Abstract: A digital processing-in-memory (DPIM) macro operates to perform memory readout and multiply-accumulate (MAC) computation in a cycle-constrained design. Access on a local bit-line through a self-timed circuit that integrates pre-charge and word-line enable is performed in a single clock cycle. Further, local bit-line parasitic capacitance is utilized for weight retention during multiple compute clock cycles. A high-skew inverter, operating as a local sense amplifier, further optimizes read access times with minimal area impact, enhancing access speeds.

Abstract: An isolated cancer-targeting peptide that includes at least two copies of the amino acid sequence PFLP (SEQ ID NO: 1) or PFLF (SEQ ID NO: 2). Also disclosed is a pharmaceutical composition for treating cancer. The composition contains the isolated cancer-targeting peptide and an anti-cancer agent. Further disclosed is a bispecific anti-cancer antibody that includes the isolated cancer-targeting peptide and an antigen-binding peptide that stimulates T cell activity. Methods are provided for treating cancer by administering the pharmaceutical composition or the bispecific anti-cancer antibody. Further provided is a method for diagnosing cancer by administering a radionuclide-labeled cancer-targeting peptide to an individual and imaging a location of the radionuclide.

Abstract: A method for providing messaging services includes accessing an organization structure of an organization; creating chat services user accounts in response to the organization structure of the organization; creating groups of users in response to the organization structure of the organization, the groups comprising a chat group and a broadcast chat group; wherein the chat group provides bidirectional messaging from each member of the chat group to each other member of the chat group; wherein broadcast chat group provides unidirectional messaging from a broadcast group owner to each other member of the broadcast chat group.

Abstract: An isolated cancer-targeting peptide that includes at least two copies of the amino acid sequence PFLP (SEQ ID NO: 1) or PFLF (SEQ ID NO: 2). Also disclosed is a pharmaceutical composition for treating cancer. The composition contains the isolated cancer-targeting peptide and an anti-cancer agent. Further disclosed is a bispecific anti-cancer antibody that includes the isolated cancer-targeting peptide and an antigen-binding peptide that stimulates T cell activity. Methods are provided for treating cancer by administering the pharmaceutical composition or the bispecific anti-cancer antibody. Further provided is a method for diagnosing cancer by administering a radionuclide-labeled cancer-targeting peptide to an individual and imaging a location of the radionuclide.

Abstract: The embodiments disclose a method including fabricating a pool filter guard apparatus including a pool filter guard debris screen and spreader anchor apparatus installation device for coupling to the pool filter guard apparatus for installing into a pool skimmer to prevent debris from clogging a pool skimmer basket, fabricating a pool filter guard angular safety module with infrared detection sensors, chemical testing devices, temperature sensors, WIFI and cellular connectivity, a digital processor, digital memory device, panoramic camera for reporting pool conditions to a pool owner and for transmitting alerts on potential unintentional drowning, and creating a pool filter guard digital app for installation in a user digital device for receiving real-time pool condition reports and alerts transmitted from the pool filter guard angular safety module.

Abstract: The present invention provides monoclonal antibodies or the antigen-binding portion thereof, that bind to a feto-embryonic dedifferentiated antigen, such as Leucine-rich Repeat Neuronal Protein 1 (LRRN1), a surface glycoprotein that is expressed abundantly on the surface of human embryonic stem cells prior to differentiation into embryoid bodies. Also disclosed herein are the uses of the novel LRRN1 antibodies.

Abstract: Embodiments of the present disclosure relate generally to systems and methods for reducing sound in vacuum toilets. In one example, multiple rinse injections are used at appropriately timed intervals in order to reduce the vacuum flush sound levels.

Abstract: A method for providing messaging services includes accessing an organization structure of an organization; creating chat services user accounts in response to the organization structure of the organization; creating groups of users in response to the organization structure of the organization, the groups comprising a chat group and a broadcast chat group; wherein the chat group provides bidirectional messaging from each member of the chat group to each other member of the chat group; wherein broadcast chat group provides unidirectional messaging from a broadcast group owner to each other member of the broadcast chat group.

Abstract: A method for maintaining packet's source network identification information while aggregating packets from a plurality of networks is provided. An ingress packet is processed to extract a plurality of packet header fields and port identifier. A first hash index is generated by hashing information associated with the plurality of packet header fields. The extracted port identifier is stored in a hash table using the generated first hash index. The ingress packet is forwarded to one or more inline tool devices. An egress packet received from the one or more inline tools is processed to extract the plurality of packet header fields. A second hash index is generated by hashing information associated with the plurality of packet header fields. The port identifier is retrieved from the hash table based on the generated second hash index. The egress packet is transmitted to a switching device based on the retrieved port identifier.

Abstract: Embodiments of the present invention provide a water management system for use on board a passenger transport vehicle. The water management system may be used to address and manage excess humidity, water leaks, or any other instance when water or other liquid may collect at a certain location. The disclosure provides a system for managing excess water and for optionally delivering the water to another location. The removal location may be a disposal outlet or it may be a beneficial use of the collected water on-board the vehicle.

Abstract: Kits for detecting cancer, including an agent for measuring LRRN1 antibody and a label indicating that the reagent for measuring LRRN1 antibody is for detecting cancer are disclosed. Methods for detecting cancer in a subject, including the steps of measuring the level of LRRN1 antibody, wherein a higher LRRN1 antibody level in the subject compare to a control sample, indicates the presence of cancer, are also provided.

Abstract: Embodiments relate generally to flush plates having noncircular openings. In a specific example, the flush plate has a shark-fin shaped opening with an extending fin along a tail portion.

Abstract: The present invention provides methods of inhibiting or reducing the growth of cancer cells in a subject, by administering a therapeutic effective amount of Puf-A inhibitor, whereby the symptoms and signs of cancer in the subject are reduced. Also provided are polynucleotides and vectors encoding the shRNAs which target Puf-A expression, which are useful for the treatment of cancer.

Abstract: Embodiments of the present invention provide a water management system for use on board a passenger transport vehicle. The water management system may be used to address and manage excess humidity, water leaks, or any other instance when water or other liquid may collect at a certain location. The disclosure provides a system for managing excess water and for optionally delivering the water to another location. The removal location may be a disposal outlet or it may be a beneficial use of the collected water on-board the vehicle.

Abstract: An immunogenic composition containing a glycan conjugate including a carrier protein, and a glycan including Globo H, an immunogenic fragment thereof, or stage-specific embryonic antigen-4 (SSEA-4), wherein the glycan is conjugated with the carrier protein through a linker.

Abstract: A method for maintaining packet's source network identification information while aggregating packets from a plurality of networks is provided. An ingress packet is processed to extract a plurality of packet header fields and port identifier. A first hash index is generated by hashing information associated with the plurality of packet header fields. The extracted port identifier is stored in a hash table using the generated first hash index. The ingress packet is forwarded to one or more inline tool devices. An egress packet received from the one or more inline tools is processed to extract the plurality of packet header fields. A second hash index is generated by hashing information associated with the plurality of packet header fields. The port identifier is retrieved from the hash table based on the generated second hash index. The egress packet is transmitted to a switching device based on the retrieved port identifier.

Abstract: The present invention provides methods of inhibiting or reducing the growth of cancer cells in a subject, by administering a therapeutic effective amount of Puf-A inhibitor, whereby the symptoms and signs of cancer in the subject are reduced. Also provided are polynucleotides and vectors encoding the shRNAs which target Puf-A expression, which are useful for the treatment of cancer.

Abstract: Disclosed herein are structure-based methods for ligand optimization. The methods involve the selection of a candidate ligand from a structural library based on the binding energy of the ligand with a cancer cell-surface protein. The binding energy is estimated from parameters including polar and mon-polar interactions between the ligand and the surface protein. In this way, candidate ligand(s) with desirable binding affinity to the cancer cell-surface protein can be selected.

Abstract: Techniques for compressing data in a wireless network are provided. Data may be in the form of data packets that have one or more headers and a payload. One or more compression initiation criteria are used to determine whether to compress all data or certain data. Different data may be associated with different classes of service. Compression initiation criteria for data that belongs to one class of service may be different than compression initiation criteria for data that belongs to another class of service. Compression initiation criteria for data may be different than one or more compression halting criteria that are used to determine whether to cease compressing data. One type of compression involves use of synchronized history buffers. A wireless receiver may communicate with a wireless transmitter that an error is detected and that the history buffers of the wireless transmitter should be flushed or cleared.

Abstract: A method for treating cancer includes administering to a subject in need thereof an antibody against a transmembrane and coiled-coil domains protein 3 (TMCC3), wherein the antibody binds to an epitope in an extracellular domain of TMCC3. The antibody binds to an epitope in an intercoil domain of TMCC3. A method of diagnosing or assessing a cancer condition includes assessing a level of expression or activity of a transmembrane and coiled-coil domains protein 3 (TMCC3) in a sample, wherein an increase in the level of expression of activity of TMCC3 as compared to a standard indicates the presence of cancer stem cells in the sample.