Abstract: This application provides methods and systems for optimizing individualized instruction and assessment. In one embodiment a system for optimizing individualized instruction and assessment is provided. The system includes a user base component, a knowledge base component, a standards base component and an inference engine module. The user base component contains an electronic student record data for an individual. The knowledge base component contains knowledge management data. The standards base component contains curriculum data and criteria data. The inference engine module uses the electronic student record of the individual, knowledge management data and curriculum data and criteria data to create an individualized lesson plan for the individual.