Abstract: Provided herein are methods of determining that a subject has or is at risk of having a disease (e.g., cancer) using analysis of gene expression of loci identified in nucleic acid molecules derived from a cell-free biological sample of the subject.

Abstract: Provided herein are methods and systems for nucleic acid processing or analysis comprising generating a mixture comprising a first plurality of nucleic acid molecules derived from a biological sample of a subject, and a second plurality of nucleic acid molecules comprising sequences having at least one predetermined size; subjecting said first plurality of nucleic acid molecules, or derivative thereof; and second plurality of nucleic acid molecules or derivative thereof, to sequencing to generate a plurality of sequence reads; and processing said plurality of sequence reads to identify (i) a first set of sequence reads corresponding to at least a subset of said first plurality of nucleic acid molecules, and (ii) a second set of sequence reads corresponding to at least a subset of said second plurality of nucleic acid molecules, which second set of sequence reads corresponds to said sequences having said at least one predetermined size; and using said second set of sequence reads to identify one or more nuclei

Abstract: Provided herein are methods of cell-free nucleic acid size analysis. For example, methods herein can comprise preparing a first single stranded DNA library from a plurality of cell-free nucleic acid molecules from a subject and preparing a second single stranded DNA library from a plurality of cell-free nucleic acid molecules from a control.

Abstract: Provided herein are methods of determining that a subject has or is at risk of having a disease (e.g., cancer) using analysis of fragment enrichment or depletion on nucleic acid molecules derived from a cell-free biological sample of the subject.

Abstract: Provided herein are methods of determining that a subject has or is at risk of having a disease (e.g., cancer) using nucleic acid molecules derived from a cell-free biological sample of the subject.

Abstract: The invention is a method of determining a likelihood that a cancer patient will respond to immunotherapy based on a mutation metric obtained by sequencing a small panel of nucleic acid targets in patient's cell-free DNA.

Abstract: An LED device with high color-rendering index includes a substrate; three white light units arranged on the substrate, each of the white light units being an LED element that combines a blue light chip with fluorescent glue to produce a mixed light; and a red light unit arranged on the substrate among the three white light units and being an LED element that combines a red light chip with fluorescent powder to produced a mixed light. With the specific arrangement of positioning the red light unit among three white light units, a mixed light produced by the LED device is a visually comfortable warm white light with high color-rendering index. Therefore, the LED device can be used in an environment where a large quantity of LEDs are needed, so largely reduces the users' eye discomfort.

Abstract: An LED device with high color-rendering index includes a substrate; three white light units arranged on the substrate, each of the white light units being an LED element that combines a blue light chip with fluorescent glue to produce a mixed light; and a red light unit arranged on the substrate among the three white light units and being an LED element that combines a red light chip with fluorescent powder to produced a mixed light. With the specific arrangement of positioning the red light unit among three white light units, a mixed light produced by the LED device is a visually comfortable warm white light with high color-rendering index. Therefore, the LED device can be used in an environment where a large quantity of LEDs are needed, so largely reduces the users' eye discomfort.

Abstract: A light-emitting diode (LED) with high color-rendering index includes a substrate being provided on one face with a plurality of recesses; a plurality of first chips being separately disposed in the recesses and adapted to emit blue light; a plurality of fluorescent glues being separately filled in the recesses; at least one second chip being disposed on the substrate at a predetermined position to electrically connect to the first chips, and adapted to emit red light; and a light-transmittable layer provided on the substrate to protectively cover the first chips, the fluorescent glues, and the second chip. The blue light emitted from the first chips and the yellow or green light from the fluorescent glues are mixed first, and the produced light is then further mixed with the red light emitted from the second chip to produce warm white light, which is then projected through the light-transmittable layer.

Abstract: In one embodiment, a method for upfront specification of lot process parameters to enable automated processing is disclosed. The method comprises specifying a combination of one or more process parameters in a template associated with a tool, the process parameters associated with a process flow for a lot to be processed by the tool, and subsequent to the specifying, automatically retrieving by the tool the specified combination of process parameters at least one of when the lot arrives at the tool for processing, during processing of the lot by the tool, and after processing of the lot by the tool, wherein automatically retrieving includes retrieving the specified combination without human intervention. Other embodiments are also described.

Abstract: According to one aspect of the invention, a method for managing the storage of semiconductor material is provided. The method may include processing a plurality of semiconductor substrates with a first type of semiconductor substrate processing tool to create a plurality of a first type of semiconductor substrate, determining the contents of a plurality of storage devices, each storage device being connected to a second type of semiconductor substrate processing tool, and selecting a maximum number of the first type of semiconductor substrate to be stored in each storage device, the maximum number being less than a storage capacity of the respective storage device.

Abstract: A system, method, and/or program that enables a material handling system to proactively stage lots at ideally located stockers. Input containing the lots to be processed on a process machine is entered into a manual order queue (“MOQ”). The system, method, and/or program then proactively determines the location for the staging of the lots to be processed based at least in part on the state of the stockers.