Patents by Inventor John W. Tomsho

John W. Tomsho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protective groups and methods for protecting benzoxaboroles or oxaboroles
    Patent number: 11773114
    Abstract: The present invention relates in part protective groups that can be used to reversibly protect benzoxaboroles and yield the corresponding protected complexes. The invention further relates to the use of these protective groups to protect benzoxaboroles.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: October 3, 2023
    Assignee: Saint Joseph's University
    Inventors: John W. Tomsho, James M. Gamrat
  • PROTECTIVE GROUPS AND METHODS FOR PROTECTING BENZOXABOROLES OR OXABOROLES
    Publication number: 20220298179
    Abstract: The present invention relates in part protective groups that can be used to reversibly protect benzoxaboroles and yield the corresponding protected complexes. The invention further relates to the use of these protective groups to protect benzoxaboroles.
    Type: Application
    Filed: June 6, 2022
    Publication date: September 22, 2022
    Inventors: John W. Tomsho, James M. Gamrat
  • Protective groups and methods for protecting benzoxaboroles or oxaboroles
    Patent number: 11427603
    Abstract: The present invention relates in part to protective groups that can be used to reversibly protect benzoxaboroles and/or oxaboroles and yield the corresponding protected complexes. The invention further relates to the use of these protective groups to protect benzoxaboroles and/or oxaboroles.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: August 30, 2022
    Assignee: University of the Sciences
    Inventors: John W. Tomsho, James M. Gamrat
  • PROTECTIVE GROUPS AND METHODS FOR PROTECTING BENZOXABOROLES OR OXABOROLES
    Publication number: 20200407375
    Abstract: The present invention relates in part to protective groups that can be used to reversibly protect benzoxaboroles and/or oxaboroles and yield the corresponding protected complexes. The invention further relates to the use of these protective groups to protect benzoxaboroles and/or oxaboroles.
    Type: Application
    Filed: March 11, 2019
    Publication date: December 31, 2020
    Applicant: University of the Sciences
    Inventors: John W. Tomsho, James M. Gamrat
  • Boronic and borinic acid compound as inhibitors of sulfenic acid-containing proteins
    Patent number: 9309508
    Abstract: A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: April 12, 2016
    Assignee: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Stephen Benkovic, Chunyu Liu, John W. Tomsho
  • Boronic and Borinic Acid Compound as Inhibitors of Sulfenic Acid-Containing Proteins
    Publication number: 20150140635
    Abstract: A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
    Type: Application
    Filed: December 19, 2014
    Publication date: May 21, 2015
    Inventors: Stephen Benkovic, Chunyu Liu, John W. Tomsho
  • Boronic and borinic acid compounds as inhibitors of sulfenic acid-containing proteins
    Patent number: 8980544
    Abstract: A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: March 17, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Stephen Benkovic, Chunyu Liu, John W. Tomsho
  • Boronic and Borinic Acid Compounds as Inhibitors of Sulfenic Acid-Containing Proteins
    Publication number: 20140147905
    Abstract: A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
    Type: Application
    Filed: August 27, 2013
    Publication date: May 29, 2014
    Inventors: Stephen Benkovic, Chunyu Liu, John W. Tomsho