Patents by Inventor John W. Chen

John W. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Highly efficient myeloperoxidase activatable imaging agents
    Patent number: 12655162
    Abstract: Provided herein are compounds useful as imaging agents. Exemplary compounds provided herein are useful as myeloperoxidase imaging agents using magnetic resonance or nuclear imaging techniques. Methods for preparing the compounds provided herein and diagnostic methods using the compounds are also provided.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: June 16, 2026
    Assignee: The General Hospital Corporation
    Inventors: John W. Chen, Cuihua Wang
  • Myeloperoxidase imaging agents
    Patent number: 12570606
    Abstract: Provided herein are compounds useful as imaging agents. Exemplary compounds provided herein are useful as myeloperoxidase imaging agents using positron emission tomography or fluorescence imaging techniques. Methods for preparing the compounds provided herein and diagnostic methods using radiolabeled arid unlabeled compounds are also provided.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: March 10, 2026
    Assignee: The General Hospital Corporation
    Inventors: John W. Chen, Cuihua Wang, Edmund J. Keliher
  • Highly Efficient Myeloperoxidase Activatable Imaging Agents
    Publication number: 20230124429
    Abstract: Provided herein are compounds useful as imaging agents. Exemplary compounds provided herein are useful as myeloperoxidase imaging agents using magnetic resonance or nuclear imaging techniques. Methods for preparing the compounds provided herein and diagnostic methods using the compounds are also provided.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 20, 2023
    Inventors: John W. Chen, Cuihua Wang
  • Myeloperoxidase Imaging Agents
    Publication number: 20220340524
    Abstract: Provided herein are compounds useful as imaging agents. Exemplary compounds provided herein are useful as myeloperoxidase imaging agents using positron emission tomography or fluorescence imaging techniques. Methods for preparing the compounds provided herein and diagnostic methods using radiolabeled arid unlabeled compounds are also provided.
    Type: Application
    Filed: April 29, 2022
    Publication date: October 27, 2022
    Inventors: John W. Chen, Cuihua Wang, Edmund J. Keliher
  • Myeloperoxidase imaging agents
    Patent number: 11352326
    Abstract: Provided herein are compounds useful as imaging agents. Exemplary compounds provided herein are useful as myeloperoxidase imaging agents using positron emission tomography or fluorescence imaging techniques. Methods for preparing the compounds provided herein and diagnostic methods using radiolabeled and unlabeled compounds are also provided.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: June 7, 2022
    Assignee: The General Hospital Corporation
    Inventors: John W. Chen, Cuihua Wang, Edmund J. Keliher
  • Myeloperoxidase Imaging Agents
    Publication number: 20190315689
    Abstract: Provided herein are compounds useful as imaging agents. Exemplary compounds provided herein are useful as myeloperoxidase imaging agents using positron emission tomography or fluorescence imaging techniques. Methods for preparing the compounds provided herein and diagnostic methods using radiolabeled and unlabeled compounds are also provided.
    Type: Application
    Filed: November 16, 2017
    Publication date: October 17, 2019
    Inventors: John W. Chen, Cuihua Wang, Edmund J. Keliher
  • Imaging of enzyme activity
    Patent number: 8153784
    Abstract: This invention relates to biochemistry and magnetic resonance imaging.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: April 10, 2012
    Assignee: The General Hospital Corporation
    Inventors: Alexei Bogdanov, John W. Chen, Ralph Weissleder, Manel Querol