Patents by Inventor John W. Martens

John W. Martens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Markers for the prediction of outcome of anthracycline treatment
    Patent number: 10053735
    Abstract: The present invention relates to methods for predicting the outcome of anthracycline treatment of cell proliferative disorder patients. This is achieved by determining the expression level of at least one gene selected from the group consisting of PITX2; TFF1 and PLAU. The invention also relates to sequences, oligonucleotides and antibodies which can be used within the described methods.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: August 21, 2018
    Assignee: THERAWIS DIAGNOSTICS GMBH
    Inventors: John Foekens, John W. Martens, Serenella Eppenberger-Castori, Vincent Vuaroqueaux, Frederique Spyratos, Nadia Harbeck, Manfred Schmitt, Heinz Hoefler, Sabine Maier, Gunter Weiss, Ralf Lesche, Thomas Hildmann, Achim Plum
  • Methods for the prognosis of breast cancer
    Patent number: 9017944
    Abstract: The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: April 28, 2015
    Assignee: Epigenomics AG
    Inventors: John Foekens, Nadia Harbeck, Thomas Koenig, Sabine Maier, John W. Martens, Fabian Model, Inko Nimmrich, Manfred Schmitt, Ralf Lesche, Dimo Dietrich, Volkmar Mueller, Antje Kluth Lukas, Ina Schwope, Oliver Hartmann, Peter Adorjan, Almuth Marx, Heinz Hoefler
  • Method for determining risk of relapse of breast cancer following tamoxifen adjuvant therapy
    Patent number: 8101359
    Abstract: The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: January 24, 2012
    Assignee: Epigenomics AG
    Inventors: John Foekens, Nadia Harbeck, Thomas Koenig, Sabine Maier, John W. Martens, Fabian Model, Inko Nimmrich, Tamas Rujan, Armin Schmitt, Manfred Schmitt, Maxime P. Look, Almuth Marx, Heinz Hoefler
  • EPIGENETIC METHODS AND NUCLEIC ACIDS FOR THE DETECTION OF BREAST CELL PROLIFERATIVE DISORDERS
    Publication number: 20110269126
    Abstract: The present application provides methods and nucleic acids for the detection and differentiation of breast cell proliferative disorders. This is achieved by the analysis of the methylation of a panel of genes, or subsets thereof. The invention may be used for the detection and/or differentiation of a variety of tissue types including breast cancer and benign breast disorders as well as other cancers and tissue types.
    Type: Application
    Filed: February 10, 2011
    Publication date: November 3, 2011
    Inventors: Ralf Lesche, Anne Fassbender, Klaus Juenemann, John Foekens, John W. Martens
  • Epigenetic methods and nucleic acids for the detection of breast cell proliferative disorders
    Publication number: 20090298054
    Abstract: The present application provides methods and nucleic acids for the detection and differentiation of breast cell proliferative disorders. This is achieved by the analysis of the methylation of a panel of genes, or subsets thereof. The invention may be used for the detection and/or differentiation of a variety of tissue types including breast cancer and benign breast disorders as well as other cancers and tissue types.
    Type: Application
    Filed: July 18, 2005
    Publication date: December 3, 2009
    Applicant: Epigenomics AG
    Inventors: Ralf Lesche, Anne Fassbender, Klaus Juenemann, John Foekens, John W. Martens