Patents by Inventor John W. Safford, Jr.

John W. Safford, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hapten-inhibitor immunoassay
    Patent number: 4430263
    Abstract: A specific binding assay method employing, as a labeling substance, a reversible trypsin inhibitor for the detection of a hapten. Competition between the hapten to be determined and hapten trysin inhibitor conjugate for antibody to the hapten, in the presence of enzyme, followed by addition of enzyme substrate provides an effective method for hapten analysis. The preferred trypsin inhibitor is a protein having a molecular weight range of 2,000-75,000. The preferred ratio of the hapten to the inhibitor in the conjugate is between 1:1 and 3:1.
    Type: Grant
    Filed: January 21, 1980
    Date of Patent: February 7, 1984
    Assignee: Abbott Laboratories
    Inventors: Steven C. March, John W. Safford, Jr., Susan E. Magic
  • Process for producing a soluble rubella antigen
    Patent number: 4195074
    Abstract: Purified soluble antigen, specific for rubella virus, is isolated from growth media of rubella-infected cell cultures by affinity and gel permeation chromatography and characterized, inter alia, by its specific activity. Antigen-sensitized particles are employed as immunoassay reagents in, for example, agglutination assays for detection and quantification of rubella antibodies in body fluids such as serum, spinal fluid and the like.
    Type: Grant
    Filed: January 31, 1978
    Date of Patent: March 25, 1980
    Assignee: Abbott Laboratories
    Inventor: John W. Safford, Jr.