Patents by Inventor John Wall Rayner

John Wall Rayner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzofuran derivatives, process for their preparation and intermediates thereof
    Patent number: 7709505
    Abstract: Compound of formula (I) wherein A is selected from pyridin-2-yl or thiazol-2-yl and R1, R2 and R3 are as described in the specification and their use in the treatment or prevention of a disease or medical conditions mediated through glucokinase.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: May 4, 2010
    Assignee: AstraZeneca AB
    Inventors: Darren McKerrecher, John Wall Rayner
  • Heterocyclic derivatives
    Patent number: 6936610
    Abstract: The invention relates to heterocyclic derivatives of formula (I) A—B—X1—T1(R2)—L1—T2(R3)—X2—Q??(I) or pharmaceutically-acceptable salts thereof, which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: August 30, 2005
    Assignee: AstraZeneca UK Limited
    Inventors: Andrew Stocker, John Preston, John Wall Rayner, Michael James Smithers, Paul Turner
  • Heterocyclic derivatives
    Publication number: 20030195203
    Abstract: The invention relates to heterocyclic derivatives of formula (I)
    Type: Application
    Filed: September 27, 2001
    Publication date: October 16, 2003
    Inventors: Andrew Stocker, John Preston, John Wall Rayner, Michael James Smithers, Paul Turner
  • Heterocycle derivatives which inhibit factor Xa
    Patent number: 6300330
    Abstract: The invention relates to heterocyclic derivatives of the formula (I): A—B—X1—T1(R2)—L1—T2(R3)—X2—Q or pharmaceutically acceptable salts thereof, which possess antithrombotic and anticoagulant properties due to their inhibition of Factor Xa and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: October 9, 2001
    Assignee: Zeneca Limited
    Inventors: Andrew Stocker, John Preston, John Wall Rayner, Michael James Smithers, Paul Turner
  • Heterocyclic derivatives
    Patent number: 5728701
    Abstract: Compounds of formula I ##STR1## and metabolically labile esters and amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.13, M.sup.2, X.sup.1, Z.sup.1, Z.sup.1a, X.sup.2 and A.sup.1 have the meanings given in the specification. The compounds are useful as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa. Novel intermediates are also disclosed.
    Type: Grant
    Filed: March 18, 1997
    Date of Patent: March 17, 1998
    Assignee: Zeneca Limited
    Inventors: Michael Garth Wayne, Michael James Smithers, John Wall Rayner, Alan Wellington Faull, Robert James Pearce, Andrew George Brewster, Richard Eden Shute, Stuart Dennett Mills, Peter William Rodney Caulkett
  • Heterocyclic derivatives
    Patent number: 5652242
    Abstract: Compounds of formula I ##STR1## and metabolically labile esters and amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.13, M.sup.2, X.sup.1, Z.sup.1, Z.sup.1a, X.sup.2 and A.sup.1 have the meanings given in the specification. The compounds are useful as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa. Novel intermediates are also disclosed.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: July 29, 1997
    Assignee: Zeneca Limited
    Inventors: Michael Garth Wayne, Michael James Smithers, John Wall Rayner, Alan Wellington Faull, Robert James Pearce, Andrew George Brewster, Richard Eden Shute, Stuart Dennett Mills, Peter William Rodney Caulkett