Patents by Inventor John William Secombe

John William Secombe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lithium detection in liquid biological samples and reagents therefor
    Patent number: 7241623
    Abstract: A method of detecting soluble lithium in a liquid biological sample comprising combining: (a) an amount of the biological sample; (b) 2,3,7,8,12,13,17,18-octobromo-5,10,15,20-tetrakis(4-sulphonatophenyl) porphyrin; (c) alkali; (d) detergent; (e) chelating agent; and (f) optionally a suitable solvent; to produce a test sample; detecting absorbance change of the test sample relative to a lithium deficient standard sample at a wavelength of between about 475 nm and about 485 nm, between about 515 nm and about 525 nm or simultaneously between about 475 nm and about 485 nm and between about 515 nm and about 525 nm, wherein absorbance change indicates presence of soluble lithium in the biological sample. Also disclosed is a method of quantitatively measuring soluble lithium ions in a biological sample and a reagent for use in such methods.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: July 10, 2007
    Assignee: Seba Diagnostics Pty. Ltd.
    Inventors: Nicholas Dennis Henry Balazs, John William Secombe
  • Lithium detection in liquid biological samples and reagents therefor
    Publication number: 20030186450
    Abstract: A method of detecting soluble lithium in a liquid biological sample comprising combining: (a) an amount of the biological sample; (b) 2,3,7,8,12,13,17,18-octobromo-5,10,15,20-tetrakis(4-sulphonatophenyl) porphyrin; (c) alkali; (d) detergent; (e) chelating agent; and (f) optionally a suitable solvent; to produce a test sample; detecting absorbance change of the test sample relative to a lithium deficient standard sample at a wavelength of between about 475 nm and about 485 nm, between about 515 nm and about 525 nm or simultaneously between about 475 nm and about 485 nm and between about 515 nm and about 525 nm, wherein absorbance change indicates presence of soluble lithium in the biological sample. Also disclosed is a method of quantitatively measuring soluble lithium ions in a biological sample and a reagent for use in such methods.
    Type: Application
    Filed: June 4, 2003
    Publication date: October 2, 2003
    Inventors: Nicholas Dennis Henry Balazs, John William Secombe