Abstract: A chemical compound is provided according to general formula (1):

Abstract: A wall panel system includes a plurality of wall panels, and one or more hat channels each configured to be attached to a supporting wall and each configured to be attached to the one or more of the plurality of wall panels. The one or more hat channels maintains a predetermined distance between the supporting wall and the plurality of wall panels. One or more keeper members are each configured to be attached to one of the one or more hat channels. When the wall panel system is assembled, each keeper member at least partially supports the weight of the one or more wall panels.

Abstract: This invention concerns an additive manufacturing apparatus for building objects by layerwise consolidation of material. The apparatus comprises a build chamber 101 containing a working area, a plurality of high energy beams 133, 233 for consolidating material deposited in the working area in layers and an optical unit 135 for controlling transmission of the high energy beams onto material in the working area. The optical unit 135 comprises a plurality of independently controllable optical elements 141, 241 each optical element 141, 241 for controlling transmission of at least one of the high energy beams onto the material in the working area, the optical unit 135 movable in the build chamber 101.

Abstract: A method of putting a feature of interest on an object and an optical inspection system of a non-contact probe mounted on a positioning apparatus in a desired relationship. The method includes: a) identifying a target point of interest on the object to be inspected by arranging the non-contact probe and object at a first relative configuration at which a marker feature, projected by the non-contact probe along a projector axis that is not coaxial with the optical inspection system's optical axis, identifies the target point of interest; and b) subsequently moving the non-contact probe and/or object so as to put them at a second relative configuration at which the target point of interest and optical inspection system are at the desired relationship, in which the positioning apparatus is configured to guide such motion in accordance with the control path.

Abstract: A laser beam scanner including a laser beams positioning optic, a plurality of optical fibres for delivering a plurality of laser beams and a fibre termination optic aligned to direct the laser beams from output ends of the plurality of optical fibres to the laser beams positioning optic. The laser beams positioning optic is movable relative to the fibre termination optic to scan the laser beams across a working surface.

Abstract: Measurement cavities described herein include a cylindrical chamber having a first open end and a second open end; a first cap covering the first open end of the cylindrical chamber and a second cap covering the second open end of the cylindrical chamber, wherein the first and second caps hermetically seal the cylindrical chamber and wherein the first cap is rigidly coupled to the second cap; and a wafer holder positioned within and coupled to the cylindrical chamber. The measurement cavity has a mass m, a stiffness k, and a damping constant c configured such that the transmissibility ? x F ? of an input force at 60 Hz in the measurement cavity is reduced by a factor of at least 10 and the measurement cavity has a natural frequency of greater than 300 Hz.

Abstract: An improved music fingering aid has at least one decal fittable overlaying the fingerboard and attachable to the neck of a stringed instrument. The decal includes string identifier indicators, a graduated position indicators series, and a plurality of interval demarcations that employ distinct colors for visual distinction. The indicators do not pair particular notes with particular colors. Instead the improved music fingering aid associates music theory with muscle memory to ensure sounded notes are played in near perfect pitch and, when playing ensemble, in tempered pitch. Contemplation and improved association of music theory is thereby enabled.

Abstract: The present disclosure provides method of detecting senescent cells in a cell sample and methods of treating a disease, disorder, or condition associated with senescence in a subject by administering at least one senolytic agent to the subject.

Abstract: It is provided a chemical compound according to general formula (1)

Abstract: The methods disclosed herein include recording at near-vertical first and second measurement positions respective first and second interferograms of the photomask surface and defining a difference map as the difference between the first and second interferograms. Respective first and second normal forces on the photomask are also measured at the first and second measurement positions. The change in the normal force is used define a scaling factor, which is applied to the difference map to define a scaled difference map. A compensated flatness measurement with a reduced shape contribution due to gravity is obtained by subtracting the scaled difference map from the first interferogram. An interferometer-based flatness measurement system is also disclosed.

Abstract: Described herein are technologies related to constructing supplemental content items that summarize electronic landing pages. A sequence to sequence model that is configured to construct supplemental content items is trained based upon a corpus of electronic landing pages and supplemental content items that have been constructed by domain experts, wherein each landing page has a respective supplemental content item assigned thereto. The sequence to sequence model is additionally trained using self critical sequence training, where estimated click through rates of supplemental content items generated by the sequence to sequence model are employed to train the sequence to sequence model.

Abstract: A method and system for forming a holographic structure in a material. The holographic structure is configured to project a selected target image in the far field under illumination of the holographic structure by a laser. The method calculates a modified design for the holographic structure that encodes a unique identifier within the holographic structure for projecting the target image. The method modifies the material by mapping features corresponding to the modified design into the material so as to form the holographic structure. A basic check of the authenticity of the material is performed by checking whether a projected replica of the target image is as expected. A more detailed check of the authenticity of the material is performed by directly inspecting the features in the holographic structure.

Abstract: A chemical compound is provided according to general formula (1):

Abstract: The methods disclosed herein include recording at near-vertical first and second measurement positions respective first and second interferograms of the photomask surface and defining a difference map as the difference between the first and second interferograms. Respective first and second normal forces on the photomask are also measured at the first and second measurement positions. The change in the normal force is used define a scaling factor, which is applied to the difference map to define a scaled difference map. A compensated flatness measurement with a reduced shape contribution due to gravity is obtained by subtracting the scaled difference map from the first interferogram. An interferometer-based flatness measurement system is also disclosed.

Abstract: An improved music fingering aid has at least one decal fittable overlying the fingerboard and attachable to the neck of a stringed instrument. The decal includes string identifier indicia, a graduated position indicia series, and a plurality of interval demarcations that employ distinct colors for visual distinction. The indicia do not pair particular notes with particular colors. Instead the improved music fingering aid associates music theory with muscle memory to ensure sounded notes are played in near perfect pitch and, when playing ensemble, in tempered pitch. Contemplation and improved association of music theory is thereby enabled.

Abstract: This invention concerns an additive manufacturing apparatus for building objects by layerwise consolidation of material. The apparatus comprises a build chamber 101 containing a working area, a plurality of high energy beams 133, 233 for consolidating material deposited in the working area in layers and an optical unit 135 for controlling transmission of the high energy beams onto material in the working area. The optical unit 135 comprises a plurality of independently controllable optical elements 141, 241 each optical element 141, 241 for controlling transmission of at least one of the high energy beams onto the material in the working area, the optical unit 135 movable in the build chamber 101.

Abstract: An additive manufacturing apparatus for building objects by layerwise consolidation of material. The apparatus includes a build chamber containing a working area, a plurality of high energy beams for consolidating material deposited in the working area in layers and an optical unit for controlling transmission of the high energy beams onto material in the working area. The optical unit includes a plurality of independently controllable optical elements each optical element for controlling transmission of at least one of the high energy beams onto the material in the working area, the optical unit movable in the build chamber.

Abstract: A method of putting a feature of interest on an object and an optical inspection system of a non-contact probe mounted on a positioning apparatus in a desired relationship. The method includes: a) identifying a target point of interest on the object to be inspected by arranging the non-contact probe and object at a first relative configuration at which a marker feature, projected by the non-contact probe along a projector axis that is not coaxial with the optical inspection system's optical axis, identifies the target point of interest; and b) subsequently moving the non-contact probe and/or object so as to put them at a second relative configuration at which the target point of interest and optical inspection system are at the desired relationship, in which the positioning apparatus is configured to guide such motion in accordance with the control path.

Abstract: A method of forming an optical device comprises applying a laser beam to a target area of the surface so as to selectively heat material of the surface thereby to provide transfer of material due to a surface tension gradient, wherein the surface is such that, when liquid, parts of the surface at higher temperatures have a higher surface tension than adjacent parts of the surface at lower temperatures.

Abstract: The present invention relates to substituted 2-(chroman-6-yloxy)-thiazoles of the formula I, in which Ar, R2, R3 and R4 are as defined in the claims. The compounds of the formula I are inhibitors of the sodium-calcium exchanger (NCX), especially of the sodium-calcium exchanger of subtype 1 (NCX1), and are suitable for the treatment of diverse disorders in which intracellular calcium homeostasis is disturbed, such as arrhythmias, heart failure and stroke. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use as pharmaceuticals, and pharmaceutical compositions comprising them.