Patents by Inventor John Winterbottom
John Winterbottom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10322209Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: GrantFiled: May 8, 2018Date of Patent: June 18, 2019Assignee: Warsaw Orthopedic, Inc.Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd Boyce, Lawrence A. Shimp
-
Patent number: 10080661Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: GrantFiled: May 9, 2016Date of Patent: September 25, 2018Assignee: Warsaw Orthopedic, Inc.Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
-
Publication number: 20180250442Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: ApplicationFiled: May 8, 2018Publication date: September 6, 2018Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd Boyce, Lawrence A. Shimp
-
Patent number: 10028837Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.Type: GrantFiled: May 6, 2016Date of Patent: July 24, 2018Assignee: Warsaw Orthopedic, Inc.Inventors: Guobao Wei, Keyvan Behnam, Nanette Forsyth, John Winterbottom, James Beisser, Todd Boyce, Mohamed Attawia, Cristy J. Richards, Lawrence A. Shimp
-
Patent number: 9993579Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: GrantFiled: July 6, 2017Date of Patent: June 12, 2018Assignee: Warsaw Orthopedic, Inc.Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
-
Patent number: 9849215Abstract: Methods for forming implantable compositions are provided. In some embodiments, the methods include (i) providing a gel base, (ii) adding water and a hydrating agent to the gel base to form a mixture, (iii) reducing the water content of the mixture; and (iv) adding a delivered material before, during, and/or after step (ii) or (iii). The water content is reduced to about 5% or less by weight of the implantable composition.Type: GrantFiled: February 19, 2016Date of Patent: December 26, 2017Assignee: Warsaw Orthopedic, Inc.Inventors: Christina Mossaad, Lawrence A. Shimp, Guobao Wei, John Winterbottom
-
Publication number: 20170304496Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: ApplicationFiled: July 6, 2017Publication date: October 26, 2017Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
-
Patent number: 9789223Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: GrantFiled: May 2, 2016Date of Patent: October 17, 2017Assignee: Warsaw Orthopedic, Inc.Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
-
Patent number: 9492278Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.Type: GrantFiled: July 10, 2008Date of Patent: November 15, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Guobao Wei, Nanette Forsyth, John Winterbottom, James Beisser, Todd M. Boyce, Sigurd H. Berven, Randal R. Betz, Michael F. O'Brien, Alexis P. Shelokov
-
Publication number: 20160250025Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: ApplicationFiled: May 9, 2016Publication date: September 1, 2016Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
-
Publication number: 20160250038Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.Type: ApplicationFiled: May 6, 2016Publication date: September 1, 2016Inventors: Guobao Wei, Keyvan Behnam, Nanette Forsyth, John Winterbottom, James Beisser, Todd Boyce, Mohamed Attawia, Cristy J. Richards, Lawrence A. Shimp
-
Publication number: 20160243284Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: ApplicationFiled: May 2, 2016Publication date: August 25, 2016Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
-
Patent number: 9415136Abstract: An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation.Type: GrantFiled: May 23, 2014Date of Patent: August 16, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Keyvan Behnam, Nanette Forsyth, James Russell, John Winterbottom, Todd Boyce
-
Publication number: 20160166729Abstract: Methods for forming implantable compositions are provided. In some embodiments, the methods include (i) providing a gel base, (ii) adding water and a hydrating agent to the gel base to form a mixture, (iii) reducing the water content of the mixture; and (iv) adding a delivered material before, during, and/or after step (ii) or (iii). The water content is reduced to about 5% or less by weight of the implantable composition.Type: ApplicationFiled: February 19, 2016Publication date: June 16, 2016Inventors: Christina Mossaad, Lawrence A. Shimp, Guobao Wei, John Winterbottom
-
Patent number: 9358113Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.Type: GrantFiled: July 10, 2008Date of Patent: June 7, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Guobao Wei, Keyvan Behnam, Nanette Forsyth, John Winterbottom, James Beisser, Todd M. Boyce
-
Patent number: 9333080Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: GrantFiled: August 21, 2013Date of Patent: May 10, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd M. Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
-
Patent number: 9333082Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.Type: GrantFiled: September 5, 2008Date of Patent: May 10, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Guobao Wei, Keyvan Behnam, Nanette Forsyth, John Winterbottom, James Beisser, Todd M. Boyce, Mohamed Attawia, Cristy J. Richards, Lawrence A. Shimp
-
Patent number: 9327052Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: GrantFiled: April 22, 2013Date of Patent: May 3, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: David A. Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
-
Patent number: 9308292Abstract: A composite osteoimplant. The osteoimplant includes a polymer and bone-derived particles. The composite is adapted and constructed to be formable during or immediately prior to implantation and to be set after final surgical placement.Type: GrantFiled: November 5, 2007Date of Patent: April 12, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: John Winterbottom, David Kaes
-
Patent number: 9265830Abstract: Methods for forming implantable compositions are provided. In some embodiments, the methods include (i) providing a gel base, (ii) adding water and a hydrating agent to the gel base to form a mixture, (iii) reducing the water content of the mixture; and (iv) adding a delivered material before, during, and/or after step (ii) or (iii). The water content is reduced to about 5% or less by weight of the implantable composition.Type: GrantFiled: April 20, 2011Date of Patent: February 23, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Christina Mossaad, Lawrence A. Shimp, Guobao Wei, John Winterbottom