Abstract: Provided herein are compositions and method for treating and preventing skin damage In particular, provided herein re compositions that reverse, prevent and/or slow age-related skin damage.

Abstract: A system for transporting objects includes an endless belt to transport objects. Optically visible indicia may be associated with a position on the endless belt. Machine-detectable indicia correlated with the optically visible indicia may be associated with a substantially similar position on the endless belt as the optically visible indicia.

Abstract: A method for correlating optically visible objects with objects detectable through a non-invasive imaging system is described. The method includes conveying an object on a conveyer belt through the non-invasive imaging system. The conveyer belt can include optically visible indicia and machine-detectable indicia. The object and the machine-detectable indicia can be displayed on a display in communication with the non-invasive imaging system. The machine-detectable indicia viewed on the display can be correlated with the optically visible indicia on the conveyer belt after the object has exited the non-invasive imaging system to identify the object.

Abstract: Acne-affected skin has been found to be accompanied by the presence of matrix-degrading enzymes such as MMPs and neutrophil elastase, induction of neutrophils, and a reduction in procollagen biosynthesis. This invention treats scarring and inflammation accompanying acne by administering, topically or systemically, at least one of (i) an inhibitor of the matrix degrading enzymes and (ii) a cytokine inhibitor that alleviates inflammation and thus also alleviate neutrophil infiltration. Alleviating the matrix degradation and renormalizing procollagen biosynthesis allows for reduced inflammation and better natural repair of acne-affected skin. Inhibiting cytokines alleviates induction of MMPs in resident skin cells, and also alleviates inflammation with its concommitant induction of neutrophils from the blood stream bringing MMPs and elastase into the acne lesion.

Abstract: A restraint device includes a closable loop to circumscribe a wearer's limb and defining an inner opening having a plurality of sizes. An indicator scale is associated with the loop to indicate the size of the opening in a closed configuration. The size indicated by the indicator scale can be documented or recorded for future reference.

Abstract: UVB radiation of about 300-310 nm wavelength and UVA radiation of about 380-390 nm wavelength, each of which exists in solar light, induces MMPs (matrix metalloproteinases) in human skin that degrade the collagen of the dermal matrix. This degradation contributes to photoaging of human skin, which can be prevented by blocking these wavelengths of solar radiation. In contrast, diseases that result in the overproduction of collagen can be treated by exposing the affected with to radiation having wavelengths in those regions, for these wavelengths not only induce MMPs but also inhibit collagen biosynthesis. For lighter skinned people so affected, the UVA wavelengths are preferred because of the reduced amount of erythema, whereas dark skinned people can be treated with the UVB radiation because they generally do not suffer from erythema.

Abstract: Rosacea is treated with a composition comprising an antimicrobial and at least one of an anti-inflammatory and a non-retinoid inhibitor of at least one of NF-KB, AP-1, MMPs, adhesion molecules, TLRs, and CD14. The composition may further comprise a retinoid.

Abstract: Acne-affected skin has been found to be accompanied by the presence of matrix-degrading enzymes such as MMPs and neutrophil elastase, induction of neutrophils, and a reduction in procollagen biosynthesis. This invention treats scarring and inflammation accompanying acne by administering, topically or systemically, at least one of (i) an inhibitor of the matrix degrading enzymes and (ii) a cytokine inhibitor that alleviates inflammation and thus also alleviate neutrophil infiltration. Alleviating the matrix degradation and renormalizing procollagen biosynthesis allows for reduced inflammation and better natural repair of acne-affected skin. Inhibiting cytokines alleviates induction of MMPs in resident skin cells, and also alleviates inflammation with its concommitant induction of neutrophils from the blood stream bringing MMPs and elastase into the acne lesion.

Abstract: Photoaging of human skin, such as evidenced by the increased presence of matrix metalloproteinases after exposure to UV radiation, is prevented by pre-treating the skin with an inhibitor of epidermal growth factor receptor (EGF-R) prior to exposure. Such inhibitor are preferably natural, an example of which is genistein. Compositions used for such purposes preferably include an EGF-R as well as another MMP inhibitor, such as a retinoid.

Abstract: Acne-affected skin has been found to be accompanied by the presence of matrix-degrading enzymes such as MMPs and neutrophil elastase, induction of neutrophils, and a reduction in procollagen biosynthesis. This invention treats scarring and inflammation accompanying acne by administering, topically or systemically, at least one of (i) an inhibitor of the matrix degrading enzymes and (ii) a cytokine inhibitor that alleviates inflammation and thus also alleviate neutrophil infiltration. Alleviating the matrix degradation and renormalizing procollagen biosynthesis allows for reduced inflammation and better natural repair of acne-affected skin. Inhibiting cytokines alleviates induction of MMPs in resident skin cells, and also alleviates inflammation with its concommitant induction of neutrophils from the blood stream bringing MMPs and elastase into the acne lesion.

Abstract: Compositions and methods are provided for ameliorating various effects of UVA and UVB radiation, especially from the sun. The compositions include an ingredient that prevents photoaging from MED and subMED radiation, namely an MMP (matrix metalloproteinase) inhibitor, especially formulated for oral administration, and more especially formulated for controlled-release so as to provide the MMP inhibitor when MMP induction (including upstream signalling molecules like c-JUN, and/or MMPs like stromelysin) is most prevalent.

Abstract: A composition for relief of symptoms of colds and influenza, containing, by weight, about 80-88% olive leaf extract powder containing oleuropein, about 5-10% neem leaf powder and up to about 8% of a homeopathic blend for symptom relief which preferably comprises aconitum napelius, belladonna, eupatorium perfoliatum, gelsemium sempervirens, Echinacea angustifolia and ferrum phosphoricum.

Abstract: A composition for relief of symptoms of colds and influenza, containing, by weight, about 80-88% olive leaf extract powder containing oleuropein, about 5-10% neem leaf powder and up to about 8% of a homeopathic blend for symptom relief which preferably comprises aconitum napelius, belladonna, eupatorium perfoliatum, gelsemium sempervirens, Echinacea angustifolia and ferrum phosphoricum.

Abstract: There is disclosed a cushion of flexible plastic sheet material adapted to be filled with water or other liquid wherein the interior space is divided into at least two compartments, one of which is annular, the shape being particularly adapted to provide a cushion with firm, comfortable support while at the same time being simple and inexpensive to manufacture. Separate filler openings are provided for the two compartments which permits their being filled independently, to different degrees if desired. The cushion is preferably provided with a textile fabric cover which is removable for storage and shipping.

Abstract: There is disclosed a dual blade wiper for a windshield wiper or squeegee in which the wiper is separated along its length into two blade portions except for its ends; at the ends the blade is not separated but at least one of the ends has a slot which communicates with the space between the 2 blade portions; the blade edges are preferably rounded on the ends rather than having the conventional tapered configuration. The construction of the blade, the flexure characteristics of the material and the forces present during motion of the wiper cause the blade portions to separate and come together in the reciprocating action of the windshield wiper, thereby drawing water or moisture into the space between the blade portions and ejecting it from the slot communicating with the space between the blade portions.