Publication number: 20100273816
Abstract: Disclosed are quinazoline-based modulators of Liver X receptors (LXRs) and related methods. The modulators include compounds of formula (I): in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, W, W1, W2, W3, A, Ra, Ra?, Rb, Rb?, Rc, Rd, Rd?, Re, Rf, Rg, Rh, Ri Rj, Rk, Rm, Rn, Ro, Rp, Rq, and n, can be, independently, as defined anywhere herein. In general, these compounds can be used for treating or preventing one or more diseases, disorders, conditions or symptoms mediated by LXRs.
Type:
Application
Filed:
May 15, 2008
Publication date:
October 28, 2010
Inventors:
Ronald Charles Bernotas, John William Ullrich, Jeremy Mark Travins, Jay Edward Wrobel, Rayomand Jal Unwalla
