Patents by Inventor John W. Gaiser
John W. Gaiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9924991Abstract: Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.Type: GrantFiled: March 15, 2014Date of Patent: March 27, 2018Assignee: Mederi Therapeutics, Inc.Inventors: Scott H. West, David Huynh, John W. Gaiser
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Publication number: 20170367757Abstract: Systems and methods deploy a therapeutic or diagnostic element into contact with a body tissue region. The systems and methods can sense position of the therapeutic or diagnostic element relative to a targeted tissue region without direct or indirect visualization, by sensing fluid pressure in a fluid path having an outlet located at or near the therapeutic or diagnostic element. The systems and methods can also inflate the therapeutic or diagnostic element during use, while taking steps to avoid over-inflation and/or while dynamically monitoring the pressure conditions within the expanded element.Type: ApplicationFiled: August 4, 2017Publication date: December 28, 2017Applicant: Mederi Therapeutics IncInventors: ROBIN BEK, John W. Gaiser, Scott West, Patrick Rimroth
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Patent number: 9844406Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.Type: GrantFiled: November 30, 2014Date of Patent: December 19, 2017Assignee: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley, Scott H. West, Jay Qin, Peter H. Muller
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Patent number: 9737360Abstract: Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.Type: GrantFiled: April 20, 2014Date of Patent: August 22, 2017Assignee: Mederi Therapeutics, Inc.Inventors: Scott H. West, John W. Gaiser, Robin Bek, David S. Utley, Patrick Rimroth
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Publication number: 20170189112Abstract: Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.Type: ApplicationFiled: March 18, 2017Publication date: July 6, 2017Applicant: Mederi Therapeutics, Inc.Inventors: Scott H. West, John W. Gaiser, Robin Bek, David S. Utley, Patrick Rimroth
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Patent number: 9675403Abstract: A device for treating a tissue region is supplied with a separate usage key card. The usage key card comprises a storage medium, which is formatted to contain an identification code unique to the usage key card. The usage key card is adapted to be read by a remote reader, to download the identification code for processing by a controller for the device. Processing of the identification code by the controller either enables or disables operation of the device according to prescribed criteria. A viewable image is generated on a display screen that changes in response to processing of the identification code.Type: GrantFiled: September 21, 2014Date of Patent: June 13, 2017Assignee: Mederi Therapeutics, Inc.Inventors: Jay Qin, Robin Bek, John W. Gaiser, David S. Utley
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Patent number: 9675409Abstract: Systems and methods are provided for positioning and stabilizing an external instrument during insertion of the instrument through the oral cavity (e.g., insertion of a catheter through the oral cavity and into the esophagus or cardia for treatment of gastroesophageal reflux disease (GERD)). The systems and methods provide a gripping tool for association with a bite block, capable of selectively moving between an open position in which the instrument may be inserted or removed, and a closed position in which the external instrument is held in a fixed position.Type: GrantFiled: January 19, 2014Date of Patent: June 13, 2017Assignee: Mederi Therapeutics, Inc.Inventors: Scott West, David S. Utley, John W. Gaiser
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Patent number: 9539052Abstract: An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.Type: GrantFiled: October 25, 2014Date of Patent: January 10, 2017Assignee: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley, Jay J. Qin
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Publication number: 20160074109Abstract: A family of barrel structures is provided in a kit. Each barrel structure is differently sized and configured for advancement into anal canals of different anatomic morphologies. Instructions are provided for using the barrel structures to treat an individual. The instructions instruct assessing an anatomic morphology of an anal canal of an individual to be treated and selecting one of the barrel structures based upon the assessed anatomic morphology. Each barrel structure carries an electrode sized and configured to be coupled to a source of tissue ablation energy to be applied through the electrode to form a lesion. Each barrel structure includes a transparent side wall visualized by a direct line of sight from an end portion of the first barrel structure. The instructions instruct inserting the selected barrel structure into the anal canal and visualizing by the direct line of sight through the transparent side wall of the selected barrel structure the dentate line and the targeted tissue region.Type: ApplicationFiled: November 27, 2015Publication date: March 17, 2016Applicant: Mederi Therapeutics, Inc.Inventors: Scott H. West, John W. Gaiser, Patrick Rimroth, Larry C. Heaton
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Publication number: 20160022357Abstract: A sphincter tissue region is treated using a support structure sized for advancement into the anal canal. At least one electrode is carried by the structure. A mechanism is coupled to the electrode to move the electrode between a first position retracted in the support structure and a second position extended from the support structure through surface tissue to penetrate a subsurface tissue region at or near a sphincter in the anal canal. A cable is coupled to the electrode to conduct energy for application by the electrode to form a lesion in the subsurface tissue region.Type: ApplicationFiled: August 17, 2015Publication date: January 28, 2016Applicant: Mederi Therapeutics, Inc.Inventors: David S. Utley, Scott West, John W. Gaiser, Rachel Croft
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Patent number: 9204926Abstract: A family of barrel structures is provided in a kit. Each barrel structure is differently sized and configured for advancement into anal canals of different anatomic morphologies. Instructions are provided for using the barrel structures to treat an individual. The instructions instruct assessing an anatomic morphology of an anal canal of an individual to be treated and selecting one of the barrel structures based upon the assessed anatomic morphology. Each barrel structure carries an electrode sized and configured to be coupled to a source of tissue ablation energy to be applied through the electrode to form a lesion. Each barrel structure includes a transparent side wall visualized by a direct line of sight from an end portion of the first barrel structure. The instructions instruct inserting the selected barrel structure into the anal canal and visualizing by the direct line of sight through the transparent side wall of the selected barrel structure the dentate line and the targeted tissue region.Type: GrantFiled: March 15, 2014Date of Patent: December 8, 2015Assignee: Mederi Therapeutics, Inc.Inventors: Scott H. West, John W. Gaiser, Patrick Rimroth, Larry C. Heaton
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Patent number: 9107674Abstract: Systems and methods for treating a tissue region employ an expandable structure projecting beyond the distal end of a catheter tube. A distal tail projects beyond the far end of the basket assembly. The distal tail includes a guidewire lumen that accommodates passage of a guidewire without threading the guidewire through the catheter tube.Type: GrantFiled: April 1, 2013Date of Patent: August 18, 2015Assignee: Mederi Therapeutics, Inc.Inventors: John W. Gaiser, Scott H. West, David S. Utley, David Huynh
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Publication number: 20150148701Abstract: Systems and methods deploy a therapeutic or diagnostic element into contact with a body tissue region. The systems and methods can sense position of the therapeutic or diagnostic element relative to a targeted tissue region without direct or indirect visualization, by sensing fluid pressure in a fluid path having an outlet located at or near the therapeutic or diagnostic element. The systems and methods can also inflate the therapeutic or diagnostic element during use, while taking steps to avoid over-inflation and/or while dynamically monitoring the pressure conditions within the expanded element.Type: ApplicationFiled: January 2, 2015Publication date: May 28, 2015Applicant: Mederi Therapeutics IncInventors: Robin Bek, John W. Gaiser, Scott West, Patrick Rimroth
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Publication number: 20150133917Abstract: A device for treating a tissue region at or near a lower esophageal sphincter to treat gastroesophageal reflux disease including a flexible tube having a plurality of arrays of first and second lumens, a proximal base, a distal hub, a plurality of radially spaced slits formed between the proximal base and distal hub, and a plurality of electrode ports and fluid ports, the electrode and fluid ports and the lumens are positioned between the slits. The tube is flexible outwardly between the slits to form an array of spines forming a three dimensional basket. A first electrode is movable within the first lumen of one array and a second electrode is movable within the first lumen of another array to exit through the electrode ports to penetrate tissue for application of energy to the tissue region to tighten the lower esophageal sphincter to treat gastroesophageal reflux disease.Type: ApplicationFiled: November 8, 2014Publication date: May 14, 2015Applicant: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley, Scott H. West, Jay Qin
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Publication number: 20150094710Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.Type: ApplicationFiled: November 30, 2014Publication date: April 2, 2015Applicant: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley, Scott H. West, Jay Qin, Peter H. Muller
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Publication number: 20150045789Abstract: An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.Type: ApplicationFiled: October 25, 2014Publication date: February 12, 2015Applicant: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley, Jay J. Qin
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Publication number: 20150045786Abstract: A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity. A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus.Type: ApplicationFiled: October 10, 2014Publication date: February 12, 2015Applicant: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley
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Publication number: 20150011990Abstract: A device for treating a tissue region is supplied with a separate usage key card. The usage key card comprises a storage medium, which is formatted to contain an identification code unique to the usage key card. The usage key card is adapted to be read by a remote reader, to download the identification code for processing by a controller for the device. Processing of the identification code by the controller either enables or disables operation of the device according to prescribed criteria. A viewable image is generated on a display screen that changes in response to processing of the identification code.Type: ApplicationFiled: September 21, 2014Publication date: January 8, 2015Applicant: Mederi Therapeutics, Inc.Inventors: Jay Qin, Robin Bek, John W. Gaiser, David S. Utley
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Patent number: 8906010Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.Type: GrantFiled: December 10, 2007Date of Patent: December 9, 2014Assignee: Mederi Therapeutics, Inc.Inventors: Stuart D Edwards, John W. Gaiser, David S Utley, Scott H. West, Jay Qin, Peter H Muller
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Patent number: 8894646Abstract: An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.Type: GrantFiled: August 30, 2013Date of Patent: November 25, 2014Assignee: Mederi Therapeutics, Inc.Inventors: Stuart D. Edwards, John W. Gaiser, David S. Utley, Jay J. Qin