Abstract: A multi-position micro-fluidic valve system that includes an actuator assembly with a housing and a drive shaft rotatably disposed in the housing for rotational displacement about a drive axis thereof. One end of the drive shaft is configured to couple to a drive motor for selective rotation of the drive shaft about the drive axis. One of at least two different multi-position fluid valve devices can be removably mated to the actuator assembly. Each valve device is configured for rotational movement of a corresponding valve shaft about a valve rotational axis thereof between a plurality of discrete fluid distribution positions. A coupling device selectively and removably mounts the valve shaft of the respective valve device to the drive shaft of the actuator assembly. This enables selective positioning of the multi-position fluid valve device at a discrete one of the plurality for discrete distribution positions.

Abstract: While a large primary stream (24) of analytes flow from a chromatographic column (20) to containers of a receiver (108), small samples of the analytes are diverted for flow to a mass spectrometer (54) for analysis, by use of a transfer module (102). The transfer module includes a stator (110) and a rotor or shuttle (114). The shuttle has an aliquot passage (120) that initially lies in a first position where the primary stream flows through it so the aliquot passage receives a small sample. The shuttle then moves to a second position where the aliquot passage (at 122) is aligned with a pump (134) that pumps fluid out of the aliquot passage to the mass spectrometer.

Abstract: While a large primary stream (24) of analytes flow from a chromatographic column (20) to containers of a receiver (108), small samples of the analytes are diverted for flow to a mass spectrometer (54) for analysis, by use of a transfer module (102). The transfer module includes a stator (110) and a rotor or shuttle (114). The shuttle has an aliquot passage (120) that initially lies in a first position where the primary stream flows through it so the aliquot passage receives a small sample. The shuttle then moves to a second position where the aliquot passage (at 122) is aligned with a pump (134) that pumps fluid out of the aliquot passage to the mass spectrometer.

Abstract: A multi-function, random access, dual, three-way valve for use with fluid switching and the like is provided, whereby a first fluid flow to the valve is selectively placed in fluid communication with a first or a second outlet passage from the valve for selectively transferring the first fluid flow and a second fluid flow to the valve is, independent of the flow path of the first fluid, selectively placed in fluid communication with a third or a fourth outlet from the valve for simultaneously transferring the second fluid flow. A rotor element rotatably movable relative to a stationary stator element to at least four discrete angular positions actuates to multi-function switching capabilities of the valve when the rotor element is selectively placed in one of the at least four discrete positions. The valve directs the first fluid flow to one of two alternate outlet passages and, simultaneously and independently, directs the second fluid flow to one of at least two different outlet passages.

Abstract: A multi-function, random access, dual, three-way valve for use with fluid switching and the like is provided, whereby a first fluid flow to the valve is selectively placed in fluid communication with a first or a second outlet passage from the valve for selectively transferring the first fluid flow and a second fluid flow to the valve is, independent of the flow path of the first fluid, selectively placed in fluid communication with a third or a fourth outlet from the valve for simultaneously transferring the second fluid flow. A rotor element rotatably movable relative to a stationary stator element to at least four discrete angular positions actuates to multi-function switching capabilities of the valve when the rotor element is selectively placed in one of the at least four discrete positions. The valve directs the first fluid flow to one of two alternate outlet passages and, simultaneously and independently, directs the second fluid flow to one of at least two different outlet passages.

Abstract: A rotary fluid switching valve has facewise adjacent rotor and stator faces of materials that result in an exceptionally long lifetime. One face is of a fluorocarbon-containing polymer, while the other face is Tungsten Carbide/Carbon (WC/C). The WC/C coating is preferably on a metal stator which has machined ports to accept tubing fittings that connect to stator passages that extend to the interface of stator and rotor.

Abstract: A wash system for a fluid handling system that permits simultaneous washing of a plurality of parallel fluid channels is disclosed. In one aspect of the invention, a specialized rotary wash valve is described. In another aspect of the invention a system which incorporates wash and selector valves is described which permits a plurality of separate fluid lines emerging from the selector valve to be washed simultaneously.

Abstract: A wash system for a fluid handling system that permits simultaneous washing of a plurality of parallel fluid channels is disclosed. In one aspect of the invention, a specialized rotary wash valve is described. In another aspect of the invention a system which incorporates wash and selector valves is described which permits a plurality of separate fluid lines emerging from the selector valve to be washed simultaneously.

Abstract: A multi-function valve apparatus for use with a Probe-In-Loop (PIL) architecture sample injection assembly which enables both Partial-Fill and Complete-Fill injections. The rotor element is rotatable about a rotation axis relative the stator between: a Load Position, an Overfill Position, and an Injection Position. In the Load Position, a first bridge channel fluidly couples a metering syringe to the sample loop assembly enabling the probe to aspirate one of a discrete volume of sample into the probe, during a Partial-Fill Mode, and a second volume of sample into the probe, during a Complete-Fill Mode. In the Overfill Position, in the Complete-Fill Mode, a second bridge channel fluidly couples a downstream loop portion to a waste port, and the first bridge channel fluidly couples the metering syringe to an upstream loop portion of the sample loop assembly.

Abstract: While a large primary stream (24) of analytes flow from a chromatographic column (20) to containers of a receiver (108), small samples of the analytes are diverted for flow to a mass spectrometer (54) for analysis, by use of a transfer module (102). The transfer module includes a stator (110) and a rotor or shuttle (114). The shuttle has an aliquot passage (120) that initially lies in a first position where the primary stream flows through it so the aliquot passage receives a small sample. The shuttle then moves to a second position where the aliquot passage (at 122) is aligned with a pump (134) that pumps fluid out of the aliquot passage to the mass spectrometer.

Abstract: A rotary fluid switching valve has facewise adjacent rotor and stator faces of materials that result in an exceptionally long lifetime. One face is of a fluorocarbon-containing polymer, while the other face is Tungsten Carbide/Carbon (WC/C). The WC/C coating is preferably on a metal stator which has machined ports to accept tubing fittings that connect to stator passages that extend to the interface of stator and rotor.

Abstract: A valve that receives sample and solvent streams, and delivers slugs of different fluid samples separated by slugs of the solvent, to a detector. The valve includes a stator (140) having a central hole (40) and a circle of sample holes (51-54) and solvent holes (91-94). The valve also includes a rotor (150) with a first groove (162) that connects one of the sample or solvent holes to the central hole to flow to the detector. The first groove is wide enough and the space between adjacent supply holes is small enough, that as the first groove moves from one hole of the circle to the next, the groove becomes partially open to the next hole before it leaves the last hole to minimize the sudden increase in pressure along the flow to the detector.