Patents by Inventor Johnny Y. Nagasawa

Johnny Y. Nagasawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20130231333
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: September 15, 2011
    Publication date: September 5, 2013
    Applicant: ARAGON PHARMACEUTICALS, INC.
    Inventors: Nicholas D. Smith, Mehmet Kahraman, Steven P. Govek, Johnny Y. Nagasawa, Andiliy G. Lai, Jackaline D. Julien, Mark R. Herbert, Celine Bonnefous, Karensa L. Douglas
  • Estrogen receptor modulators and uses thereof
    Patent number: 8455534
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: June 4, 2013
    Assignee: Aragon Pharmaceuticals, Inc.
    Inventors: Nicholas D. Smith, Mehmet Kahraman, Steven P. Govek, Johnny Y. Nagasawa, Andiliy G. Lai, Jackaline D. Julien, Celine Bonnefous
  • ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20130116232
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: June 8, 2011
    Publication date: May 9, 2013
    Applicant: ARAGON PHARMACEUTICALS, INC.
    Inventors: Mehmet Kahraman, Steven P. Govek, Johnny Y. Nagasawa, Nicholas D. Smith
  • ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20130012561
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Applicant: ARAGON PHARMACEUTICALS, INC.
    Inventors: Nicholas D. SMITH, Mehmet Kahraman, Steven P. Govek, Johnny Y. Nagasawa, Andiliy G. Lai, Jackaline D. Julien, Celine Bonnefous
  • Estrogen receptor modulators and uses thereof
    Patent number: 8299112
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: October 30, 2012
    Assignee: Aragon Pharmaceuticals, Inc.
    Inventors: Nicholas D. Smith, Mehmet Kahraman, Steven P. Govek, Johnny Y. Nagasawa, Andiliy G. Lai, Jackaline D. Julien, Celine Bonnefous
  • PROTEIN KINASE MODULATORS
    Publication number: 20120208792
    Abstract: The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate Pim kinase activity and/or FMS-like tyrosine kinase (Flt) activity. The invention also relates in part to methods for using such molecules.
    Type: Application
    Filed: December 8, 2011
    Publication date: August 16, 2012
    Applicant: CYLENE PHARMACEUTICALS, INC.
    Inventors: Peter C. Chua, Mustapha Haddach, Johnny Y. Nagasawa, Fabrice Pierre, Jeffrey P. Whitten
  • Protein kinase modulators
    Patent number: 8168651
    Abstract: The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate Pim kinase activity and/or FMS-like tyrosine kinase (Flt) activity. The invention also relates in part to methods for using such molecules.
    Type: Grant
    Filed: March 2, 2009
    Date of Patent: May 1, 2012
    Assignee: Cylene Pharmaceuticals, Inc.
    Inventors: Peter C. Chua, Mustapha Haddach, Johnny Y. Nagasawa, Fabrice Pierre, Jeffrey P. Whitten
  • ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20120071535
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: September 15, 2011
    Publication date: March 22, 2012
    Applicant: Aragon Pharmaceuticals, Inc.
    Inventors: Nicholas D. SMITH, Mehmet KAHRAMAN, Steven P. GOVEK, Johnny Y. NAGASAWA, Andiliy G. LAI, Jackaline D. Julien, Celine Bonnefous
  • NOVEL COMPOSITIONS AND METHODS OF USE
    Publication number: 20110269741
    Abstract: Described herein are novel enzyme inhibitors. In some embodiments the enzyme inhibitors are integrase inhibitors, particularly HIV integrase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV integrase as a method of treating or preventing HIV, AIDS or related disorders.
    Type: Application
    Filed: March 28, 2011
    Publication date: November 3, 2011
    Applicant: Ardea Biosciences, Inc.
    Inventors: Huanming CHEN, Jianlin SONG, Jean-Michel VERNIER, Anthony B. PINKERTON, Johnny Y. NAGASAWA
  • NOVEL COMPOSITIONS AND METHODS OF USE
    Publication number: 20110166123
    Abstract: Described herein are novel enzyme inhibitors. In some embodiments the enzyme inhibitors are integrase inhibitors, particularly HIV integrase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV integrase as a method of treating or preventing HIV, AIDS or related disorders.
    Type: Application
    Filed: January 7, 2009
    Publication date: July 7, 2011
    Applicant: AARDEA BIOSCIENCES, INC.
    Inventors: Huanming Chen, Jianlin Song, Jean-Michel Vernier, Anthony B. Pinkerton, Johnny Y. Nagasawa
  • Methods of preparing quinolone analogs
    Patent number: 7834180
    Abstract: Compounds having formula 1: are produced by contacting a compound having formula (6A) with a compound having formula (7), or tautomers thereof, in the presence of a non-nucleophilic base, wherein V, A, Z, L, L1, W, X, B?, R and n are as defined herein.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: November 16, 2010
    Assignee: Cylene Pharmaceuticals, Inc.
    Inventors: Peter C. Chua, Johnny Y. Nagasawa, Michael Schwaebe, Fabrice Pierre
  • Quinolone analogs
    Patent number: 7816406
    Abstract: The present invention provides quinolone analogs which may inhibit cell proliferation and/or induce cell apoptosis. The present invention also provides methods of preparing quinolone analogs, and methods of using the same.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: October 19, 2010
    Assignee: Cylene Pharmaceuticals, Inc.
    Inventors: Jeffrey P. Whitten, Fabrice Pierre, Collin Regan, Michael Schwaebe, Johnny Y. Nagasawa, Peter Chua
  • Methods of preparing quinolone analogs
    Patent number: 7816524
    Abstract: Compounds having formula 1 are produced by contacting a compound having formula(6A) with a compound having formula (7), or tautomers thereof, in the presence of a non-nucleophilic base, wherein V, A, Z, L, L1,W, X, B?, R and N are as defined herein.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: October 19, 2010
    Assignee: Cylene Pharmaceuticals, Inc.
    Inventors: Peter C. Chua, Johnny Y. Nagasawa, Michael Schwaebe, Fabrice Pierre
  • PROTEIN KINASE MODULATORS
    Publication number: 20090239859
    Abstract: The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate Pim kinase activity and/or FMS-like tyrosine kinase (Flt) activity. The invention also relates in part to methods for using such molecules.
    Type: Application
    Filed: March 2, 2009
    Publication date: September 24, 2009
    Inventors: Peter C. CHUA, Mustapha Haddach, Johnny Y. Nagasawa, Fabrice Pierre, Jeffrey P. Whitten
  • METHODS OF PREPARING QUINOLONE ANALOGS
    Publication number: 20090082565
    Abstract: The present invention relates to the preparation of compounds which are capable of inducing cell death such as apoptotic cell death (apoptosis), and/or for reducing a cell proliferative disorder.
    Type: Application
    Filed: November 19, 2008
    Publication date: March 26, 2009
    Applicant: Cylene Pharmaceuticals, Inc.
    Inventors: Peter C. CHUA, Johnny Y. Nagasawa, Michael Schwaebe, Fabrice Pierre