Patents by Inventor JOHN W. LUECKE

JOHN W. LUECKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for subtyping diffuse large B-cell lymphoma (DLBCL)
    Patent number: 11384399
    Abstract: Described herein are innovations for classifying subtypes of DLBCL, as well as using the results of classification for diagnosis, prognosis, and therapy selection. In this way, the classifier can effectively classify subtypes of DLBCL and provide meaningful output for the benefit of medical practices and DLBCL patients. Also described are arrays and kits that can be used to measure expression of DLBCL signatures genes.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: July 12, 2022
    Assignee: HTG Molecular Diagnostics, Inc.
    Inventors: Bonnie LaFleur, Qian Liu, John W. Luecke, Patrick C. Roche
  • METHODS FOR SUBTYPING DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL)
    Publication number: 20180340231
    Abstract: Described herein are innovations for classifying subtypes of DLBCL, as well as using the results of classification for diagnosis, prognosis, and therapy selection. In this way, the classifier can effectively classify subtypes of DLBCL and provide meaningful output for the benefit of medical practices and DLBCL patients. Also described are arrays and kits that can be used to measure expression of DLBCL signatures genes.
    Type: Application
    Filed: September 29, 2016
    Publication date: November 29, 2018
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Bonnie LaFleur, Qian Liu, John W. Luecke, Patrick C. Roche
  • COMPOSITIONS AND METHODS FOR ALK MOLECULAR TESTING
    Publication number: 20130288915
    Abstract: Disclosed herein are methods of predicting response of a tumor to an ALK inhibitor and methods of determining diagnosis or prognosis of a subject with a tumor. The methods can include detecting presence of an ALK gene fusion (such as EML4-ALK, TFG-ALK, or KIF5B-ALK) in a sample from a subject. Also disclosed herein are arrays for detecting the presence of ALK and/or ROS1 gene fusions in a sample. In some embodiments, the array includes one or more oligonucleotides complementary to an ALK or ROS1 gene fusion.
    Type: Application
    Filed: April 3, 2013
    Publication date: October 31, 2013
    Applicant: HTG MOLECULAR DIAGNOSTICS, INC.
    Inventors: BRUCE E. SELIGMANN, BJ KERNS, MARK SCHWARTZ, JOHN W. LUECKE