Abstract: Tissue treatment systems and methods are disclosed. A tissue treatment system comprises a signal generator, a sensing circuit coupleable to electrode(s) of a catheter, and a controller. The sensing circuit senses neural activity of nerves within tissue surrounding a biological lumen using electrode(s) of the catheter inserted into the biological lumen. The controller determines one or more characteristics of the sensed neural activity of the nerves within the tissue surrounding the biological lumen. The controller also selects one or more denervation parameters based on the one or more characteristics of the sensed neural activity, and controls the signal generator to generate, using the selected one or more denervation parameters, signals for performing a denervation procedure intended to denervate at least some of the nerves for which the neural activity was sensed.

Abstract: Card locks for securing electronics card in card slots within cages and designed and configured to allow each card lock to impart high uniform pressure between an electronics card and the corresponding card slot to maximize heat transfer from the electronics card to the card cage to efficiently sink heat generated onboard the electronics card. In some embodiments, a high-pressure card lock of the present disclosure has a pair of low-angle wedges and a locking mechanism that effectively pushes one of the wedges along the other wedge to put the high-pressure card lock into its locked, high-pressure-exerting state. In other embodiments, a high-pressure card lock of the present disclosure has a pair of low-angle wedges and a locking mechanism that effectively draws one of the wedges along the other wedge to put the high-pressure card lock into its locked, high-pressure-exerting state.

Abstract: Card locks for securing electronics card in card slots within cages and designed and configured to allow each card lock to impart high uniform pressure between an electronics card and the corresponding card slot to maximize heat transfer from the electronics card to the card cage to efficiently sink heat generated onboard the electronics card. In some embodiments, a high-pressure card lock of the present disclosure has a pair of low-angle wedges and a locking mechanism that effectively pushes one of the wedges along the other wedge to put the high-pressure card lock into its locked, high-pressure-exerting state. In other embodiments, a high-pressure card lock of the present disclosure has a pair of low-angle wedges and a locking mechanism that effectively draws one of the wedges along the other wedge to put the high-pressure card lock into its locked, high-pressure-exerting state.