Patents by Inventor John Whitelock

John Whitelock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Perlecan and growth factor for wound and cutaneous injury healing
    Patent number: 7772204
    Abstract: The present disclosure describes the use of the heparan sulfate proteoglycan perlecan as treatment for the improvement of wound healing and/or cutaneous injury.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: August 10, 2010
    Assignee: Agenta Biotechnologies, Inc.
    Inventors: Arthur A. DeCarlo, John Whitelock
  • Drive tumbler
    Publication number: 20100081532
    Abstract: A drive tumbler comprises a hub having attached thereto a plurality of replaceable rim segments. The rim segments are supported by a plurality of raised blocks that are formed integral with the hub and serve to absorb the shear forces to which the tumbler is subject during operation.
    Type: Application
    Filed: September 18, 2009
    Publication date: April 1, 2010
    Applicant: Excel Foundry and Machine, Inc.
    Inventors: Michael V. McCafferty, John Whitelock, Scott Kreger, Troy Miller
  • Wound and cutaneous injury healing with a nucleic acid encoding a proteoglycan polypeptide
    Patent number: 7666852
    Abstract: The present disclosure provides nucleic acid constructs encoding one or more polypeptides containing at least one glycosaminoglycan chain, such as, but not limited to, a proteoglycan polypeptide, and methods for delivering to the site of a wound or cutaneous injury at least one nucleic acid construct encoding one or more such polypeptides, such that the expressed polypeptide is glycated by glycosaminoglycan chains through the normal physiological processes of the subject at the site of administration to produce a functional proteoglycan polypeptide for the healing of the wound or other cutaneous injury. The delivered nucleic acid construct is transcribed, translated and post-translationally modified by the addition of glycosaminoglycan chains (referred herein as “decoration” or “glycation”) to produce a decorated polypeptide.
    Type: Grant
    Filed: May 14, 2007
    Date of Patent: February 23, 2010
    Assignee: Agenta Biotechnologies, Inc.
    Inventors: Arthur A. Decarlo, John Whitelock, April L. Ellis
  • Wound and cutaneous injury healing with a nucleic acid encoding perlecan
    Patent number: 7488719
    Abstract: A description of a biomolecule named Perlecan which is added internally or topically, or is expressed from exogenously added nucleic acids, as a whole or in part, to a healing wound to improve the success of wound healing is disclosed. Relevant embodiments for this patent technology are described.
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: February 10, 2009
    Assignee: Agenta Biotechnologies, Inc.
    Inventors: Arthur A. DeCarlo, John Whitelock
  • Wound and cutaneous injury healing with a nucleic acid encoding a proteoglycan polypeptide
    Publication number: 20080247995
    Abstract: The present disclosure provides nucleic acid constructs encoding one or more polypeptides containing at least one glycosaminoglycan chain, such as, but not limited to, a proteoglycan polypeptide, and methods for delivering to the site of a wound or cutaneous injury at least one nucleic acid construct encoding one or more such polypeptides, such that the expressed polypeptide is glycated by glycosaminoglycan chains through the normal physiological processes of the subject at the site of administration to produce a functional proteoglycan polypeptide for the healing of the wound or other cutaneous injury. The delivered nucleic acid construct is transcribed, translated and post-translationally modified by the addition of glycosaminoglycan chains (referred herein as “decoration” or “glycation”) to produce a decorated polypeptide.
    Type: Application
    Filed: May 14, 2007
    Publication date: October 9, 2008
    Inventors: Arthur A. Decarlo, John Whitelock, April L. Ellis
  • Wound and cutaneous injury healing with a nucleic acid encoding perlecan
    Patent number: 7141551
    Abstract: A description of a biomolecule named Perlecan which is added internally or topically, or is expressed from exogenously added nucleic acids, as a whole or in part, to a healing wound to improve the success of wound healing is disclosed. Relevant embodiments for this patent technology are described.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: November 28, 2006
    Inventors: Arthur A. DeCarlo, John Whitelock