Abstract: Disclosed is a set of compounds useful as glucan synthase inhibitors having the generic structure of Formula I: wherein the various moieties A, D, R6, etc., are as defined in the specification. These compounds are useful in treating or preventing fungal infections in a patient.

Abstract: In its many embodiments, the present invention provides -substituted pyridazinone compounds as glucan synthase inhibitors, methods of preparing such compounds, pharmaceutical including one or more of such compounds, methods of preparing pharmaceutical formulations including one or more such compounds or one or more such compounds along with other antifungal agents, and methods of treatment, prevention, inhibition, or amelioration of one or more fungal infections associated with glucan synthase using such compounds or pharmaceutical compositions.

Abstract: Drain products/systems and methods for installation are provided for diverting water away from a structure, e.g., a home's foundation. The drain products/systems are designed for use with conventional gutter and downspout systems and are adapted for installation/use at ground level. The disclosed drain products/systems are defined by a base and a side wall that surrounds the base on three sides thereof. The side wall which surrounds the base is typically defined by an inner wall portion, a bridging portion and an outer wall portion. The outer wall portion is advantageously of greater height than the inner wall portion. The difference in height between the outer wall portion and the inner wall portion typically defines a downwardly extending U-shaped portion. The disclosed drain products/systems offer superior flexibility to homeowners and/or contractors/builders, permitting efficient and reliable installation and use in countless terrains and environmental circumstances.