Patents by Inventor Johnathan Tilly

Johnathan Tilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protection of female reproductive system from natural and artifical insults
    Publication number: 20070157331
    Abstract: Described are methods for protecting the female reproductive system against natural and artificial insults by administering to women a composition comprising an agent that antagonizes one or more acid sphingomyelinase (ASMase) gene products. Specifically, methods disclosed herein serve to protect women's germline from damage resulting from cancer therapy regimens including chemotherapy or radiotherapy. In one aspect, the method preserves, enhances, or revives ovarian function in women, by administering to women a composition containing sphingosine-1-phosphate, or an analog thereof. Also disclosed are methods to prevent or ameliorate menopausal syndromes and to improve in vitro fertilization techniques.
    Type: Application
    Filed: March 7, 2007
    Publication date: July 5, 2007
    Applicant: Massachusetts General Hospital, Partners HealthCare Research Ventures & Licensing
    Inventors: Johnathan Tilly, Richard Kolesnick