Patents by Inventor John V. Napoleon

John V. Napoleon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REJUVENATION OF CAR T CELL
    Publication number: 20240148880
    Abstract: A payload of drug conjugated to a targeting ligand specifically designed to deliver to exhausted CAR T cells to rejuvenate these CAR T cells is provided herein. The targeted CAR T cells are modified with a fusion receptor which can bind to the targeting ligand and internalize the conjugated payload of drug to execute its regulatory function to exhausted CAR T cell.
    Type: Application
    Filed: December 21, 2023
    Publication date: May 9, 2024
    Inventors: Philip Stewart LOW, Boning Zhang, John V. Napoleon
  • REJUVENATION OF CAR T CELL
    Publication number: 20210308267
    Abstract: A payload of drug conjugated to a targeting ligand specifically designed to deliver to exhausted CART cells to rejuvenate these CAR T cells is provided herein. The targeted CAR T cells are modified with a fusion receptor which can bind to the targeting ligand and internalize the conjugated payload of drug to execute its regulatory function to exhausted CAR T cell.
    Type: Application
    Filed: July 21, 2019
    Publication date: October 7, 2021
    Inventors: Philip Stewart Low et al., Boning Zhang, John V. Napoleon