Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Dynamic campaign optimization systems and methods may be used to continuously test many alternative campaign configurations while allowing all configurations, including configurations formerly identified as successful and unsuccessful, to be re-tested in order to identify successful configurations that may previously have been identified as unsuccessful.

Abstract: In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.

Abstract: The present application discloses an efficient process for the preparation of N-acetyl-L-cysteine amide (NACA) starting with N-acetyl-L-cysteine.

Abstract: The present application discloses an efficient process for the preparation of N-acetyl-L-cysteine amide (NACA) starting with N-acetyl-L-cysteine.

Abstract: The present application discloses an efficient process for the preparation of N-acetyl-L-cysteine amide (NACA) starting with N-acetyl-L-cysteine.

Abstract: The present application discloses an efficient process for the preparation of N-acetyl-L-cysteine amide (NACA) starting with N-acetyl-L-cysteine.

Abstract: In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.

Abstract: A method of treating particulate biodegradable organic waste by thermal hydrolysis. The method includes subjecting a quantity of the particulate biodegradable waste to thermal hydrolysis at a temperature above about 130° C. and a pressure at or above the saturated water vapor pressure to produce a slurry. The slurry will include solubilized organic material and unhydrolyzed residual solids. The method further includes decreasing the pressure at which the slurry is maintained. Typically, the step of decreasing slurry pressure will occur in a flash tank, which allows the separation of an organic acid-rich steam from other hydrolysis products. The method further includes capturing the steam or other condensable gases released when pressure is decreased and condensing the steam or other condensable gases into a condensate. The captured condensate may then be added to a quantity of particulate biodegradable waste prior to thermal hydrolysis. Also disclosed is an apparatus for practicing the method described above.

Abstract: A bone allograft and cortical pin for inserting into a surgically altered site of a human. The cortical pin is cylindrically shaped and has a thick middle diameter surrounded by two smaller end portions. The allograft has two end cortical wafers with small canals to receive the small ends of the cortical pin. At least one cancellous wafer is disposed adjacently between the end cortical bone wafers. A plurality of cancellous and/or cortical wafers may be inserted between the end cortical wafers to form the allograft. The wafers inserted between the end cortical wafers have larger canals to receive the thick diameter of the cortical pin. The size of the allograft may be adjusted as desired by either adding or removing inner wafers, or adjusting the size of the inner wafers of the allograft. The allograft and cortical pin are inserted parallel to the plane of insertion into the human.

Abstract: Various embodiments and methods are disclosed relating to one or more media guides configured to guide a surface being printed upon relative to a manually moved print device.

Abstract: Compounds of formula (I): and their use in the inhibition of Trk activity are described.

Abstract: Various embodiments and methods are disclosed relating to one or more media guides configured to guide a surface being printed upon relative to a manually moved print device.

Abstract: A method of treating particulate biodegradable organic waste by thermal hydrolysis. The method includes subjecting a quantity of the particulate biodegradable waste to thermal hydrolysis at a temperature above about 130° C. and a pressure at or above the saturated water vapor pressure to produce a slurry. The slurry will include solubilized organic material and unhydrolyzed residual solids. The method further includes decreasing the pressure at which the slurry is maintained. Typically, the step of decreasing slurry pressure will occur in a flash tank, which allows the separation of an organic acid-rich steam from other hydrolysis products. The method further includes capturing the steam or other condensable gases released when pressure is decreased and condensing the steam or other condensable gases into a condensate. The captured condensate may then be added to a quantity of particulate biodegradable waste prior to thermal hydrolysis. Also disclosed is an apparatus for practicing the method described above.

Abstract: A method of forming a lamp assembly includes removably coupling a burner assembly to a datum structure, the burner assembly including a fireball, moving the datum structure and the burner assembly to an aligned position relative to a reflector such that the fireball is at a focal point of the reflector, and securing the datum structure and the reflector in the aligned position.

Abstract: An apparatus for treating particulate biodegradable organic waste includes a thermal hydrolysis reactor receiving the particulate biodegradable organic waste for performing thermal hydrolysis at a temperature of about 130° C. at a pressure at or above the saturated water vapor pressure of the organic waste to produce a slurry including solubilized organic material and residual solids. A pH adjustment means for adjusting the pH of the particulate biodegradable organic waste as necessary to provide an acidic pH of greater than about 3.15 before thermo hydrolysis of the particulate biodegradable organic waste is provided. Separating means receive the solubilized organic material and residual solids for separating solubilized organic material from the residual solids. An anaerobic reactor is configured to receive the solubilized organic material.

Abstract: A method for treating particulate biodegradable organic waste includes sizing the waste and adding a base prior to introducing the waste to a thermal hydrolysis reactor and hydrolyzing the waste at a temperature of about 130° C. or greater and a pressure greater than the saturated water vapor pressure to produce a slurry including solubilized organic material and residual solids. The solubilized organic material is separated from the residual solids using a liquid/solid separator and the solubilized organics are subjected to anaerobic digestion to produce a methane gas. The base is preferably potassium hydroxide (KOH) at a concentration of about 1%. The method may further include preheating the particulate biodegradable organic waste with latent heat of the separated solubilized organic material prior to thermal hydrolysis.

Abstract: A method for treating particulate biodegradable organic waste includes sizing the waste and adding a base prior to introducing the waste to a thermal hydrolysis reactor and hydrolyzing the waste at a temperature of about 130° C. or greater and a pressure greater than the saturated water vapor pressure to produce a slurry including solubilized organic material and residual solids. The solubilized organic material is separated from the residual solids using a liquid/solid separator and the solubilized organics are subjected to anaerobic digestion to produce a methane gas. The base is preferably potassium hydroxide (KOH) at a concentration of about 1%. The method may further include preheating the particulate biodegradable organic waste with latent heat of the separated solubilized organic material prior to thermal hydrolysis.

Abstract: Squarylium compounds of the formula: wherein Q1 and Q2 are each independently a pyrylium, thiopyrylium, selenopyrylium, benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus, and R1 and R2 are each independently an aliphatic or cycloaliphatic group, can be prepared by reacting a squaric acid derivative of the formula: with a compound of the formula Q2CH2R2 in the presence of a base. The derivatives of Formula II may be prepared by condensing a 2,3,4,4-tetrahalocyclobut-2-en-1-one with a compound of the formula Q1CH2R1 in the presence of a base to produce a compound of the formula: wherein Q1 and R1 are as defined above, and X represents chlorine or bromine, and hydrolyzing the compound of Formula III.