Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: The present invention provides a snorkel having smaller respiratory dead space or volume. The snorkel includes a mouthpiece and a tube with an inhalation lumen and an exhalation lumen. A distal one-way inhalation valve is placed inside the inhalation lumen; and a distal one-way exhalation valve is placed inside the exhalation lumen. The invention also provides a method for reducing the volume of a respiratory dead space in a snorkel.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: The present invention provides a snorkel having smaller respiratory dead space or volume. The snorkel includes a mouthpiece and a tube with an inhalation lumen and an exhalation lumen. A distal one-way inhalation valve is placed inside the inhalation lumen; and a distal one-way exhalation valve is placed inside the exhalation lumen. The invention also provides a method for reducing the volume of a respiratory dead space in a snorkel.

Abstract: The present invention provides a snorkel having smaller respiratory dead space or volume. The snorkel includes a mouthpiece and a tube with an inhalation lumen and an exhalation lumen. A distal one-way inhalation valve is placed inside the inhalation lumen; and a distal one-way exhalation valve is placed inside the exhalation lumen. The invention also provides a method for reducing the volume of a respiratory dead space in a snorkel.

Abstract: The present invention provides a snorkel having smaller respiratory dead space or volume. The snorkel includes a mouthpiece and a tube with an inhalation lumen and an exhalation lumen. A distal one-way inhalation valve is placed inside the inhalation lumen; and a distal one-way exhalation valve is placed inside the exhalation lumen. The invention also provides a method for reducing the volume of a respiratory dead space in a snorkel.

Abstract: The present invention provides a building piece comprising a first wing, a second wing, and a flexible belt connecting said two wings. The first wing has a first front side and a first back side, and the second wing has a second front side and a second back side. At least two of the four sides each comprise a topographical profile or a landscape. In the present invention, the term “landscape” can be used interchangeably with the term “topographical profile”. The landscape on any one of the at least two sides can be reversibly interlocked, or is reversibly interlockable, to another one of the at least two sides.

Abstract: The present invention provides a building piece toy including a first container comprising a first cavity with a first opening, a second container comprising a second cavity with a second opening, and a flexible belt connecting said two containers. The container is tapered monotonously in all dimensions from the opening to the rest of the container's body. Many of the building pieces are interlockable to each other, so a player can create toys with a shape of human, animal, or plant such as lobster, butterfly, peacock and chicken.

Abstract: A modifiable boomerang comprises of a pair of wing blades which have a curved top surface and a flat bottom surface. The wings are connected together by a pivot bolt to form a boomerang whose angle can be adjusted to change the aerodynamics of the flying boomerang. A thrower can change the angle of a boomerang to change its flying pattern.

Abstract: The subject disclosure relates to ways to ensure vehicle network connectivity. In some aspects, a process of the technology includes steps for receiving local network measurement data including one or more connectivity metrics for at least one network provider (e.g., an ISP), and updating a geo-connectivity database using the received local network measurement data. In some aspects, the process can include additional steps for transmitting a geo-connectivity request to a remote Intelligent Vehicle Connectivity Analytics (IVCA) gateway, and for receiving a geo-connectivity reply from the remote IVCA gateway, the geo-connectivity reply including information regarding network availability for the at least one network provider along a vehicle path. Systems and machine-readable media are also provided.

Abstract: A vehicle is provided that includes a vehicle navigation system, a dialysis machine, and an interface providing an electrical communication between the dialysis machine and the vehicle navigation system. The dialysis machine is configured to perform a dialysis treatment on a patient while the vehicle is operating. The vehicle can be a car, a train, a plane, or another vehicle.

Abstract: A vehicle is provided that includes a vehicle navigation system, a dialysis machine, and an interface providing an electrical communication between the dialysis machine and the vehicle navigation system. The dialysis machine is configured to perform a dialysis treatment on a patient while the vehicle is operating. The vehicle can be a car, a train, a plane, or another vehicle.

Abstract: A vehicle is provided that includes a vehicle navigation system, a dialysis machine, and an interface providing an electrical communication between the dialysis machine and the vehicle navigation system. The dialysis machine is configured to perform a dialysis treatment on a patient while the vehicle is operating. The vehicle can be a car, a train, a plane, or another vehicle.

Abstract: An autonomous vehicle is provided that includes an autonomous vehicle control system, a dialysis machine, and an interface providing an electrical communication between the dialysis machine and the autonomous vehicle control system. The dialysis machine is configured to perform a dialysis treatment on a patient while the autonomous vehicle is under the control of the autonomous vehicle control system. A vehicle is also provided that includes a navigation system, a dialysis machine, and an interface between the navigation system and the dialysis machine. The vehicle can be a car, a train, a plane, or another vehicle.

Abstract: An autonomous vehicle is provided that includes an autonomous vehicle control system, a dialysis machine, and an interface providing an electrical communication between the dialysis machine and the autonomous vehicle control system. The dialysis machine is configured to perform a dialysis treatment on a patient while the autonomous vehicle is under the control of the autonomous vehicle control system. A vehicle is also provided that includes a navigation system, a dialysis machine, and an interface between the navigation system and the dialysis machine. The vehicle can be a car, a train, a plane, or another vehicle.