Patents by Inventor John X. He

John X. He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Endotherlin antagonists
    Patent number: 5382569
    Abstract: Novel antagonists of endothelin are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in treating elevated levels of endothelin, acute and chronic renal failure, hypertension, myocardial infarction, metabolic, endocrinological, neurological disorders, congestive heart failure, endotoxic shock, subarachnoid hemorrhage, arrhythmias, asthma, preeclampsia, Raynaud's disease, percutaneous transluminal coronary angioplasty or restenosis, angina, cancer, pulmonary hypertension, ischemic disease, gastric mucosal damage, ischemic bowel disease, and diabetes.
    Type: Grant
    Filed: December 21, 1992
    Date of Patent: January 17, 1995
    Assignee: Warner-Lambert Company
    Inventors: Wayne L. Cody, Patricia DePue, Annette M. Doherty, John X. He, Michael D. Taylor
  • Linear and monocyclic endothelin antagonists
    Patent number: 5260276
    Abstract: Novel linear and monocyclic antagonists of endothelin are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling hypertension, myocardial infarction, metabolic, endocrinological, and neurological disorders, congestive heart failure, endotoxic shock, subarachnoid hemorrhage, arrhythmias, asthma, acute renal failure, preeclampsia, and diabetes.
    Type: Grant
    Filed: June 14, 1991
    Date of Patent: November 9, 1993
    Assignee: Warner-Lambert Company
    Inventors: Wayne L. Cody, Annette M. Doherty, John X. He