Patents by Inventor Johnny CASTILLO MELEAN

Johnny CASTILLO MELEAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047327
    Abstract: The present application relates to a diagnostic composition comprising: a. a compound of Formula I, b. ethanol, c. water, and d. a hydroxycarboxylic acid, a salt of a hydroxycarboxylic acid or a mixture thereof. The diagnostic composition can be used in the selective detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease (AD) and other tauopathies, for example, using Positron Emission Tomography (PET). The present invention also relates to a method of preparing the claimed diagnostic composition.
    Type: Application
    Filed: January 22, 2019
    Publication date: February 18, 2021
    Inventors: Johnny CASTILLO MELEAN, Thomas BETZEL, Mathias BERNDT, Hanno SCHIEFERSTEIN, Heiko KROTH, Jérôme MOLETTE, Vincent DARMENCY, Emanuele GABELLIERI
  • Publication number: 20210038747
    Abstract: The present invention relates to a novel method of preparing a compound of the formula I. Diagnostic compositions and their use in the selective detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease (AD) and other tauopathies, for example, using Positron Emission Tomography (PET) imaging are also disclosed.
    Type: Application
    Filed: January 22, 2019
    Publication date: February 11, 2021
    Inventors: Marion ZERNA, Mathias BERNDT, Hanno SCHIEFERSTEIN, Johnny CASTILLO MELEAN, Heiko KROTH, Jérôme MOLETTE, Vincent DARMENCY, Emanuele GABELLIERI