Patents by Inventor John W. D. Eveleigh

John W. D. Eveleigh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoassays and nucleic acid assays with liquid exchange supports
    Patent number: 5306615
    Abstract: Immunoassays and nucleic acid assays are provided along with liquid perfluorocarbon supports utilized in these methods. The support is based on an inert perfluorocarbon carrier with ligands or binders for the ligands attached to its surface through a highly fluorinated isocyanate anchor group.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: April 26, 1994
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Julian P. Breillatt, Jr., John W. d. Eveleigh
  • Liquid perfluorocarbon supports useful as liquid affinity supports
    Patent number: 5276146
    Abstract: Liquid perfluorocarbon supports useful as liquid affinity supports are provided. The support is based on an inert perfluorocarbon carrier with ligands or binders for the ligands attached to its surface through a highly fluorinated isocyanate anchor group.
    Type: Grant
    Filed: September 17, 1991
    Date of Patent: January 4, 1994
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Julian P. Breillatt, Jr., John W. D. Eveleigh
  • Immobilization of biomolecules on perfluorocarbon surfaces
    Patent number: 5270193
    Abstract: Biomolecules such as a ligand or binder for the ligand are securely but reversibly attached to a perfluorocarbon carrier with a water soluble polymer, a perfluorocarbon anchoring group and optionally a linker group. The order of steps for carrying out the attachment can vary. For example, the biomolecule is covalently attached to the polymer followed by covalently attaching the anchoring group and attaching the resultant product to the carrier. Alternatively, the anchoring group is covalently attached to the polymer followed by attaching the resultant product to the carrier and then covalently attaching a biomolecule to the polymer. The polymer may be starch, dextran, agarose, polyethylene glycol or polyvinyl alcohol. An attached ligand or binder for the ligand is useful in affinity separations and immunoassays.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: December 14, 1993
    Assignee: E. I. DuPont de Nemours and Company
    Inventor: John W. D. Eveleigh
  • Preparation of liquid affinity supports for bioaffinity an ion exchange separations
    Patent number: 5268307
    Abstract: Methods for preparing liquid supports utilized in bioaffinity and ion-exchange separation methods and provided. The support is based on an inert carrier with ligands or binders for ligands attached through its surface through a highly fluorinated isocyanate anchor group. The use of such supports in capturing neutral and charged target molecules from samples and in analytical applications are also provided.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: December 7, 1993
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Julian P. Breillatt, Jr., John W. D. Eveleigh
  • Process for preparing solid perfluorocarbon polymer supports having attached perfluorocarbon-substituted ligand or binder
    Patent number: 5158880
    Abstract: A process for preparing solid perfluorocarbon polymer supports permitting uniform and secure attachment of perfluorocarbon-substituted ligands or binders to carriers is provided utilizing pretreatment of the carriers with water miscible organic solvents.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: October 27, 1992
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: John W. D. Eveleigh