Patents by Inventor John W. Chu
John W. Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970479Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.Type: GrantFiled: October 24, 2019Date of Patent: April 30, 2024Assignees: Merck Sharp & Dohme LLC, MSD R&D (China) Co. LTD.Inventors: John J. Acton, III, Melissa Egbertson, Xiaolei Gao, Scott T. Harrison, Timothy J. Henderson, Michael Man-Chu Lo, Robert D. Mazzola, Jr., Zhaoyang Meng, James Mulhearn, Vanessa L. Rada, Jeffrey W. Schubert, Oleg B. Selyutin, David M. Tellers, Ling Tong, Fengqi Zhang, Jianming Bao, Chunsing Li
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Patent number: 10017708Abstract: This disclosure relates to a composition for use as an additive for fuels and lubricants including a reductive amination product of a vinyl terminated macromonomer (VTM) based aldehyde. Optionally aldehyde is reacted with the amino compound under condensation conditions sufficient to give an imine intermediate, and the imine intermediate is reacted under hydrogenation conditions sufficient to give the composition. The aldehyde is formed by reacting a VTM under hydroformylation conditions sufficient to form the aldehyde. A reductive amination method for making a composition for use as an additive for fuels and lubricants. The method includes reacting a VTM based aldehyde with an amino compound containing at least one —NH— group under condensation conditions sufficient to give an imine intermediate, and reacting the imine intermediate under hydrogenation conditions sufficient to give said composition. The aldehyde is formed by reacting a VTM under hydroformylation conditions sufficient to form the aldehyde.Type: GrantFiled: September 4, 2013Date of Patent: July 10, 2018Assignee: ExxonMobil Chemical Patents Inc.Inventors: Abhimanyu Onkar Patil, John W. Chu, Satish Bodige, Liehpao Oscar Farng, Donna Jean Crowther, Man Kit Ng, Patrick Brant, Kathryn L. Peretti
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Publication number: 20160368844Abstract: In a process for producing a mixture of cyclohexanone and cyclohexanol, a feed comprising cyclohexanone is contacted with hydrogen in the presence of a hydrogenation catalyst under hydrogenation conditions effective to convert part of the cyclohexanone in the feed into cyclohexanol and thereby produce a hydrogenation product containing cyclohexanone and cyclohexanol. A mixture of cyclohexanone and cyclohexanol is then obtained from the hydrogenation product.Type: ApplicationFiled: March 7, 2014Publication date: December 22, 2016Inventors: Jihad M. Dakka, Charles M. Smith, Kun Wang, Francisco M. Benitez, Roberto Garcia, John W. Chu, Keith H. Kuechler, Chuansheng Bai
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Publication number: 20140213834Abstract: Provided is a polyalphaolefin (PAO) fluid including a polymer of one or more C8 to C12 alphaolefin monomers. The PAO has a viscosity (Kv100) from 300 to 900 cSt at 100° C.; a viscosity index (VI) greater than 250; a pour point (PP) less than ?25° C.; a molecular weight distribution (Mw/Mn) less than 2.0 as synthesized; a residual unsaturation (Bromine Number) less than 2.0; and a glass transition temperature Tg less than ?60° C. The PAO also has no crystallization peak as measured by differential scanning calorimetry and high thermal stability. A process to make and use the PAOs, including those having any combination of characteristics above is also provided. The PAOs are useful as synthetic base stocks and co-base stocks in lubricating oils, e.g., industrial lubes.Type: ApplicationFiled: January 28, 2013Publication date: July 31, 2014Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: ABHIMANYU O. PATIL, SATISH BODIGE, SHUJI LUO, JOHN W. CHU, KEVIN STAVENS, BRUCE A. HARRINGTON
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Publication number: 20140087985Abstract: This disclosure relates to a composition for use as an additive for fuels and lubricants including a reductive amination product of a vinyl terminated macromonomer (VTM) based aldehyde. Optionally aldehyde is reacted with the amino compound under condensation conditions sufficient to give an imine intermediate, and the imine intermediate is reacted under hydrogenation conditions sufficient to give the composition. The aldehyde is formed by reacting a VTM under hydroformylation conditions sufficient to form the aldehyde. A reductive amination method for making a composition for use as an additive for fuels and lubricants. The method includes reacting a VTM based aldehyde with an amino compound containing at least one —NH— group under condensation conditions sufficient to give an imine intermediate, and reacting the imine intermediate under hydrogenation conditions sufficient to give said composition. The aldehyde is formed by reacting a VTM under hydroformylation conditions sufficient to form the aldehyde.Type: ApplicationFiled: September 4, 2013Publication date: March 27, 2014Applicant: ExxonMobil Research and Engineering CompanyInventors: Abhimanyu Onkar Patil, John W. Chu, Satish Bodige, Liehpao Oscar Farng, Donna Jean Crowther, Man Kit Ng, Patrick Brant, Kathryn L. Peretti
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Patent number: 8614277Abstract: Isotactic polypropylene ethylene-propylene copolymer blends and in-line processes for producing. The blends may have between 1 and 50 wt % of isotactic polypropylene with a melt flow rate of between 0.5 and 20,000 g/10 min and a melting peak temperature of 145° C. or higher, and wherein the difference between the DSC peak melting and the peak crystallization temperatures is less than or equal to 0.5333 times the melting peak temperature minus 41.333° C., and between 50 and 99 wt % of ethylene-propylene copolymer including between 10 wt % and 20 wt % randomly distributed ethylene with a melt flow rate of between 0.5 and 20,000 g/10 min, wherein the copolymer is polymerized by a bulk homogeneous polymerization process, and wherein the total regio defects in the continuous propylene segments of the copolymer is between 40 and 150% greater than a copolymer of equivalent melt flow rate and wt % ethylene polymerized by a solution polymerization process.Type: GrantFiled: February 13, 2012Date of Patent: December 24, 2013Assignee: ExxonMobil Research and Engineering CompanyInventors: Gabor Kiss, Patrick Brant, Robert Patrick Reynolds, Jr., Aspy K. Mehta, Manika Varma-Nair, John W. Chu, Steven P. Rucker
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Patent number: 8445620Abstract: Provided are elastic propylene-alpha olefin blocky copolymers. In one form, the elastic propylene-alpha olefin blocky copolymer includes an ?-olefin content from 12 to 25 wt % and having a propylene crystallinity less than 30 J/g, a Tm <100° C. and a Tg >?45° C., wherein said copolymer has blocky propylene segments with r1r2 greater than 1.5, and a process for producing such copolymer.Type: GrantFiled: August 4, 2011Date of Patent: May 21, 2013Assignee: ExxonMobil Research and Engineering CompanyInventors: Andy Haishung Tsou, Gabor Kiss, Robert Patrick Reynolds, Jr., John W. Chu, Alan Anthony Galuska, Patrick Brant, Donald Andrew Winesett
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Patent number: 8410230Abstract: Provided are methods of producing polymers with broadened molecular weight and/or composition distribution in a continuous homogeneous polymerization system utilizing reactor temperature gradients, reactor polymer concentration gradients, monomer concentration gradients, catalyst concentration gradients, and combinations thereof in the polymerization reactor. Such methods are particularly suitable when utilizing metallocene catalysts and other single-site catalysts, which generally produce polymers with narrow molecular weight and composition distribution.Type: GrantFiled: April 18, 2011Date of Patent: April 2, 2013Assignee: ExxonMobil Research and Engineering CompanyInventors: Gabor Kiss, Robert Patrick Reynolds, Jr., John W. Chu, Patrick Brant, James Richardson Lattner
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Patent number: 8399586Abstract: A process for feeding ethylene into a polymerization system includes providing a low-pressure ethylene stream, one or more low-pressure C3 to C20 monomer streams, an optional low-pressure inert solvent/diluent stream, and one or more reactors; metering the low-pressure ethylene stream, the one or more low-pressure C3 to C20 monomer streams, and the optional low-pressure inert solvent/diluent stream; blending the metered low-pressure ethylene stream, the metered one or more low-pressure C3 to C20 monomer streams, and the metered low-pressure optional inert solvent/diluent stream to form an ethylene-carrying low-pressure blended liquid feed stream; pressurizing the ethylene-carrying low-pressure blended liquid feed stream to the polymerization system pressure with one or more high-pressure pumps to thrm an ethylene-carrying high-pressure blended reactor feed stream; and feeding the ethylene-carrying high-pressure blended reactor feed stream to the one or more reactors.Type: GrantFiled: September 3, 2009Date of Patent: March 19, 2013Assignee: ExxonMobil Research and Engineering CompanyInventors: Gabor Kiss, Robert Patrick Reynolds, Jr., John W. Chu, James Richardson Lattner, Gary D. Mohr
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Publication number: 20130035442Abstract: Provided are elastic propylene-alpha olefin blocky copolymers. In one form, the elastic propylene-alpha olefin blocky copolymer includes an ?-olefin content from 12 to 25 wt % and having a propylene crystallinity less than 30 J/g, a Tm <100° C. and a Tg >?45° C., wherein said copolymer has blocky propylene segments with r1r2 greater than 1.5, and a process for producing such copolymer.Type: ApplicationFiled: August 4, 2011Publication date: February 7, 2013Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Andy Haishung Tsou, Gabor Kiss, Robert Patrick Reynolds, JR., John W. Chu, Alan Anthony Galuska, Patrick Brant, Donald Andrew Winesett
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Patent number: 8318875Abstract: This invention relates to processes for producing an isotactic propylene homopolymer having more than 15 and less than 100 regio defects (sum of 2,1-erythro and 2,1-threo insertions and 3,1-isomerizations) per 10,000 propylene units; a weight-averaged molecular weight of 35000 g/mol or more; a peak melting temperature of greater than 149° C.; an mmmm pentad fraction of 0.85 or more; a heat of fusion of 80 J/g or more; and a peak melting temperature minus peak crystallization temperature (Tmp?Tcp) of less than or equal to (0.907 times Tmp) minus 99.64 (Tmp?Tcp<(0.907×Tmp)?99.64), as measured in ° C. on the homopolymer having 0 wt % nucleating agent.Type: GrantFiled: November 4, 2008Date of Patent: November 27, 2012Assignee: Exxonmobil Chemical Patents Inc.Inventors: Aspy K. Mehta, Manika Varma-Nair, Gabor Kiss, Robert P. Reynolds, John W. Chu, Steven P. Rucker
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Publication number: 20120225998Abstract: Isotactic polypropylene ethylene-propylene copolymer blends and in-line processes for producing. The blends may have between 1 and 50 wt % of isotactic polypropylene with a melt flow rate of between 0.5 and 20,000 g/10 min and a melting peak temperature of 145° C. or higher, and wherein the difference between the DSC peak melting and the peak crystallization temperatures is less than or equal to 0.5333 times the melting peak temperature minus 41.333° C., and between 50 and 99 wt % of ethylene-propylene copolymer including between 10 wt % and 20 wt % randomly distributed ethylene with a melt flow rate of between 0.5 and 20,000 g/10 min, wherein the copolymer is polymerized by a bulk homogeneous polymerization process, and wherein the total regio defects in the continuous propylene segments of the copolymer is between 40 and 150% greater than a copolymer of equivalent melt flow rate and wt % ethylene polymerized by a solution polymerization process.Type: ApplicationFiled: February 13, 2012Publication date: September 6, 2012Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Gabor Kiss, Patrick Brant, Robert Patrick Reynolds, JR., Aspy K. Mehta, Manika Varma-Nair, John W. Chu, Steven P. Rucker
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Patent number: 8247495Abstract: Elastomeric polymer blends and processes for their production are described. Specifically, the polymer blends comprise a first polymer and a second polymer, where the first polymer comprises from about 70 wt % to about 90 wt % units derived from propylene and from about 10 wt % to about 30 wt % units derived from ethylene and/or a C4-C10 alpha-olefin, and the second polymer comprises from about 88 wt % to about 98 wt % units derived from propylene and from about 2 wt % to about 12 wt % units derived from ethylene and/or a C4-C10 alpha-olefin. The elastomeric polymer blends are further characterized by having two or more of the following properties: an overall propylene content of between about 75 wt % and about 90 wt %, a melting point between about 110° C. and about 145° C., a Vicat softening point greater than about 45° C.Type: GrantFiled: January 27, 2011Date of Patent: August 21, 2012Assignee: ExxonMobil Chemical Patents Inc.Inventors: Rainer Kolb, John W. Chu, Gabor Kiss, Robert P. Reynolds, Jr., Jean-Roch Schauder, Thomas T. Sun
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Patent number: 8173748Abstract: Provided is a heat-seal resin. The resin includes 5 wt % to 95 wt % of a first copolymer and 95 wt % to 5 wt % of a second copolymer based on the total weight of the resin. The first copolymer and the second copolymer together are 90 wt % or more of the total weight of the resin. The first copolymer includes a first monomer of an alphaolefin of 2 to 4 carbon atoms and a second monomer selected from a second monomer of an alphaolefin of 2 to 8 carbon atoms. The first monomer and the second monomer of the first copolymer are different. The first copolymer has an MFR of from 5 to 1000 g/10 minutes and a Tfm of 66° C. to 80° C. The second copolymer includes a first monomer of an alphaolefin of 2 to 4 carbon atoms and a second monomer selected from a second monomer of an alphaolefin of 2 to 8 carbon atoms. The first monomer and the second monomer of the second copolymer are different. The second copolymer has an MFR of from 0.5 to 5 g/10 minutes and a Tfm of 45° C. to 66° C.Type: GrantFiled: December 17, 2010Date of Patent: May 8, 2012Assignee: ExxonMobil Research and Engineering CompanyInventors: David John Lohse, Thomas Tungshi Sun, Aspy K. Mehta, Gabor Kiss, Robert Patrick Reynolds, Jr., John W. Chu, Manika Varma-Nair
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Patent number: 8138269Abstract: Isotactic polypropylene ethylene-propylene copolymer blends and in-line processes for producing them. The blends may have between 1 and 50 wt % of isotactic polypropylene with a melt flow rate of between 0.5 and 20,000 g/10 min and a melting peak temperature of 145° C. or higher, and wherein the difference between the DSC peak melting and the peak crystallization temperatures is less than or equal to 0.5333 times the melting peak temperature minus 41.333° C., and between 50 and 99 wt % of ethylene-propylene copolymer including between 10 wt % and 20 wt % randomly distributed ethylene with a melt flow rate of between 0.5 and 20,000 g/10 min, wherein the copolymer is polymerized by a bulk homogeneous polymerization process, and wherein the total regio defects in the continuous propylene segments of the copolymer is between 40 and 150% greater than a copolymer of equivalent melt flow rate and wt % ethylene polymerized by a solution polymerization process.Type: GrantFiled: December 18, 2008Date of Patent: March 20, 2012Assignee: ExxonMobil Research and Engineering CompanyInventors: Gabor Kiss, Patrick Brant, Robert Patrick Reynolds, Jr., Aspy K. Mehta, Manika Varma-Nair, John W. Chu, Steven P. Rucker
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Publication number: 20110207888Abstract: Elastomeric polymer blends and processes for their production are described. Specifically, the polymer blends comprise a first polymer and a second polymer, where the first polymer comprises from about 70 wt % to about 90 wt % units derived from propylene and from about 10 wt % to about 30 wt % units derived from ethylene and/or a C4-C10 alpha-olefin, and the second polymer comprises from about 88 wt % to about 98 wt % units derived from propylene and from about 2 wt % to about 12 wt % units derived from ethylene and/or a C4-C10 alpha-olefin. The elastomeric polymer blends are further characterized by having two or more of the following properties: an overall propylene content of between about 75 wt % and about 90 wt %, a melting point between about 110° C. and about 145° C., a Vicat softening point greater than about 45° C.Type: ApplicationFiled: January 27, 2011Publication date: August 25, 2011Inventors: Rainer Kolb, John W. Chu, Gabor Kiss, Robert P. Reynolds, JR., Jean-Roch Schauder, Thomas T. Sun
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Publication number: 20110196115Abstract: Provided are methods of producing polymers with broadened molecular weight and/or composition distribution in a continuous homogeneous polymerization system utilizing reactor temperature gradients, reactor polymer concentration gradients, monomer concentration gradients, catalyst concentration gradients, and combinations thereof in the polymerization reactor. Such methods are particularly suitable when utilizing metallocene catalysts and other single-site catalysts, which generally produce polymers with narrow molecular weight and composition distribution.Type: ApplicationFiled: April 18, 2011Publication date: August 11, 2011Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Gabor Kiss, Robert Patrick Reynolds, JR., John W. Chu, Patrick Brant, James Richardson Lattner
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Publication number: 20110196116Abstract: Provided are methods of producing polymers with broadened molecular weight and/or composition distribution in a continuous homogeneous polymerization system utilizing reactor temperature gradients, reactor polymer concentration gradients, monomer concentration gradients, catalyst concentration gradients, and combinations thereof in the polymerization reactor. Such methods are particularly suitable when utilizing metallocene catalysts and other single-site catalysts, which generally produce polymers with narrow molecular weight and composition distribution.Type: ApplicationFiled: April 18, 2011Publication date: August 11, 2011Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Gabor Kiss, Robert Patrick Reynolds, JR., John W. Chu, Patrick Brant, James Richardson Lattner
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Patent number: 7939610Abstract: Provided are methods of producing polymers with broadened molecular weight and/or composition distribution in a continuous homogeneous polymerization system utilizing reactor temperature gradients, reactor polymer concentration gradients, monomer concentration gradients, catalyst concentration gradients, and combinations thereof in the polymerization reactor. Such methods are particularly suitable when utilizing metallocene catalysts and other single-site catalysts, which generally produce polymers with narrow molecular weight and composition distribution.Type: GrantFiled: May 19, 2009Date of Patent: May 10, 2011Assignee: ExxonMobil Research and Engineering CompanyInventors: Gabor Kiss, Robert Patrick Reynolds, Jr., John W. Chu, Patrick Brant, James Richardson Lattner
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Patent number: 7928162Abstract: A process for fluid phase in-line blending of plasticized polymers is provided.Type: GrantFiled: September 9, 2008Date of Patent: April 19, 2011Assignee: ExxonMobil Research and Engineering CompanyInventors: Gabor Kiss, Alan Anthony Galuska, Robert Patrick Reynolds, Jr., John W. Chu, Bryan R. Chapman, Patrick Brant, Sudhin Datta