Abstract: A drill guide device for bone plate fixation, consisting of an elongated drill guide block having a longitudinal recess for receiving and positioning a bone plate having screw openings. The guide block has spaced openings axially aligned with the bone plate screw openings and containing removable drill guide bushings. The guide block is longitudinally slotted at its ends for adjustable attachment to clamp blocks carrying respective bone-engaging scissor clamp assemblies connected by tie rods. The tie rods have oppositely threaded ends which are threadedly engaged with the respective clamp blocks. The tie rods have hexagonal center portions shaped for driving engagement by a wrench. The scissor clamp assemblies have upstanding opposite top handle portions connected by clamping screws, each clamping screw being pivotally connected to one handle portion and extending through the opposite handle portion. The outer end portion of each clamping screw is provided with a clamping nut.