of formula (II): MII1?xMIIIx(OH)2An?y.mH2O (II) where MII is at least one bivalent metal; MIII is at least one trivalent metal; An? is at least one n-valent anion; x=?yn 0<x?0.5, 0<y?1 and 0<m?10.Type: ApplicationFiled: February 6, 2006Publication date: August 28, 2008Applicant: Ineos Healthcare LimitedInventors: Maurice Sydney Newton, Nigel Peter Rhodes, Alexi John Toft
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Patent number: 5896724Abstract: A reinforcing strut for an overhead sectional door including a pair of oppositely directed feet for fastening the reinforcing strut to the overhead sectional door and a wall extending from an end of each of the feet with the walls overlying one another and fixed to one another.Type: GrantFiled: October 23, 1997Date of Patent: April 27, 1999Assignee: Kalford Pty. Ltd.Inventor: David John Tofts