Abstract: This invention relates to nutrient and therapeutic compositions for treatment and prevention of symptoms and disease conditions associated with microangiopathy and macroangiopathy and to methods using the compositions. In particular, the invention relates to compositions useful in the treatment of diabetic retinopathy and nephropathy, to compositions useful in the treatment of other retinal disorders including macular degeneration and cataracts, to compositions useful in wound healing, to compositions useful for treatment and prevention of neuropathy, to compositions useful for treatment and prevention of cardiovascular disease and to compositions useful for the treatment and prevention of dental and periodontal disorders.

Abstract: This invention relates to nutrient and therapeutic compositions for treatment and prevention of symptoms and disease conditions associated with microangiopathy and macroangiopathy and to methods using the compositions. In particular, the invention relates to compositions useful in the treatment of diabetic retinopathy and nephropathy, to compositions useful in the treatment of other retinal disorders including macular degeneration and cataracts, to compositions useful in wound healing, to compositions useful for treatment and prevention of neuropathy, to compositions useful for treatment and prevention of cardiovascular disease and to compositions useful for the treatment and prevention of dental and periodontal disorders.

Abstract: A solid arrow shaft front extension portion or ferrule having a plurality of offset slots parallel to tangents to the shaft for replaceable and interchangeable devices or blades of general triangular or other shape held at their forward end in the slots by an interchangeable screw-in tip and at their rearward end by a deformable collar urged into locking the devices in position by screwing of the rear shank of the shaft extension or arrowhead into the front socket of the arrow shaft. If desired, between the collar and the end of the arrow shaft there may be provided one or more weight washers and/or a resilient locking washer for adjusting the angularity of the blades with respect to the nock at the rear of the arrow shaft.