Abstract: An implantable medical device for the release of bioactive agents at desired rates is described. The device includes a body member with two or more aperture sets and an inner space. The bioactive agents are arranged within the inner space of the body member so that each bioactive agent present in the inner space is individually releasable through their respective aperture set. The aperture sets modulate the release of the bioactive agents from the body member. Arrangement of apertures and bioactive agents within the inner portion chosen to provide desired and independent release rates from the device.

Abstract: Arrays including microparticles having probe and marker moieties are used for the detection of a target in a sample. Microparticles are randomly immobilized on at least a portion of a substrate. A detection scheme is performed to detect the marker associated with the microparticle and the identity of the probe, and any target bound to the probe.

Abstract: A continuous wave ranging system, comprising a modulator 2 for modulating an r.f. carrier wave in accordance with a pseudo random code, a transmitting antenna 5 for radiating the modulated signal towards a target, a receiving antenna 6 and receiver 7 for detecting the signal reflected back from the target, a correlator 8 for correlating the reflected signal with the transmitted code with a selected phase shift corresponding to the current range gate to be tested, whereby the range of the target from the system may be determined, a store 12 containing a plurality of different pseudo random codes, and selector means 13 arranged to supply to the modulator 2 and to the correlator 8 a code from the store 12 which code does not produce a breakthrough sidelobe in at least the next range gate or gates to be tested.

Abstract: A polypeptide factor derived from the thermophilic eubacterial species Thermus thermophilus has universal protein expression-assisting activity. The polypeptide factor has been named the CzrB protein active in full length or truncated form has the potential to act as a universal protein expression-assisting molecule which can increase the yields of all heterologous proteins produced in E. coli by a mechanism that is independent of the protein being expressed.

Abstract: Compositions (1) that provide a carrier (2) to covey a plurality of capsules (3) containing materials) (4) released to generate perceivable sensorial indicia discrete event occurrence and which can further provide perceivable sensorial reinforcers as incentives or disincentives to composition use coincident with such discrete events.

Abstract: A material encapsulation and release system having a first zone (1) containing a first amount of material (2) bound by a first capsule wall (3) and, if desired, a second zone (4) containing a second amount of material (5) bound by a second capsule wall (6), each capsule wall responsive to similar or dissimilar activation means (7) to release the first amount of material (2) in the first zone (1) and the second amount of material (5) in the second zone (4).

Abstract: Generally, compositions that provide, either individually or in combination, aqueous activated components conveyed in a non-aqueous carrier system, perceivable sensorial indicia of discrete event occurrence, or perceivable sensorial reinforcers to provide sensorial incentives or sensorial disincentives, to encourage or discourage, attainment of discrete event occurrence.

Abstract: A continuous wave ranging system, comprising a modulator 2 for modulating an r.f. carrier wave in accordance with a pseudo-random code 3, a transmitting antenna 5 for radiating the modulated signal towards a target, a receiving antenna 6 and receiver 7 for detecting the signal reflected back from the target, a correlator 8 for correlating the reflected signal with a transmitted code with a selected phase shift 9 corresponding to the current range gate to be tested, and means 10, 11, 12 for processing the range/amplitude data from the correlator 8 to discriminate between reflections due to the target and those due to other objects adjacent to the target.

Abstract: The invention relates to heterocyclic derivatives of formula (I) A—B—X1—T1(R2)—L1—T2(R3)—X2—Q??(I) or pharmaceutically-acceptable salts thereof, which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.

Abstract: A fencing system includes a rail having at least two metal wires ensheathed in a plastic web, an end connector having a face plate with two slots and a middle portion separating the two slots, the end connector having a front side and a rear side. A free end of the rail is disposed in the slotted end connector so that the rail runs from the front side of the connector through a first slot, around the middle portion, and then back through a second slot. A fastener pivotally attaches the end connector to a fence post. Also, a joining connector of similar construction as the end connector is used to secure the free ends of two rails. Methods for securing a rail to a connector and for securing the free ends of two rails to a joining connector are also disclosed.

Abstract: An inkjet printhead includes a housing defining an interior compartment. The housing includes a front or print face which presents an array of nozzles that are adapted to project drops of ink on a substrate as the substrate passes in front of the array. The front face defines a front air passage that surrounds at least a portion of the nozzle array to allow air flow between the exterior of the housing and the interior compartment. The housing defines at least one additional air passage constructed to allow air flow between the exterior of the housing and the interior compartment. The air passages are constructed to create positive air flow through the front passage which reduces the accumulation of debris around the orifice array. The printhead may also include a protective structure that extends across a portion of the front air passage to protect the orifice array from being damaged by materials, such as mail, that move past the printhead at high speeds during the printing operation.

Abstract: A safety battery disconnect system for disconnecting a vehicle battery from the electrical system of the vehicle when an impact exceeding a predetermined magnitude is detected while maintaining electrical power input from the battery to selected portions of the vehicle electrical system. The system includes a shock sensor connected to a latching switch interposed between the battery and the vehicle fused electrical input system and is preferably a unitary unit mounted on or in close proximity to the battery.

Abstract: A machine vision system has an illumination head (1) with seven rings of LEDs 2-8, each having a different elevational angle. Each ring is configured with a particular current level, thereby setting its intensity. Rings 3 and 4 are green and blue, the other rings being red. A controller controls illumination by varying one or a combination of elevation, azimuth quadrant (or 45° octant), intensity, and colour. For example an image may be captured with fully surrounding, North quadrant, South quadrant, East quadrant, and West quadrant illuminations. Alternatively, there may be both North-South illumination for one image and East-West for another.

Abstract: The invention relates to heterocyclic derivatives of formula (I)

Abstract: An aircraft radar and altimeter system, comprising a radio transmitter and a transmitting antenna for radiating a beam of radio energy, a radio receiver and receiving antenna for receiving radio energy reflected from the ground, processing means for comparing the signal received by the receiver with the signal transmitted by the transmitter and determined from the comparison the instantaneous altitude of the aircraft above the ground, and means for changing the direction of radiation of the beam relative to the aircraft to compensate for changes in the attitude of the aircraft relative to the horizontal about at least one of the fore and aft and side-to-side axes.

Abstract: The invention relates to heterocyclic derivatives of the formula (I): A—B—X1—T1(R2)—L1—T2(R3)—X2—Q or pharmaceutically acceptable salts thereof, which possess antithrombotic and anticoagulant properties due to their inhibition of Factor Xa and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.

Abstract: A continuous wave radar altimeter comprises a pulsed power control (4), operable when the signal-to-noise ratio of the received signal is likely to be too low, to pulse the transmitted power so that the power varies between a non-zero base level and a higher level. The receiver channel (13, 14) is switched off during each transmitted pulse.

Abstract: A continuous wave ranging system comprises a modulator for modulating an r.f. carrier signal in accordance with a pseudo random code, a transmitting antenna for radiating the signal towards a target, a receiving antenna and receiver for detecting the signal reflected from the target, a correlator for correlating the detected signal with the transmitted code with a selected phase shift corresponding to the current range gate to be tested, whereby the range of the target from the system may be determined, and filtering means for filtering from the output of the correlator those range gate amplitudes which vary with a frequency less than a predetermined value.

Abstract: Compounds of formula I ##STR1## and metabolically labile esters and amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.13, M.sup.2, X.sup.1, Z.sup.1, Z.sup.1a, X.sup.2 and A.sup.1 have the meanings given in the specification. The compounds are useful as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa. Novel intermediates are also disclosed.

Abstract: Compounds of formula I ##STR1## and metabolically labile esters and amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.13, M.sup.2, X.sup.1, Z.sup.1, Z.sup.1a, X.sup.2 and A.sup.1 have the meanings given in the specification. The compounds are useful as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa. Novel intermediates are also disclosed.