Patents by Inventor John W. McDonald

John W. McDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7991477
    Abstract: Methods for the treatment of CNS damage are described, and include inducing in a subject in need of such treatment, a therapeutically effective amount of functional electronic stimulation (FES) sufficient to evoke patterned movement in the subject's muscles, the control of which has been affected by the CNS damage. The induction of FES-evoked patterned movement at least partially restores lost motor and sensory function, and stimulates regeneration of neural progenitor cells in the subject patient.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: August 2, 2011
    Assignee: Washington University
    Inventor: John W. McDonald, III
  • Publication number: 20100114239
    Abstract: Methods for the treatment of CNS damage are described, and include inducing in a subject in need of such treatment, a therapeutically effective amount of functional electronic stimulation (FES) sufficient to evoke patterned movement in the subject's muscles, the control of which has been affected by the CNS damage. The induction of FES-evoked patterned movement at least partially restores lost motor and sensory function, and stimulates regeneration of neural progenitor cells in the subject patient.
    Type: Application
    Filed: September 11, 2009
    Publication date: May 6, 2010
    Applicant: WASHINGTON UNIVERSITY
    Inventor: John W. McDonald, III
  • Patent number: 7610096
    Abstract: Methods for the treatment of CNS damage are described, and include inducing in a subject in need of such treatment, a therapeutically effective amount of functional electronic stimulation (FES) sufficient to evoke patterned movement in the subject's muscles, the control of which has been affected by the CNS damage. The induction of FES-evoked patterned movement at least partially restores lost motor and sensory function, and stimulates regeneration of neural progenitor cells in the subject patient.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: October 27, 2009
    Assignee: Washington University
    Inventor: John W. McDonald, III
  • Patent number: 7305064
    Abstract: A method of assisting recovery of an injury site of brain or spinal cord injury includes providing a therapeutic dose of X-ray radiation to the injury site through an array of parallel microplanar beams. The dose at least temporarily removes regeneration inhibitors from the irradiated regions. Substantially unirradiated cells surviving between the microplanar beams migrate to the in-beam irradiated portion and assist in recovery. The dose may be administered in dose fractions over several sessions, separated in time, using angle-variable intersecting microbeam arrays (AVIMA). Additional doses may be administered by varying the orientation of the microplanar beams. The method may be enhanced by injecting stem cells into the injury site.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: December 4, 2007
    Assignee: Brookhaven Science Associates, LLC
    Inventors: F. Avraham Dilmanian, John W. McDonald, III
  • Patent number: 7158607
    Abstract: A method of assisting recovery of an injury site of brain or spinal cord injury includes providing a therapeutic dose of X-ray radiation to the injury site through an array of parallel microplanar beams. The dose at least temporarily removes regeneration inhibitors from the irradiated regions. Substantially unirradiated cells surviving between the microplanar beams migrate to the in-beam irradiated portion and assist in recovery. The dose may be administered in dose fractions over several sessions, separated in time, using angle-variable intersecting microbeam arrays (AVIMA). Additional doses may be administered by varying the orientation of the microplanar beams. The method may be enhanced by injecting stem cells into the injury site.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: January 2, 2007
    Assignee: Brookhaven Science Associates, LLC
    Inventors: F. Avraham Dilmanian, John W. McDonald, III
  • Publication number: 20040127954
    Abstract: Methods for the treatment of CNS damage are described, and include inducing in a subject in need of such treatment, a therapeutically effective amount of functional electronic stimulation (FES) sufficient to evoke patterned movement in the subject's muscles, the control of which has been affected by the CNS damage. The induction of FES-evoked patterned movement at least partially restores lost motor and sensory function, and stimulates regeneration of neural progenitor cells in the subject patient.
    Type: Application
    Filed: September 4, 2003
    Publication date: July 1, 2004
    Applicant: The Washington University
    Inventor: John W. McDonald
  • Patent number: 6631752
    Abstract: This invention discloses a method of improving the die casting process by the application of the inventor's mathematics and physics stored in a computer to control the injection speed and the timing of the excitation of an intensifier. Using either data from a die surface temperature for a selected location detected by a pyrometer, the last instant before the die is closed, or the alloy-die interface boundary data from a thermocouple, the inventor's equations loaded in a computer calculate and graph the solidification pattern for the casting wall and the quantity of heat remaining in the alloy wall vs. time above the dynamic solidus thereby establishing parameters for control of facets of the injection phase. The unique properties of the boundary's transient temperature during solidification have been shown by the inventor's mathematics to be of vital import to the determination of the solidification pattern used to control injection.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: October 14, 2003
    Assignee: DieCast Software Inc.
    Inventor: John W. McDonald
  • Publication number: 20020170699
    Abstract: This invention discloses a method of improving the die casting process by the application of the inventor's mathematics and physics stored in a computer to control the injection speed and the timing of the excitation of an intensifier. Using either data from a die surface temperature for a selected location detected by a pyrometer, the last instant before the die is closed, or the alloy-die interface boundary data from a thermocouple, the inventor's equations loaded in a computer calculate and graph the solidification pattern for the casting wall and the quantity of heat remaining in the alloy wall vs. time above the dynamic solidus thereby establishing parameters for control of facets of the injection phase. The unique properties of the boundary's transient temperature during solidification have been shown by the inventor's mathematics to be of vital import to the determination of the solidification pattern used to control injection.
    Type: Application
    Filed: May 30, 2002
    Publication date: November 21, 2002
    Inventor: John W. McDonald
  • Patent number: 6197010
    Abstract: A low-profile faceplate assembly for a two-piece ostomy appliance, and a method for manufacturing it, are disclosed. The faceplate includes a wafer of an adhesive skin barrier material and a flexible plastic coupling ring (for detachably coupling the faceplate to an ostomy pouch having a mating ring), and is distinguished by the mounting flange of the coupling ring being embedded within the faceplate.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: March 6, 2001
    Assignee: Hollister Incorporated
    Inventors: Walter F. Leise, Jr., Ronald S. Botten, John W. McDonald, Jr., Demetrios Rigas, James J. Passalaqua
  • Patent number: 6106507
    Abstract: A faceplate for an ostomy appliance is disclosed in which a unitary release sheet covers both the bodyside (rear) surface of an adhesive skin barrier layer and the surrounding adhesive surface of an outwardly-projecting porous covering layer. The barrier layer is beveled to a feathered outer edge and the release sheet contacts the adhesive surface of the covering layer immediately adjacent the outer edge of said barrier layer. A continuous in-line method for making such faceplates is disclosed.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: August 22, 2000
    Assignee: Hollister Incorporated
    Inventors: Ronald S. Botten, Walter F. Leise, Jr., John W. McDonald, Jr.
  • Patent number: 6093276
    Abstract: A low-profile faceplate assembly for a two-piece ostomy appliance, and a method for manufacturing it, are disclosed. The faceplate includes a wafer of an adhesive skin barrier material and a flexible plastic coupling ring (for detachably coupling the faceplate to an ostomy pouch having a mating ring), and is distinguished by the mounting flange of the coupling ring being embedded within the faceplate. The faceplate is made by a convergence of in-line processes taking place simultaneously with an injection/compression molding operation for the skin barrier wafer as disclosed in U.S. Pat. No. 5,716,475, thereby eliminating or greatly reducing the assembly labor for the various process steps plus the handling, storing and transferring steps commonly associated with the manufacture of ostomy faceplate assemblies.
    Type: Grant
    Filed: June 11, 1998
    Date of Patent: July 25, 2000
    Assignee: Hollister Incorporated
    Inventors: Walter F. Leise, Jr., Ronald S. Botten, John W. McDonald, Jr., Demetrios Rigas, James J. Passalaqua
  • Patent number: 4206799
    Abstract: A die member in an ejector die assembly is movable obliquely with respect to the axis of movement of the ejector die assembly. Backup plate means is connected to the ejector die assembly by a lost motion connection. The backup plate means locks the die member by direct engagement with the die member in the machine closed position and is moved away from the ejector die assembly in the machine open position to permit withdrawal of the die member from the die cavity.
    Type: Grant
    Filed: December 11, 1978
    Date of Patent: June 10, 1980
    Inventor: John W. McDonald
  • Patent number: 4156671
    Abstract: Production of a solution of a chloroprene polymer, suitable for use as a component for an adhesive, by dissolving the polymer in a solvent, and heating the solution, adding a free-radical catalyst and contacting the solution with a molecular oxygen containing gas, until the viscosity of the solution is lowered by at least about 10%.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: May 29, 1979
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Robert W. Keown, John W. McDonald, Jurgen K. Weise
  • Patent number: D243229
    Type: Grant
    Filed: September 25, 1975
    Date of Patent: February 1, 1977
    Assignee: Ethyl Development Corporation
    Inventor: John W. McDonald
  • Patent number: D270137
    Type: Grant
    Filed: March 19, 1981
    Date of Patent: August 16, 1983
    Assignee: Realex Corporation
    Inventors: John W. McDonald, John M. B. Ford
  • Patent number: D271748
    Type: Grant
    Filed: February 16, 1983
    Date of Patent: December 13, 1983
    Assignee: Realex Corporation
    Inventors: John W. McDonald, John M. B. Ford
  • Patent number: D272236
    Type: Grant
    Filed: June 22, 1981
    Date of Patent: January 17, 1984
    Assignee: Realex Corporation
    Inventor: John W. McDonald