Patents by Inventor Johnathan A. Napier

Johnathan A. Napier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11913007
    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: February 27, 2024
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Jörg Bauer, Johnathan A. Napier, Olga Sayanova
  • Publication number: 20220170036
    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
    Type: Application
    Filed: December 16, 2021
    Publication date: June 2, 2022
    Inventors: Jörg Bauer, Johnathan A. Napier, Olga Sayanova
  • Publication number: 20210290577
    Abstract: A recombinant camelina plant or cell comprising one or more polynucleotides encoding a A6-desaturase, a A6-elongase and a A5-desaturase operably linked with one or more regulatory sequences.
    Type: Application
    Filed: December 31, 2020
    Publication date: September 23, 2021
    Inventors: Johnathan Napier, Olga Sayanova, Noemi Ruiz Lopez, Richard Haslam
  • Patent number: 10881631
    Abstract: A recombinant camelina plant or cell comprising one or more polynucleotides encoding a ?6-desaturase, a ?6-elongase and a ?5-desaturase operably linked with one or more regulatory sequences.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: January 5, 2021
    Assignee: ROTHAMSTED RESEARCH LTD.
    Inventors: Johnathan Napier, Olga Sayanova, Noemi Ruiz-Lopez, Richard Haslam
  • Publication number: 20190323022
    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
    Type: Application
    Filed: July 3, 2019
    Publication date: October 24, 2019
    Inventors: Jörg BAUER, Johnathan A. Napier, Olga Sayanova
  • Patent number: 10351870
    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: July 16, 2019
    Assignee: BASF Plant Science Company GmbH
    Inventors: Jörg Bauer, Johnathan A. Napier, Olga Sayanova
  • Patent number: 10208270
    Abstract: The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: February 19, 2019
    Assignee: BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Laurent Marty, Sten Stymne, Jenny Lindberg Yilmaz, Johnathan A. Napier, Olga Sayanova, Richard Haslam, Ruiz Lopez Noemi
  • Publication number: 20180312888
    Abstract: The invention relates to genetically modified organisms with enhanced production of omega-3 long chain polyunsaturated fatty acids.
    Type: Application
    Filed: June 11, 2018
    Publication date: November 1, 2018
    Inventors: Johnathan A. Napier, Olga Sayanova, Mary Hamilton, Royah Vaezi
  • Publication number: 20170067070
    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
    Type: Application
    Filed: November 15, 2016
    Publication date: March 9, 2017
    Inventors: Jörg Bauer, Johnathan A. Napier, Olga Sayanova
  • Patent number: 9493520
    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: November 15, 2016
    Assignee: BASF Plant Science Company GmbH
    Inventors: Jörg Bauer, Johnathan A. Napier, Olga Sayanova
  • Publication number: 20160272951
    Abstract: The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
    Type: Application
    Filed: May 20, 2016
    Publication date: September 22, 2016
    Inventors: Toralf Senger, Laurent MARTY, Sten STYMNE, Jenny LINDBERG YILMAZ, Johnathan A. NAPIER, Olga SAYANOVA, Richard HASLAM, Ruiz Lopez NOEMI
  • Patent number: 9388437
    Abstract: The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucletides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: July 12, 2016
    Assignee: BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Laurent Marty, Sten Stymne, Jenny Lindberg Yilmaz, Johnathan A. Napier, Olga Sayanova, Richard Haslam, Ruiz Lopez Noemi
  • Publication number: 20150275243
    Abstract: The invention relates to genetically modified organisms with enhanced production of omega-3 long chain polyunsaturated fatty acids.
    Type: Application
    Filed: October 1, 2013
    Publication date: October 1, 2015
    Applicant: ROTHAMSTED RESEARCH LIMITED
    Inventors: Johnathan A. Napier, Olga Sayanova, Mary Hamilton, Royah Vaezi
  • Patent number: 9139854
    Abstract: The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerin and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: September 22, 2015
    Assignee: BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Jörg Bauer, Johnathan A. Napier
  • Publication number: 20150216828
    Abstract: A recombinant camelina plant or cell comprising one or more polynucleotides encoding a ?6-desaturase, a ?6-elongase and a ?5-desaturase operably linked with one or more regulatory sequences.
    Type: Application
    Filed: April 12, 2013
    Publication date: August 6, 2015
    Applicant: Rothamsted Research Ltd.
    Inventors: Johnathan Napier, Olga Sayanova, Noemi Ruiz-Lopez, Richard Haslam
  • Patent number: 8993841
    Abstract: The invention provides isolated nucleic acid molecules which encodes a novel fatty acid nECR. The invention also provides recombinant expression vectors containing nECR nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: March 31, 2015
    Assignee: BASF Plant Science Company GmbH
    Inventors: Johnathan A. Napier, Olga Sayanova, Frederic Beaudoin
  • Publication number: 20140335579
    Abstract: The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerin and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.
    Type: Application
    Filed: July 23, 2014
    Publication date: November 13, 2014
    Inventors: Toralf Senger, Jörg Bauer, Johnathan A. Napier
  • Patent number: 8822662
    Abstract: The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerina and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: September 2, 2014
    Assignee: BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Jörg Bauer, Johnathan A. Napier
  • Patent number: 8785727
    Abstract: The present invention relates to a polynucleotide from Emiliana huxleyi which codes for a desaturase and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotide according to the invention, and to the polypeptides encoded by the polynucleotide. The invention furthermore relates to antibodies against the polypeptide according to the invention. Finally, the invention also relates to production methods for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: July 22, 2014
    Assignee: Rothamsted Research Ltd.
    Inventors: Joerg Bauer, Johnathan A. Napier, Olga Sayanova
  • Publication number: 20130097733
    Abstract: The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucletides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
    Type: Application
    Filed: June 21, 2011
    Publication date: April 18, 2013
    Applicant: BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Laurent Marty, Sten Stymne, Jenny Lindberg Yilmaz, Johnathan A. Napier, Olga Sayanova, Richard Haslam, Ruiz Lopez Noemi