Abstract: For keyboards, the present invention provides a method of determining suitable letter arrangements, to create an arrangement that is both user-friendly and efficient. The letters in the preferred embodiment are in the familiar alphabetical order so they are easy to find, and their locations are easy to learn and retain. The alphabetical sequence goes from left to right, row by row from top to bottom, first for the left hand, then for the right hand, like reading the pages of a book. This arrangement optimizes efficiency and user-friendliness, maximizing the separation of the most commonly used pairs of letters into the faster, two-handed sequences, while providing a logical and easily recognized layout. The usual four punctuation marks are placed within the layout so as to enhance both of these qualities.