Patents by Inventor Johnathan C. Maher

Johnathan C. Maher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mannose derivatives for killing tumor cells
    Patent number: 8242167
    Abstract: A method for treating cancer by killing selected tumor cells such as human breast, non-small cell lung cancer cells, pancreatic cancer cells, osteosarcoma cancer cells, and glioblastoma cells, includes administering to a patient in need of treatment, an effective amount of at least one mannose analog such as 2-DG or 2-FM or 2-CM. The killing is believed to be due to an interference with glycosylation. A theranostic method includes determining whether a patient. cancer tumor sample comprises cells sensitive to killing to at least one mannose analog due to an interference with glycosylation.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: August 14, 2012
    Assignee: University of Miami
    Inventors: Theodore J. Lampidis, Metin Kurtoglu, Johnathan C. Maher