Patents by Inventor Johnny Kung

Johnny Kung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CCCTC-binding factor (CTCF) RNA interactome
    Patent number: 11001841
    Abstract: This invention relates to methods and compositions for selectively reactivating or downregulating certain genes, e.g., genes regulated by zinc-finger protein CCCTC-binding factor (CTCF) on autosomes (e.g., imprinted genes, tumor suppressors, cancer) and the inactive X chromosome (Xi), e.g., genes associated with X-linked diseases, e.g., Rett Syndrome, Factor VIII or IX deficiency, Fragile X Syndrome, Duchenne muscular dystrophy, and PNH, in heterozygous females carrying a mutated allele, in addition to a functional wildtype or hypomorphic allele.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: May 11, 2021
    Assignee: The General Hospital Corporation
    Inventors: Jeannie T. Lee, Johnny Kung, Barry Kesner
  • CCCTC-Binding Factor (CTCF) RNA Interactome
    Publication number: 20190309291
    Abstract: This invention relates to methods and compositions for selectively reactivating or downregulating certain genes, e.g., genes regulated by zinc-finger protein CCCTC-binding factor (CTCF) on autosomes (e.g., imprinted genes, tumor suppressors, cancer) and the inactive X chromosome (Xi), e.g., genes associated with X-linked diseases, e.g., Rett Syndrome, Factor VIII or IX deficiency, Fragile X Syndrome, Duchenne muscular dystrophy, and PNH, in heterozygous females carrying a mutated allele, in addition to a functional wildtype or hypomorphic allele.
    Type: Application
    Filed: April 13, 2018
    Publication date: October 10, 2019
    Inventors: Jeannie T. Lee, Johnny Kung, Barry Kesner
  • CCCTC-Binding Factor (CTCF) RNA Interactome
    Publication number: 20150376612
    Abstract: This invention relates to methods and compositions for selectively reactivating or downregulating certain genes, e.g., genes regulated by zinc-finger protein CCCTC-binding factor (CTCF) on autosomes (e.g., imprinted genes, tumor suppressors, cancer) and the inactive X chromosome (Xi), e.g., genes associated with X-linked diseases, e.g., Rett Syndrome, Factor VIII or IX deficiency, Fragile X Syndrome, Duchenne muscular dystrophy, and PNH, in heterozygous females carrying a mutated allele, in addition to a functional wildtype or hypomorphic allele.
    Type: Application
    Filed: June 10, 2015
    Publication date: December 31, 2015
    Inventors: Jeannie T. Lee, Johnny Kung, Barry Kesner