Patents by Inventor John W. Wallen, III

John W. Wallen, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION OF IMMUNOMODULATING SERPIN, SERP-1
    Publication number: 20230173080
    Abstract: Disclosed herein, in some embodiments, are modified Serp-1 proteins. The modified Serp-1 protein may include a therapeutic enhancing moiety, and be biologically active. In some cases, the therapeutic enhancing moiety is a water soluble polymer such as polyethylene glycol.
    Type: Application
    Filed: April 26, 2021
    Publication date: June 8, 2023
    Inventors: Alexandra LUCAS, Liqiang ZHANG, Jordan R. YARON, Qiuyun GUO, John W. WALLEN, III
  • MODIFIED IFNL3 POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING MOIETY AND THEIR USES
    Publication number: 20220275041
    Abstract: Non-human IFNL3 polypeptides and their uses thereof are provided. Exemplary embodiments provide IFNL3 polypeptides which include one or more amino acid substitutions, additions, or deletions with natural or non-naturally encoded amino acids, and/or linkage or fusion to other biologically active molecules including other IFNL3 polypeptides, as well as PK enhancing moieties (PKEMs). Additionally, use of said IFNL3 polypeptides for innate immune system stimulation, as a vaccine adjuvant, as well as treatment or prevention of diseases such as viral and bacterial infections, and inflammation, is also provided.
    Type: Application
    Filed: August 22, 2019
    Publication date: September 1, 2022
    Inventors: John W. WALLEN, III, Matthew CALDEMEYER
  • MODIFIED PORCINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES
    Publication number: 20120283172
    Abstract: Modified porcine somatotropin polypeptides and uses thereof are provided.
    Type: Application
    Filed: December 21, 2010
    Publication date: November 8, 2012
    Applicant: AMBRX, INC.
    Inventors: John W. Wallen, III, Nick Knudsen, Vadim Kraynov
  • Non-Natural Amino Acid Polypeptides Having Modified Immunogenicity
    Publication number: 20090093405
    Abstract: Non-naturally encoded amino acid polypeptides with modulated immunogenicity and uses thereof are provided.
    Type: Application
    Filed: January 18, 2007
    Publication date: April 9, 2009
    Applicant: AMBRX, INC.
    Inventors: John W. Wallen, III, Bee-Cheng Sim, Bruce Kimmel, Thomas O. Daniel