Patents by Inventor John Y. Chu

John Y. Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETERODIMERIC ANTIBODIES THAT BIND CD3 AND CLDN6
    Publication number: 20240132584
    Abstract: Provided herein are novel CLDN6 binding domains, and anti-CLDN6×anti-CD3 antibodies that include such CLDN6 binding domains. Also provided herein are methods of using such antibodies for the treatment of CLDN6-associated cancers.
    Type: Application
    Filed: July 5, 2023
    Publication date: April 25, 2024
    Inventors: Matthew S. Faber, Sung-Hyung Lee, Yoon Kyung Kim, Jing Qi, Kendra N. Avery, Seung Y. Chu, Alex Nisthal, Matthew J. Bernett, John R. Desjarlais, Chad Borchert
  • Vitamin D metabolism inhibitor
    Patent number: 4481198
    Abstract: This invention provides a novel vitamin D derivative, namely a 24-oxime derivative of vitamin D.sub.3, and a process for its preparation. The compound of this invention is an effective inhibitor of vitamin D-25-hydroxylation and markedly suppresses the formation of the physiologically active vitamin D metabolites. The compound would thus find use as an effective antagonist of vitamin D activation, and for treating hypercalcemic conditions resulting from metabolic, bone, or neoplastic diseases, or from vitamin D intoxication.
    Type: Grant
    Filed: February 13, 1984
    Date of Patent: November 6, 1984
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Heinrich K. Schnoes, John Y. Chu, Bruce D. Kabakoff