Patents by Inventor John W. Lippert

John W. Lippert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combretastatin A-1 phosphate and combretastatin B-1 phosphate prodrugs
    Patent number: 7078552
    Abstract: The present invention relates to the syntheses and structural elucidation of Combretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrugs and the utilization of those prodrugs in the treatment of neoplastic diseases. The prodrugs described herein have the structure: Combretastin A-1 Phosphate Prodrug (I) and Combretastin B-1 Phosphate Prodrug (II).
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: July 18, 2006
    Assignee: Arizona Board of Regents
    Inventors: George R. Pettit, John W. Lippert, III
  • Antitubulin assembly and cell growth inhibitor denominated "dioxostatin"
    Publication number: 20040122083
    Abstract: A new inhibitor of microtubule assembly (IC50 0.59 &mgr;M); with antineoplastic properties, denominated “dioxostatin”, has been synthesized and its effectiveness against human cancer and murine P388 lymphocytic leukemia cell lines demonstrated. Dioxostatin hs the following structure (I).
    Type: Application
    Filed: March 31, 2003
    Publication date: June 24, 2004
    Inventors: George R Pettit, John W Lippert
  • Combrestatin a-1 phosphate and combrestatin b-1 phosphate prodrugs
    Publication number: 20030220298
    Abstract: The present invention relates to the syntheses and structural elucidation of Combretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrugs and the utilization of those prodrugs in the treatment of neoplastic diseases. The prodrugs described herein have the structure: Combretastin A-1 Phosphate Prodrug (I) and Combretastin B-1 Phosphate Prodrug (II).
    Type: Application
    Filed: October 25, 2002
    Publication date: November 27, 2003
    Inventors: George R. Pettit, John W. Lippert