Patents by Inventor John W. Mirc

John W. Mirc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soluble guanylate cyclase activators
    Patent number: 8895583
    Abstract: This inventions relates to compounds having the structure Formula I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: November 25, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: John Q. Tan, Ronald M. Kim, John W. Mirc
  • SOLUBLE GUANYLATE CYCLASE ACTIVATORS
    Publication number: 20130210798
    Abstract: This inventions relates to compounds having the structure Formula I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
    Type: Application
    Filed: October 24, 2011
    Publication date: August 15, 2013
    Inventors: John Q. Tan, Ronald M. Kim, John W. Mirc
  • Soluble guanylate cyclase activators
    Patent number: 8455638
    Abstract: A compound having the structure useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, angina pectoris, thromboses, restenoses, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver in a human or animal patient.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: June 4, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Amy R. Bittner, Ronald M. Kim, John W. Mirc, Emma R. Parmee, Christopher Joseph Sinz, Qiang Tan