Patents by Inventor Jon Dobson

Jon Dobson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cell targeting and activation using magnetic particles
    Patent number: 8469034
    Abstract: The present invention provides a method of selectively activating and/or targeting stem cells which enables the cells to then be manipulated mechanically in a remote manner wherein the method comprises magnetically manipulating a stem cell in vivo or in vitro by the association of a magnetisable particle within the stem cell.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: June 25, 2013
    Assignee: MICA Biosystems Limited
    Inventors: Jon Dobson, Alicia El Haj
  • GENE DELIVERY
    Publication number: 20120288505
    Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell, the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.
    Type: Application
    Filed: June 27, 2012
    Publication date: November 15, 2012
    Inventors: Jon DOBSON, Christopher D. BATICH
  • Gene delivery
    Patent number: 8232102
    Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: July 31, 2012
    Assignee: Nanotherics Ltd.
    Inventors: Jon Dobson, Christopher D. Batich
  • STEM CELL TARGETING AND ACTIVATION USING MAGNETIC PARTICLES
    Publication number: 20110034753
    Abstract: The present invention provides a method of selectively activating and/or targeting stem cells which enables the cells to then be manipulated mechanically in a remote manner wherein the method comprises magnetically manipulating a stem cell in vivo or in vitro by the association of a magnetisable particle within the stem cell.
    Type: Application
    Filed: December 8, 2004
    Publication date: February 10, 2011
    Inventors: Jon Dobson, Alicia El Haj
  • MAGNETIC DELIVERY DEVICE
    Publication number: 20100298816
    Abstract: A method of delivering a reagent into a cell comprising positioning at least one cell, and at least one magnetically susceptible particle attached to the reagent, in the magnetic field of a Halbach array such that the magnetically susceptible particle is attracted to and contacts the cell is described together with an apparatus for delivery of the reagent.
    Type: Application
    Filed: September 10, 2008
    Publication date: November 25, 2010
    Applicant: KEELE UNIVERSITY
    Inventor: Jon Dobson
  • Targeted Therapy
    Publication number: 20090123366
    Abstract: In order to target a diseased material in a subject, a monocyte, or monocyte-derived cell, such as a macrophage, which incorporates a magnetic material, such as a magnetic particle or a ferrofluid, preferably having a biocompatible coating, is proposed to be administered. A magnetic energy source may then be applied to the subject to destroy, rupture or inactivate the diseased material. Alternatively, the monocyte or monocyte derived cell may additionally include a therapeutic agent, which is thereby targeted at the diseased material.
    Type: Application
    Filed: April 3, 2007
    Publication date: May 14, 2009
    Applicant: Keele University
    Inventors: Jon Dobson, Claire Lewis, Helen Byrne
  • Gene Delivery
    Publication number: 20080286361
    Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.
    Type: Application
    Filed: April 21, 2006
    Publication date: November 20, 2008
    Applicants: KEELE UNIVERSITY, UNIVERSITY OF FLORIDA RESEARCH FOUNDATION
    Inventors: Jon Dobson, Christopher D. Batich
  • Method of making nanoparticles
    Patent number: 7332351
    Abstract: Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: February 19, 2008
    Assignee: The University of Florida
    Inventors: Weihong Tan, Swadeshmukul Santra, Peng Zhang, Rovelyn Tapec, Jon Dobson
  • Method of making nanoparticles
    Publication number: 20060228554
    Abstract: Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications.
    Type: Application
    Filed: July 25, 2005
    Publication date: October 12, 2006
    Inventors: Weihong Tan, Swadeshmukul Santra, Peng Zhang, Rovelyn Tapec, Jon Dobson
  • Method for identifying cells
    Patent number: 6924116
    Abstract: Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: August 2, 2005
    Assignee: University of Florida
    Inventors: Weihong Tan, Swadeshmukul Santra, Peng Zhang, Rovelyn Tapec, Jon Dobson
  • Coated nanoparticles
    Patent number: 6548264
    Abstract: Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: April 15, 2003
    Assignee: University of Florida
    Inventors: Weihong Tan, Swadeshmukul Santra, Peng Zhang, Rovelyn Tapec, Jon Dobson
  • Method for identifying cells
    Publication number: 20020098529
    Abstract: Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications.
    Type: Application
    Filed: November 13, 2001
    Publication date: July 25, 2002
    Inventors: Weihong Tan, Swadeshmukul Santra, Peng Zhang, Rovelyn Tapec, Jon Dobson