Patents by Inventor JOHN WEMMIE

JOHN WEMMIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODULATING THE ACID-SENSING ION CHANNEL (ASIC)
    Publication number: 20120015396
    Abstract: Novel compositions for modulating acid-sensing ion channels (ASIC) function comprising ASIC?, ASIC?, and BNC1 and derivatives thereof; methods for modulating ASIC function and methods for treating cognitive disorders and for memory enhancement using the novel compositions of the invention; and a method for increasing synaptic plasticity are described.
    Type: Application
    Filed: August 24, 2011
    Publication date: January 19, 2012
    Applicants: Department of Veteran's Affair, United States Technology Transfer Program, UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: MICHAEL J. WELSH, JOHN A. WEMMIE
  • METHOD AND COMPOSITIONS FOR TREATING AND PREVENTING SEIZURES BY MODULATING ACID-SENSING ION CHANNEL ACTIVITY
    Publication number: 20090291150
    Abstract: This invention provides novel methods and compositions for treating and preventing seizures by administration of ASIC1a receptor activating compounds. A novel method of assaying ASIC1a receptor activating compounds is included in the present invention. According to the invention applicants have demonstrated that seizure duration, intensity, and progression may be modulated by administration of an ASIC1a receptor activator which acts to increase the endogenous activity of ASIC1a receptors to mediate the effects of low pH in the CNS. The inventors have also found that the ASIC1a receptor activator may prevent such seizures altogether.
    Type: Application
    Filed: May 20, 2009
    Publication date: November 26, 2009
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: MICHAEL J. WELSH, JOHN A. WEMMIE, ADAM E. ZIEMANN
  • Novel compositions and methods for modulation of the acid-sensing ion channel (ASIC) for the treatment of anxiety and drug addiction
    Publication number: 20070197583
    Abstract: This invention provides novel compositions and methods for modulating acid-sensing ion channels (ASIC) function comprising ASIC and derivatives thereof; methods for modulating ASIC function and methods for treating anxiety or anxiety disorders and drug addiction using the novel compositions of the invention; and a method for increasing synaptic plasticity are described.
    Type: Application
    Filed: September 10, 2003
    Publication date: August 23, 2007
    Inventors: Michael Welsh, John Wemmie
  • NOVEL COMPOSITIONS AND METHODS FOR MODULATING THE ACID-SENSING ION CHANNEL (ASIC)
    Publication number: 20070087964
    Abstract: Novel compositions for modulating acid-sensing ion channels (ASIC) function comprising ASIC?, ASIC?, and BNC1 and derivatives thereof; methods for modulating ASIC function and methods for treating cognitive disorders and for memory enhancement using the novel compositions of the invention; and a method for increasing synaptic plasticity are described.
    Type: Application
    Filed: August 14, 2006
    Publication date: April 19, 2007
    Applicants: UNIVERSITY OF IOWA RESEARCH FOUNDATION, DEPARTMENT OF VETERAN'S AFFAIRS, UNITED STATES
    Inventors: MICHAEL WELSH, JOHN WEMMIE
  • Novel compositions and methods for modulating the acid-sensing ion channel (ASIC)
    Publication number: 20030186860
    Abstract: Novel compositions for modulating acid-sensing ion channels (ASIC) function comprising ASIC&agr;, ASIC&bgr;, and BNC1 and derivatives thereof; methods for modulating ASIC function and methods for treating cognitive disorders and for memory enhancement using the novel compositions of the invention; and a method for increasing synaptic plasticity are described.
    Type: Application
    Filed: March 29, 2002
    Publication date: October 2, 2003
    Inventors: Michael J. Welsh, John A. Wemmie