Abstract: A cover for a mini C-arm machine having a detector is designed to maintain a sterile field for a detector screen. The cover includes a panel having at least three integral sides, two being spaced-apart parallel to each other. The cover includes a pair of straps. One of the straps has an end portion fixed to one of the two parallel sides. The other strap has an end portion fixed to the other of the two parallel sides. The cover includes a hook-and-loop closure mechanism having a hooked portion and a looped portion. Each strap has a fixed end portion and a free, opposite end portion. The free end portion of one strap includes the hooked portion and the free end portion of the other strap includes the looped portion. Each closure portion is sized, when the closure portions are engaged, to retain the panel against the detector.