Patents by Inventor John W. Ludlow

John W. Ludlow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOACTIVE RENAL CELLS
    Publication number: 20240409941
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: June 21, 2024
    Publication date: December 12, 2024
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 12157887
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: December 3, 2024
    Assignee: ProKidney
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric S. Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Jr., Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • RENAL CELL POPULATIONS AND USES THEREOF
    Publication number: 20220347221
    Abstract: The present invention concerns enriched heterogeneous mammalian renal cell populations characterized by biomarkers, and methods of making and using the same.
    Type: Application
    Filed: May 26, 2022
    Publication date: November 3, 2022
    Inventors: Joydeep Basu, Kelly Guthrie, Dominic Justewicz, Teresa Burnette, Andrew Bruce, Russell W. Kelley, John W. Ludlow
  • Renal cell populations and uses thereof
    Patent number: 11369639
    Abstract: The present invention concerns enriched heterogeneous mammalian renal cell populations characterized by biomarkers, and methods of making and using the same.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: June 28, 2022
    Assignee: ProKidney
    Inventors: Joydeep Basu, Kelly Guthrie, Dominic Justewicz, Teresa Burnette, Andrew Bruce, Russell W. Kelley, John W. Ludlow
  • BIOACTIVE RENAL CELLS
    Publication number: 20210238600
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: February 9, 2021
    Publication date: August 5, 2021
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric S. Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Jr., Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 11066666
    Abstract: The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: July 20, 2021
    Assignee: inRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • RENAL CELL POPULATIONS AND USES THEREOF
    Publication number: 20200101112
    Abstract: The present invention concerns enriched heterogeneous mammalian renal cell populations characterized by biomarkers, and methods of making and using the same.
    Type: Application
    Filed: July 1, 2019
    Publication date: April 2, 2020
    Inventors: Joydeep Basu, Kelly Guthrie, Dominic Justewicz, Teresa Burnette, Andrew Bruce, Russell W. Kelley, John W. Ludlow
  • Renal cell populations and uses thereof
    Patent number: 10363274
    Abstract: The present invention concerns enriched heterogeneous mammalian renal cell populations characterized by biomarkers, and methods of making and using the same.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: July 30, 2019
    Assignee: INREGEN
    Inventors: Joydeep Basu, Kelly Guthrie, Dominic Justewicz, Teresa Burnette, Andrew Bruce, Russell W. Kelley, John W. Ludlow
  • BIOACTIVE RENAL CELLS
    Publication number: 20180282726
    Abstract: The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: March 19, 2018
    Publication date: October 4, 2018
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darrell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 10077442
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: September 18, 2018
    Assignee: inRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 10030242
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: July 24, 2018
    Assignee: InRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • EXOSOME COMPOSITIONS AND USE THEREOF FOR SOFT TISSUE REPAIR
    Publication number: 20180177828
    Abstract: Stem cell exosome-containing compositions are provided, along with methods for their preparation and use for repair of soft tissue damage including treatment of skin conditions and periodontitis. The compositions provided contain isolated stem cell exosomes having increased levels of heat shock stress-response molecules. Uses of the exosome-containing compositions include treating a wound, a burn, a burn resulting from radiation treatment, a discoloration, a scar, and a keloid.
    Type: Application
    Filed: January 31, 2018
    Publication date: June 28, 2018
    Inventors: John W. Ludlow, Benjamin Buehrer, Peter Pieraccini
  • EXOSOME COMPOSITIONS AND METHODS FOR PREPARATION AND USE THEREOF FOR REGULATING AND CONDITIONING SKIN AND HAIR
    Publication number: 20180147420
    Abstract: Improved stem cell exosome-containing compositions are provided, along with methods for their preparation and use for regulating skin condition. The compositions provided contain isolated stem cell exosomes having increased levels of heat shock stress-response molecules. Uses of the exosome-containing compositions for regulating human skin include inducing increased skin integrity by cell renewal, enhancing water content or moisture of skin, reducing trans epidermal water loss, skin flaking, and scaling, improving skin thickness, enhancing skin tensile properties, reducing the appearance of dermal fine lines and wrinkles, improving skin texture, reducing skin pores size, enhancing skin smoothness, improving skin age spots, improving skin tone, and improving the appearance of scars and skin abrasions.
    Type: Application
    Filed: January 31, 2018
    Publication date: May 31, 2018
    Inventors: John W. Ludlow, Benjamin Buehrer, Peter Pieraccini
  • CELL SCAFFOLD CONSTRUCTS
    Publication number: 20180071074
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Application
    Filed: May 18, 2017
    Publication date: March 15, 2018
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • RENAL CELL POPULATIONS AND USES THEREOF
    Publication number: 20170281684
    Abstract: The present invention concerns enriched heterogeneous mammalian renal cell populations characterized by biomarkers, and methods of making and using the same.
    Type: Application
    Filed: June 14, 2017
    Publication date: October 5, 2017
    Inventors: Joydeep Basu, Kelly Guthrie, Dominic Justewicz, Teresa Burnette, Andrew Bruce, Russell W. Kelley, John W. Ludlow
  • PRIMITIVE AND PROXIMAL HEPATIC STEM CELLS
    Publication number: 20170096641
    Abstract: Hepatic progenitors comprise two populations of human hepatic stem cells, primitive and proximal hepatic stem cells, and two populations of committed progenitors, one for biliary cells and one for hepatocytes. Human primitive hepatic stem cells are a very small fraction of the liver cell population and give rise to proximal hepatic stem cells constituting a much larger fraction of the liver. Human proximal hepatic stem cells give rise to biliary and hepatocyte committed progenitors. Primitive and proximal stem cells are the primary stem cells for the human liver. Human primitive hepatic stem cells may be isolated by immunoselection from human livers or culturing human liver cells under conditions which select for a human primitive hepatic stem cell. Proximal hepatic stem cells may be isolated by immunoselection, or by culturing human liver cells under conditions which include a developmental factor.
    Type: Application
    Filed: October 12, 2016
    Publication date: April 6, 2017
    Applicants: Vesta Therapeutics Inc., University of North Carolina at Chapel Hill
    Inventors: Lola M. REID, Nicholas MOSS, Mark E. FURTH, John W. LUDLOW, Andrew T. BRUCE
  • ADIPOSE DERIVED ADULT STEM CELLS IN HEPATIC REGENERATION
    Publication number: 20160237408
    Abstract: The present invention provides a method to derive hepatic stem cells from stem cells derived from non-liver tissue. In one embodiment of the invention, hepatic stem cells are derived from adipose stem cells. The invention also provides a method of enhancing hepatic cytokine production (e.g., HGF) from ASCs, which may be useful in the regeneration of liver tissue when transplanted in vivo. Tissue culture conditions, including media conditions, are provided.
    Type: Application
    Filed: February 1, 2016
    Publication date: August 18, 2016
    Applicants: Louisiana State University, Artecel, Inc.
    Inventors: Jeffery M. GIMBLE, John W. LUDLOW
  • Cell scaffold constructs
    Patent number: 9271824
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: March 1, 2016
    Assignee: REGENMEDTX, LLC
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • Adipose derived adult stem cells in hepatic regeneration
    Patent number: 9249393
    Abstract: The present invention provides a method to derive hepatic stem cells from stem cells derived from non-liver tissue. In one embodiment of the invention, hepatic stem cells are derived from adipose stem cells. The invention also provides a method of enhancing hepatic cytokine production (e.g., HGF) from ASCs, which may be useful in the regeneration of liver tissue when transplanted in vivo. Tissue culture conditions, including media conditions, are provided.
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: February 2, 2016
    Assignees: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE, ARTECEL, INC
    Inventors: Jeffery M. Gimble, John W. Ludlow
  • RENAL CELL POPULATIONS AND USES THEREOF
    Publication number: 20150246073
    Abstract: The present invention concerns enriched heterogeneous mammalian renal cell populations characterized by biomarkers, and methods of making and using the same.
    Type: Application
    Filed: October 24, 2013
    Publication date: September 3, 2015
    Inventors: Joydeep Basu, Kelly Guthrie, Dominic Justewicz, Teresa Burnette, Andrew Bruce, Russell W. Kelley, John W. Ludlow