Patents by Inventor John W. Combs

John W. Combs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4812294
    Abstract: A specimen preparation unit having a plurality of interconnected compartments is automatically loaded onto a centrifuge rotor arm at a first rotor position. Each rotor arm has two indexing means for independently rotating the unit about either or both of two axes orthogonal to each other and to the rotor arm. The orientation of the unit with respect to the centrifugal force vector is changed in a predetermined manner so as to cause fluid flow between desired compartments even under conditions of microgravity. The unit is centrifuged in at least two different orientations with respect to the centrifugal force vector. As the fluids move between compartments, the specimen is prepared. After the multistep preparation process is completed, the unit is rotated to another rotor position at which the prepared specimen and/or the entire unit is removed. The centrifugal processing unit is capable of processing a plurality of specimen preparation unit in the same or a different manner.
    Type: Grant
    Filed: March 2, 1987
    Date of Patent: March 14, 1989
    Assignee: Automated Diagnostic Systems, Inc.
    Inventor: John W. Combs
  • Patent number: 4207554
    Abstract: Cells are automatically classified and analyzed by staining a measured amount of a specimen with a material which is adapted to fluoresce when illuminated; preparing a slide containing the stained specimen; illuminating the slide with light of successively changing wavelengths to measure the presence of the fluorescent response at each of the predetermined wavelengths to determine the constituents of the specimen.The detected constituents are automatically focused and scanned by a microscope having a capability of locating the constituent of interest, determining its size, shape and texture to thereby provide information as to the type, count and the like to enable a detailed analysis of the specimen.
    Type: Grant
    Filed: August 24, 1978
    Date of Patent: June 10, 1980
    Assignee: Med-El Inc.
    Inventors: Jerome B. Resnick, John W. Combs
  • Patent number: 4125828
    Abstract: Cells are automatically classified and analyzed by staining a measured amount of a specimen with a material which is adapted to fluoresce when illuminated; preparing a slide containing the stained specimen; illuminating the slide with light of successively changing wavelengths to measure the presence of the fluorescent response at each of the predetermined wavelengths to determine the constituents of the specimen.The detected constituents are automatically focused and scanned by a microscope having a capability of locating the constituent of interest, determining its size, shape and texture to thereby provide information as to the type, count and the like to enable a detailed analysis of the specimen.
    Type: Grant
    Filed: July 17, 1975
    Date of Patent: November 14, 1978
    Assignee: Med-El Inc.
    Inventors: Jerome B. Resnick, John W. Combs