Patents by Inventor Johnny Eugene CROY

Johnny Eugene CROY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-alpha-synuclein antibodies and uses thereof
    Patent number: 12459993
    Abstract: The present invention relates to anti-alpha-synuclein antibodies, and uses thereof for treating diseases such as Parkinson's disease.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: November 4, 2025
    Assignee: Eli Lilly and Company
    Inventors: Johnny Eugene Croy, Mansuo Lu Hayashi, Jirong Lu, Bo Ma, Ying Tang
  • MULTISPECIFIC BINDING MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20250304709
    Abstract: Multispecific binding molecules having a first binding domain targeting a blood brain barrier target and a second binding domain targeting a neuron target, astrocyte target and/or glial cell target, and uses thereof in aiding the treatment of central nervous system diseases including neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Parkinson's diseases, Progressive Supranuclear Palsy (PSP), Amyotrophic Lateral Sclerosis (ALS), Frontal Temporal Dementia (FTD), autism, catalepsy, encephalitis, migraine, and Tourette's.
    Type: Application
    Filed: April 28, 2023
    Publication date: October 2, 2025
    Inventors: Riazul ALAM, Johnny Eugene CROY, Hiroaki TANI
  • SARM1 RNAi AGENTS
    Publication number: 20250249118
    Abstract: Provided herein are SARM1 RNAi agents and compositions comprising a SARM1 RNAi agent. Also provided herein are methods of using the SARM1 RNAi agents or compositions comprising a SARM1 RNAi agent in reducing SARM1 expression and/or treating SARM1-mediated neurological diseases.
    Type: Application
    Filed: January 31, 2025
    Publication date: August 7, 2025
    Inventors: Riazul ALAM, Nicholas A. BABB, Johnny Eugene CROY, Gregory Lawrence LACKNER, Yea Jin KAESER-WOO
  • TRANSFERRIN RECEPTOR BINDING PROTEINS AND CONJUGATES
    Publication number: 20240059784
    Abstract: Provided herein are proteins comprising one monovalent human TfR binding domain (“human TfR binding proteins”), proteins comprising one monovalent mouse TfR binding domain (“mouse TfR binding proteins”), conjugates comprising such human or mouse TfR binding proteins, e.g., human TfR binding proteins-dsRNA conjugates, pharmaceutical compositions comprising human TfR binding proteins or conjugates, and methods of treating CNS diseases (e.g., neurodegenerative disease such as neurodegenerative synucleinopathy or tauopathy) using human TfR binding proteins or conjugates.
    Type: Application
    Filed: August 7, 2023
    Publication date: February 22, 2024
    Inventors: Riazul Alam, Alberto Alvarado, Forest Hoyt Andrews, Nicholas Alan Babb, Deepa Balasubramaniam, Guillermo S. Cortez, Johnny Eugene Croy, David Albert Driver, Ross Edward Fellows, Daniel Girard, Lacie Chauvigne-Hines, Feng Liu, Hiroaki Tani, Isabel C. Gonzalez Valcarcel, Scott Alan Lawrence, Nalini Hosahalli Kulkarni, Jeremy S York
  • Anti-Alpha-Synuclein Antibodies and Uses Thereof
    Publication number: 20220048982
    Abstract: The present invention relates to anti-alpha-synuclein antibodies, and uses thereof for treating diseases such as Parkinson's disease.
    Type: Application
    Filed: December 9, 2019
    Publication date: February 17, 2022
    Applicant: Eli Lilly and Company
    Inventors: Johnny Eugene CROY, Mansuo Lu HAYASHI, Jirong LU, Bo MA, Ying TANG