Patents by Inventor Johnathan Seidman

Johnathan Seidman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • &ggr;, &dgr; T cell receptor and methods for detection
    Patent number: 6313263
    Abstract: The present invention provides purified polypeptides which comprise at least a portion of a &dgr; T cell receptor polypeptide, a &ggr; T cell receptor polypeptide, a &ggr;, &dgr; T cell receptor complex or a &ggr;, &ggr; T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.
    Type: Grant
    Filed: February 10, 1997
    Date of Patent: November 6, 2001
    Assignees: Astra AB, President and Fellows of Harvard College, Dana-Farber Cancer Institute
    Inventors: Michael B. Brenner, Jack L. Strominger, Johnathan Seidman, Stephen H. Ip, Michael S. Krangel
  • .gamma., .delta. T cell receptor and methods for detection
    Patent number: 5601822
    Abstract: The present invention provides purified polypeptides which comprise at least a portion of a .delta. T cell receptor polypeptide, a .gamma. T cell receptor polypeptide, a .gamma., .delta. T cell receptor complex or a .gamma., .gamma. T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided.Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.
    Type: Grant
    Filed: November 19, 1993
    Date of Patent: February 11, 1997
    Assignees: T Cell Sciences, Inc., President and Fellows of Harvard College, Dana Farber Cancer Institute
    Inventors: Michael B. Brenner, Jack L. Strominger, Johnathan Seidman, Stephen H. Ip, Michael S. Krangel
  • .GAMMA., .delta.T cell receptor and methods and detection
    Patent number: 5340921
    Abstract: The present invention provides purified polypeptides which comprise at least a portion of a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide, a .gamma., .delta.T cell receptor complex or a .gamma., .gamma.T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided.Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.
    Type: Grant
    Filed: February 19, 1987
    Date of Patent: August 23, 1994
    Assignees: T Cell Sciences, Inc., The Dana-Farber Cancer Institute, President & Fellows of Harvard College
    Inventors: Michael B. Brenner, Jack L. Strominger, Johnathan Seidman, Stephen H. Ip, Michael S. Krangel