Patents by Inventor John William Shultz
John William Shultz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6730479Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: February 22, 2001Date of Patent: May 4, 2004Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch
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Patent number: 6703211Abstract: Processes and materials are disclosed for the detection of cells using endogenous enzymes to catalyze the conversion of AMP and/or ADP to ATP in the presence of a high energy phosphate donor other than ADP, then the ATP is detected using luciferase.Type: GrantFiled: September 15, 1999Date of Patent: March 9, 2004Assignee: Promega CorporationInventors: John William Shultz, Keith V. Wood, Mary Hall, Tamara Sue Pratt
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Patent number: 6653078Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences using a multiplex assay format. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: February 20, 2001Date of Patent: November 25, 2003Assignee: Promega CorporationInventors: Martin K. Lewis, Daniel Kephart, Richard Byron Rhodes, John William Shultz, Donna Leippe, Michelle Mandrekar, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Keith V. Wood, Roy Welch
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Publication number: 20030203358Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined exogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: ApplicationFiled: February 9, 2001Publication date: October 30, 2003Applicant: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch
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Publication number: 20030194699Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences using a multiplex assay format. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, genotyping, medical marker diagnostics, and the like.Type: ApplicationFiled: February 20, 2001Publication date: October 16, 2003Applicant: Promega CorporationInventors: Martin K. Lewis, Daniel Kephart, Richard Byron Rhodes, John William Shultz, Donna Leippe, Michelle Mandrekar, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Keith V. Wood, Roy Welch
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Publication number: 20030077621Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined endogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, spieciation, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: ApplicationFiled: May 20, 2002Publication date: April 24, 2003Applicant: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch
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Publication number: 20030022163Abstract: Materials and methods are disclosed for the detection of a desired nucleic acid that contains multiple repeats of a predetermined nucleic acid target sequence, typically using nucleic acid hybridization methods. Nucleic acid hybrid detection methods can be used to qualitatively and quantitatively analyze for the presence of a desired nucleic acid. Applications of the disclosed materials and methods include the detection of nucleic acid without the need for nucleic acid amplification or isolation of a fragment containing nucleic acid target.Type: ApplicationFiled: December 15, 2000Publication date: January 30, 2003Inventors: Michelle N. Mandrekar, Allan Tereba, John William Shultz
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Patent number: 6484072Abstract: An embedded terrain awareness warning system for aircraft being flown by a pilot includes a signal processing component, a protection component and a pilot vehicle interface. A method for providing an embedded terrain awareness warning system for aircraft being flown by a pilot includes providing a signal processing component, a protection component and a pilot vehicle interface. The signal processing component communicates with three-dimensional digital terrain elevation data and is able to take input data from aircraft sensors, aircraft computers or navigation systems and determine aircraft position and velocity. The protection component is in communication with the signal processing unit such that the protection component is able to determine if a potential controlled flight into terrain exists and is able to predict a recovery flight path to avoid terrain.Type: GrantFiled: September 28, 2001Date of Patent: November 19, 2002Assignee: The United States of America as represented by the Secretary of the NavyInventors: Thomas E. Anderson, Thomas J. Hanrahan, Charles W. Shaffer, John William Shultz
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Patent number: 6391551Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined endogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: August 25, 1999Date of Patent: May 21, 2002Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch
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Patent number: 6312902Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: September 27, 1999Date of Patent: November 6, 2001Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Roy Welch
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Publication number: 20010031470Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: ApplicationFiled: February 22, 2001Publication date: October 18, 2001Applicant: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch
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Patent number: 6277578Abstract: The detection of enhanced, targeted predetermined nucleic acid sequences in nucleic acid target hybrids, and the various applications of target nucleic acid enhancement are disclosed.Type: GrantFiled: October 29, 1999Date of Patent: August 21, 2001Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Christine Ann Andrews, James Robert Hartnett, Roy Welch
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Patent number: 6270974Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined exogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: September 27, 1999Date of Patent: August 7, 2001Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch
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Patent number: 6270973Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences using a multiplex assay format. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: September 27, 1999Date of Patent: August 7, 2001Assignee: Promega CorporationInventors: Martin K. Lewis, Daniel Kephart, Richard Byron Rhodes, John William Shultz, Donna Leippe, Michelle Mandrekar, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Keith V. Wood, Roy Welch
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Patent number: 6268146Abstract: Mass spectrometric, absorbance spectroscopic and fluorescence spectroscopic processes are disclosed to detect the depolymerization of a nucleic acid hybrid in order to qualitatively and quantitatively assay for the presence of a predetermined nucleic acid target. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like, including multiplexed assays.Type: GrantFiled: November 22, 1999Date of Patent: July 31, 2001Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Michelle Mandrekar, Donna Leippe, Roderick R. Smith, Jr., Roy Welch
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Patent number: 6235480Abstract: Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.Type: GrantFiled: July 21, 1999Date of Patent: May 22, 2001Assignee: Promega CorporationInventors: John William Shultz, Martin K. Lewis, Donna Leippe, Michelle Mandrekar, Daniel Kephart, Richard Byron Rhodes, Christine Ann Andrews, James Robert Hartnett, Trent Gu, Ryan J. Olson, Keith V. Wood, Roy Welch